Adcirca® Tablets for Pulmonary Hypertension

Adcirca treats pulmonary arterial hypertension in adults. This page explains what it is, how it’s used, and how to request it with US delivery from Canada. It also outlines typical use, safety basics, and ways to manage costs without insurance.

What Adcirca Is and How It Works

Adcirca® contains tadalafil, a phosphodiesterase type 5 (PDE5) inhibitor used for pulmonary arterial hypertension (PAH, WHO Group 1). It helps relax blood vessels in the lungs, which can lower pulmonary pressures and improve exercise capacity. The treatment raises cyclic GMP levels by blocking PDE5, supporting better blood flow through the pulmonary circulation.

Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

This medicine is not the same as as-needed tadalafil for erectile dysfunction. It is a daily therapy for PAH and should be taken exactly as prescribed. For background on PDE5 science with tadalafil, see How Does Cialis Work.

Who It’s For

The class is indicated for adults with PAH to improve ability to exercise and delay clinical worsening when used as directed. Adcirca indications include PAH confirmed by a specialist using established criteria. People using nitrates or guanylate cyclase stimulators such as riociguat must not take this therapy due to the risk of dangerous drops in blood pressure.

Those with severe liver disease, significant hypotension, recent stroke or heart attack, certain eye conditions, or known hypersensitivity to tadalafil should avoid use. Kidney or liver impairment may require closer monitoring. A PAH expert should guide selection and follow-up; see our condition hub for context on Pulmonary Hypertension.

Dosage and Usage

Adcirca dosing for pulmonary hypertension typically follows the approved schedule: a once-daily regimen taken at the same time each day. Tablets may be taken with or without food. Swallow whole with a glass of water.

Do not combine with other PDE5 inhibitors unless directed by your prescriber. If you are prescribed antihypertensives, your clinician may monitor for symptomatic low blood pressure. For general background on dosing principles with the same active ingredient, see Cialis Dosage. Always defer to the official label and your prescriber’s instructions for individualized guidance.

Strengths and Forms

This therapy is supplied as film‑coated oral tablets for adults. Commonly published presentation is Adcirca 20 mg. Typical PAH regimens use a daily amount consistent with labeling. Availability may vary by partner pharmacy and market.

Missed Dose and Timing

If you miss a dose, take it when you remember the same day. If it is almost time for the next dose, skip the missed dose and resume your usual schedule. Do not take two doses at once to make up for a missed dose. Consistent daily timing helps maintain stable exposure.

Storage and Travel Basics

Store tablets at room temperature in a dry place, away from excess heat and moisture. Keep medication in the original, child‑resistant container with the label intact. Do not use tablets that are damaged or expired.

When traveling, carry enough supply in your hand luggage. Keep a copy of your prescription and a medication list. A pill organizer can help maintain daily timing across time zones. Security screening usually allows prescription medicines; keep labels visible. Our pharmacies use encrypted checkout, and temperature-controlled handling when required.

Benefits

This treatment may help improve exercise capacity in adults with PAH. Once‑daily administration supports adherence. Many patients appreciate that the therapy can be taken with or without food and is compatible with long‑term management plans when overseen by a PAH specialist.

Side Effects and Safety

Common Adcirca side effects can include headache, flushing, indigestion, back pain, muscle aches, nasal congestion, and dizziness. These effects are often mild to moderate and may lessen with continued use.

• Headache or flushing
• Indigestion or stomach discomfort
• Back or muscle pain
• Nasal congestion
• Dizziness
• Pain in limb

Serious risks are uncommon but require urgent care: signs of severe allergic reaction, chest pain, sudden vision or hearing changes, or a prolonged, painful erection. People with pulmonary veno‑occlusive disease may experience pulmonary edema; clinicians evaluate for this before starting therapy. Low blood pressure can occur, especially with nitrates or heavy alcohol intake.

Drug Interactions and Cautions

Nitrates of any form are contraindicated with this therapy. Guanylate cyclase stimulators such as riociguat are also contraindicated. Strong CYP3A inhibitors (for example ketoconazole, clarithromycin, ritonavir) can raise tadalafil levels; strong inducers (for example rifampin, carbamazepine, phenytoin) can lower exposure. Alpha‑blockers and other blood pressure medicines may add to hypotensive effects. Limit excessive alcohol, as it can intensify dizziness or low blood pressure.

Tell your prescriber about eye conditions including NAION risk factors, severe hepatic or renal impairment, recent cardiovascular events, and any other PDE5 inhibitor use. Do not start, stop, or change doses without medical guidance.

What to Expect Over Time

With regular daily use, many patients experience gradual improvements in exercise tolerance and symptoms under specialist care. Your clinician may monitor blood pressure, side effects, and overall clinical course. If goals are not met, they may discuss adjunctive therapies such as endothelin receptor antagonists or prostacyclin‑pathway agents. Consistent dosing, follow‑up visits, and attention to supportive measures like oxygen or diuretics when indicated can help sustain benefit.

Compare With Alternatives

Alternatives include sildenafil for PAH and the generic version of this therapy. We carry tadalafil tablets; discuss with your prescriber whether a switch is appropriate. Learn more about sildenafil’s role in PAH in our guide Sildenafil For Pulmonary Hypertension. For a discussion of PDE5 options, see Viagra And Cialis.

Product alternative offered: Tadalafil.

Pricing and Access

We aim to make therapy accessible through Canadian pharmacy partners. If you are comparing options, you can review the Adcirca price once your prescription is ready to submit. Our service supports transparent quotes and US fulfilment consistent with your prescriber’s directions. Orders Ships from Canada to US through licensed channels. If you are looking for seasonal offers, check our Promotions.

Savings CTA: You can request a quote to see current pricing and typical cash‑pay savings compared with local options. Pricing CTA: Start your order request to receive a personalized estimate based on strength, quantity, and your prescriber’s directions.

Availability and Substitutions

Supply can vary by partner pharmacy. If this product is not available, your prescriber may recommend a comparable alternative in the same class or a different PAH pathway agent. We also carry the authorized generic tadalafil in select markets; availability depends on current stock and regulatory factors. Category pages like Cardiovascular and origin filters such as Canada can help you review related options.

Patient Suitability and Cost-Saving Tips

This therapy may be suitable for adults diagnosed with PAH and evaluated for contraindications. It may be less suitable for those on nitrates, riociguat, or with severe hepatic disease. If you’re a candidate, talk with your clinician about long‑term planning, monitoring, and coordination with other PAH treatments.

Cost‑saving tips:

• Multi‑month supply: fewer refills can reduce per‑fill fees
• Generic option: discuss tadalafil tablets with your prescriber
• Refill reminders: set alerts to avoid urgent local fills
• Consolidated requests: keep strength and quantity consistent
• Travel planning: request refills ahead of trips

For additional reading on tadalafil’s mechanisms and comparisons, see What Is Cialis Used For and Sildenafil Vs Tadalafil. These explain PDE5 activity, which is the same drug class used here for PAH.

Questions to Ask Your Clinician

• Is this therapy appropriate for my PAH risk profile?
• How will we monitor blood pressure and side effects?
• Could interactions with my current medicines be an issue?
• What signs mean I should call you or seek urgent care?
• If goals are not met, what add‑on options are next?
• How should I plan for travel with a daily PAH therapy?
• Would generic tadalafil be reasonable for me?

Authoritative Sources

Refer to official labeling and regulators for complete information:

• FDA Prescribing Information
• DailyMed Monograph
• Health Canada Drug Product Database

Ready when you are. Start your request for this PAH treatment with prompt, express shipping and US shipping from Canada. This page does not replace professional medical advice; always follow your prescriber and the official label.