Uses of Narcan Kit Nasal Spray
Narcan (naloxone) Kit Nasal Spray is used to reverse opioid overdoses in emergency situations. These kits contain a Mask, Gloves and 2 Doses of Narcan (naloxone),a medication that rapidly restores normal breathing in someone experiencing an opioid overdose.
Precautions and Warnings
Narcan (naloxone) is a life-saving medication used to reverse opioid overdoses, but there are important precautions and warnings to consider. While it is generally safe, Narcan should only be used in situations where an opioid overdose is suspected. It is not a substitute for emergency medical care, so calling 911 immediately after administration is crucial. Because naloxone works by blocking the effects of opioids, it can trigger sudden withdrawal symptoms in individuals who are dependent on opioids. These symptoms may include agitation, nausea, vomiting, rapid heart rate, sweating, and, in severe cases, seizures. Though withdrawal itself is not usually life-threatening, it can be extremely uncomfortable and distressing for the individual.
Another important consideration is that Narcan has a temporary effect, typically lasting between 30 to 90 minutes, while some opioids can remain active in the body much longer. This means that after the naloxone wears off, overdose symptoms may return, requiring further medical intervention. If the individual does not wake up or symptoms persist after two to three minutes, a second dose of Narcan may be needed. Multiple doses may be required in cases of potent synthetic opioids like fentanyl.
Narcan should be stored at room temperature and protected from extreme heat or cold, as improper storage may reduce its effectiveness. It is also important to check the expiration date regularly, as expired naloxone may not work as intended. While Narcan is generally well-tolerated, allergic reactions are possible, though rare. Symptoms of an allergic reaction may include rash, swelling, or difficulty breathing, and medical help should be sought immediately if these occur.
Finally, Narcan should not be used as a safety net to encourage risky opioid use. It is a critical emergency tool, but overdose prevention strategies, such as avoiding mixing opioids with alcohol or other depressants and seeking treatment for opioid use disorder, are essential for long-term safety.
Dosage
The recommended dosage of Narcan® (naloxone) nasal spray for opioid overdose is one spray (4 mg) into one nostril as soon as an overdose is suspected. If the person does not wake up or their breathing does not improve within 2 to 3 minutes, an additional dose should be administered in the other nostril. Additional doses may be given every 2 to 3 minutes until the person responds or emergency medical help arrives.
For Narcan injection (used less commonly outside medical settings), the typical starting dose is 0.4 mg to 2 mg, given intramuscularly (IM), intravenously (IV), or subcutaneously (SC).** If there is no response after 2-3 minutes, additional doses can be administered. In cases of potent opioid overdoses (such as fentanyl), higher or repeated doses may be necessary.
Because Narcan’s effects last 30 to 90 minutes, but some opioids remain in the system much longer, medical attention is still required even if the person wakes up.
Side Effects
Common Side Effects:
- Withdrawal symptoms (in opioid-dependent individuals)
- Nausea or vomiting
- Sweating
- Increased heart rate (tachycardia)
- Shaking or tremors
- Increased blood pressure
