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Bupropion overdose

Post written by BFH Staff Writer on February 10, 2023
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Bupropion overdose is a serious medical emergency that requires immediate medical attention. Bupropion, also known as Wellbutrin and Zyban, is an antidepressant medication used to treat depression and other mental health conditions.

It works by increasing levels of certain chemicals in the brain that are involved in regulating moods. Unfortunately, taking too much of this drug can lead to serious side effects or even death if not treated timely.

Bupropion overdose side effects

The symptoms of bupropion overdose may include:

  • Confusion
  • Agitation
  • seizures or convulsions
  • rapid heartbeat
  • Sweating
  • Nausea and vomiting
  • Hallucinations or delusions
  • Blurred vision or double vision
  • Difficulty breathing
  • Chest pain
  • Loss of consciousness
  • Coma and even death .

In addition, it could cause irregular heartbeats called arrhythmias which can result in cardiac arrest leading to sudden death due its effect on the cardiovascular system.

If left untreated these symptoms may become worse resulting in potentially fatal consequences. So, seeking prompt medical assistance is essential when overdosing.

Bupropion overdose treatment

Treatment for a bupropion overdose may include supportive care and activated charcoal, which binds to the drug in the stomach and helps prevent its absorption. If symptoms of overdose are present, medical intervention may also be necessary, including intravenous fluids, respiratory support, and dialysis.

It is important to note that bupropion is an antidepressant and can cause suicidal thoughts and behaviors, so close monitoring may be necessary. In severe cases, a patient may need to be admitted to an intensive care unit for further treatment. Additionally, it is important to address any underlying mental health issues that may be contributing to the overdose.


In conclusion, bupropion overdose should always be considered a life-threatening emergency requiring immediate professional help because it has potential long term complications including permanent organ damage/failure, respiratory failure, cardiac arrest, stroke, coma, paralysis, neurological deficits, cognitive impairment, blindness, deafness, among others, depending on the severity.

Getting proper and timely treatment should be top priority if a suspected overdose occurs and seek help immediately. Ensure a proper evaluation diagnosis management plan to secure a safe recovery to avoid any further harm.

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