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Glumetza is an extended-release formulation of metformin used to manage type 2 diabetes. It helps control blood sugar levels by improving insulin sensitivity and reducing glucose production in the liver.
Benefits:
- Provides long-lasting blood sugar control with once-daily dosing.
- Reduces insulin resistance and improves glucose metabolism.
- It may assist with weight management in diabetic patients.
- Lowers the risk of diabetes-related complications.
Dosage:
- Typically, it starts at 500 mg once daily with the evening meal.
- The maximum dose is 2000 mg daily, adjusted based on patient response.
Warnings and Precautions:
- It is not suitable for individuals with severe kidney disease or metabolic acidosis.
- It may increase the risk of lactic acidosis, particularly in patients with kidney or liver issues.
- Regular kidney function monitoring is required.
Usage Instructions:
- Take orally with food to minimize gastrointestinal discomfort.
- Do not crush, split, or chew extended-release tablets.
Storage Information:
- Store at room temperature, away from moisture and heat.
Common Side Effects:
- Mild: Nausea, diarrhea, bloating.
- Severe: Lactic acidosis, difficulty breathing (seek immediate medical attention).
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How is Glumetza different from regular metformin?
Glumetza is an extended-release version of metformin, designed to gradually release the medication throughout the day. This steadily affects blood sugar levels and reduces the risk of gastrointestinal side effects such as diarrhea and stomach cramps, which are familiar with immediate-release metformin. It also allows for once-daily dosing, improving convenience and adherence to treatment.
When should I take Glumetza?
Glumetza should be taken once daily with your evening meal. Taking it with food helps improve absorption and minimizes the risk of gastrointestinal discomfort. Taking it simultaneously each day is essential to maintain consistent blood sugar control. Swallow the tablet whole without crushing or chewing it, as breaking it may interfere with its extended-release properties.
Can Glumetza cause low blood sugar?
Glumetza alone does not typically cause low blood sugar (hypoglycemia) because it does not increase insulin production. However, when combined with insulin or other diabetes medications such as sulfonylureas, the risk of hypoglycemia increases. Symptoms of low blood sugar include dizziness, sweating, hunger, and confusion. Always carry a source of fast-acting sugar, such as glucose tablets or juice, in case of an emergency.
What should I do if I miss a dose of Glumetza?
If you miss a dose of Glumetza, take it as soon as you remember unless it is close to your next scheduled dose. Do not double up on doses to make up for a missed one, as this can increase the risk of side effects such as nausea or stomach upset. If unsure what to do, consult your healthcare provider for guidance.
Is Glumetza safe for long-term use?
Yes, when prescribed by a doctor, Glumetza is considered safe for long-term use. However, regular kidney function monitoring is essential, as metformin can affect kidney health, particularly in patients with existing kidney disease or those at risk for renal impairment. Your doctor may also monitor vitamin B12 levels periodically, as long-term use of metformin can sometimes lead to B12 deficiency.
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