Ramipril vs Lisinopril

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Written by BFH Staff Writer on December 13, 2022

Ramipril vs Lisinopril are effective blood pressure medications that ensure good renal and heart functions. Patients with problems managing their hypertension typically use these drugs to prevent further complications. Both act as angiotensin-converting-enzyme (ACE) inhibitors, a class of drugs that relaxes the veins and arteries to lower blood pressure.

But what exactly are the differences between Ramipril and Lisinopril? Continue reading to learn more about these two medications.

How different are Ramipril and Lisinopril?

There is not much of a difference between Ramipril and Lisinopril. The two medications have more similarities than one would think. They are both ACE inhibitors, giving patients almost the same benefits and side effects.

Among the two, Ramipril is linked with the lowest rate of all-cause mortality. Meanwhile, Lisinopril has been shown to be the least effective in lowering systolic and diastolic blood pressure.  Unlike Ramipril, Lisinopril is associated with the highest incidence of all-cause mortality.

What is Ramipril?

Ramipril is used to treat high blood pressure. It also lowers the danger and likelihood of death, heart attack, and stroke among patients. It can also be administered to individuals who have experienced a heart attack to treat heart failure as they recover.

Ramipril oral capsule is available both in a generic and a brand name. Altace is the brand name for Ramipril.

This medication may result in sudden swelling of your face, arms, legs, lips, tongue, throat, and intestines. If you get stomach pain or swelling in these regions while taking Ramipril, stop taking it immediately and call your doctor.

What is Lisinopril?

Like Ramipril, high blood pressure is also treated with Lisinopril. Lowering your blood pressure to an average level reduces the risk of heart attacks, kidney issues, and strokes. It helps patients survive longer after a heart attack and treats heart failure. Lisinopril works by relaxing blood vessels so blood can flow more easily.

Taking your first dose of Lisinopril at bedtime is best because it could make you feel lightheaded. You can take Lisinopril whenever you want after the first dose if you don’t experience any dizziness. Try to take it every day on the same schedule.

How do ACE inhibitor drugs work?

ACE inhibitors are prescription drugs for the heart that dilate or enlarge your blood arteries. It also results in decreased blood pressure. Additionally, these drugs increase the blood your heart pumps to lower your blood pressure. Thus, improving blood flow, which lessens the strain on your heart.

Some other uses of ACE inhibitors are the following:

  • Coronary artery disease
  • Heart failure
  • Diabetes
  • Certain chronic kidney diseases
  • Heart attacks
  • Scleroderma
  • Migraines

You can take ACE inhibitor drugs occasionally with another blood pressure drug, such as a diuretic or calcium channel blocker. You should note, however, that angiotensin receptor blockers and direct renin inhibitors should not be administered with ACE inhibitors.

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