Please note: a valid prescription is required for all prescription medication.
Abamune L is a combination antiretroviral medication containing Abacavir (600 mg) and Lamivudine (300 mg). It is used to treat HIV-1 infection by reducing viral load and slowing disease progression. This fixed-dose combination is part of nucleoside reverse transcriptase inhibitors (NRTIs), which block the virus from multiplying and help maintain immune system function.
Benefits
- Helps control HIV infection and improves immune function when combined with other antiretroviral drugs.
- Reduces the risk of HIV-related complications and increases life expectancy.
- Offers once-daily dosing, making it more convenient and improving adherence.
- Contains Lamivudine, which also provides protection against hepatitis B in co-infected patients.
Dosage
- The usual adult dose is one tablet (600 mg Abacavir + 300 mg Lamivudine) taken once daily.
- Not recommended for children under 12 years old due to fixed-dose strength.
- Tablets should be swallowed whole, with or without food.
Warnings and Precautions
- Serious allergic reactions (hypersensitivity reaction) to Abacavir can be life-threatening. Genetic testing (HLA-B*5701) is recommended before starting treatment.
- Discontinuing treatment may lead to worsening hepatitis B in co-infected patients.
- May increase the risk of heart disease, so patients with cardiovascular conditions should be closely monitored.
- Dose adjustments may be needed for patients with kidney or liver impairment.
Usage Instructions
- Take one tablet daily, at the same time every day, to maintain effectiveness.
- If a dose is missed, take it as soon as possible unless it is close to the next dose. Do not double-dose.
- If symptoms of hypersensitivity occur (fever, rash, nausea, fatigue), stop the medication immediately and seek medical help.
Storage Information
- Store at 25°C (77°F) in a dry place, away from moisture and direct sunlight.
- Keep tablets in their original sealed packaging to maintain potency.
- Protect from excessive heat or freezing temperatures.
Common Side Effects
- Mild effects: Nausea, headache, fatigue, diarrhea, dizziness.
- Serious effects (seek medical help): Signs of hypersensitivity reaction, severe liver problems, chest pain, or difficulty breathing.
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Why do I need an HLA-B*5701 test before taking Abamune L?
This test checks for a genetic marker linked to severe hypersensitivity reactions to Abacavir. If you test positive, you should avoid Abamune L.
Can Abamune L cure HIV?
No, Abamune L does not cure HIV but helps control the virus, reducing complications and improving quality of life.
What should I do if I develop a rash while taking Abamune L?
A rash can be a sign of a serious allergic reaction. If it is accompanied by fever, nausea, or breathing problems, stop taking Abamune L and seek emergency medical care.
Can I take Abamune L if I have hepatitis B?
Lamivudine in Abamune L can help suppress hepatitis B, but stopping the medication may cause severe liver flare-ups. If you have hepatitis B, consult your doctor before starting or stopping treatment.
Does Abamune L increase heart disease risk?
Studies suggest that Abacavir may slightly increase cardiovascular risks. If you have heart disease, high blood pressure, or high cholesterol, inform your doctor before taking this medication.
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