Delstrigo® Tablets for HIV-1 Treatment

Delstrigo® is a prescription combination tablet used to treat HIV-1 in appropriate patients. It brings three medicines together in one daily pill to help maintain a complete regimen. This page explains how it works, who may be eligible, and how you can arrange US delivery from Canada even if you are paying without insurance.

Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

What Delstrigo Is and How It Works

This medicine contains doravirine, lamivudine, and tenofovir disoproxil fumarate. As Doravirine lamivudine tenofovir disoproxil fumarate tablets, it combines a non-nucleoside reverse transcriptase inhibitor with two nucleoside analogs. Together, they help block HIV replication at different steps in the reverse transcription process. The treatment is taken once daily, with or without food, to support consistent suppression when used as directed with ongoing medical care.

It may be used in adults and certain adolescents who meet label criteria. Your clinician will confirm your history, baseline labs, and any resistance information before issuing a prescription. Review cautions about kidney health, bone health, hepatitis B, and other conditions in the sections below.

Who It’s For

Labeling supports use in adults and in eligible adolescents at or above a specified body weight, typically when starting therapy or switching from a stable, fully suppressed regimen without known resistance to its components. People with chronic hepatitis B require careful evaluation, since two components also have activity against HBV. Stopping therapy may lead to serious HBV exacerbations; monitoring is recommended.

Those with significant renal impairment may not be candidates for this fixed-dose tablet because dose adjustments are not possible for individual components. People taking strong CYP3A inducers should avoid this regimen due to reduced doravirine levels. Discuss pregnancy, breastfeeding, and other health conditions with a healthcare professional.

Dosage and Usage

Standard labeling directs one tablet by mouth once daily, with or without food. Take it at roughly the same time each day. If you have difficulty swallowing tablets, ask your clinician about practical options that remain consistent with the product label. Do not change your schedule without medical guidance.

If your prescriber determines it is appropriate for you, the fixed-dose can simplify your daily routine. The combination aligns three active ingredients in a single pill. Prescribers typically confirm viral load and other labs at regular intervals to track response and safety, especially for kidney and bone health and for those with HBV coinfection.

When asked about strengths, many patients will hear the descriptor Doravirine/lamivudine/TDF 100/300/300 mg. Always follow the exact instructions on your pharmacy label.

Strengths and Forms

The product is supplied as film-coated tablets. A commonly listed strength is Delstrigo 100/300/300 mg. Packaging usually includes bottles intended for a 30-day supply, though availability can vary by partner pharmacy. Your pharmacist will dispense according to your prescription and local regulations.

Missed Dose and Timing

If you miss a dose, take it as soon as you remember the same day. If it is almost time for your next dose, skip the missed dose and continue your regular schedule. Do not take two doses at the same time. Consistent daily use is important for maintaining suppression; consider setting reminders on your phone or calendar.

Storage and Travel Basics

Store tablets at room temperature in the original bottle, with the desiccant intact to protect from moisture. Keep the bottle closed tightly and away from excess heat. Store out of sight and reach of children and pets.

When traveling, carry the medicine in your hand luggage in the labeled container. Bring your prescription details and a copy of your medication list. Keep a small buffer of doses in case of unexpected travel changes. If security screening is a concern, a copy of your prescription can help. For specialized items we sell, we use temperature-controlled handling when required.

Benefits

This treatment consolidates three antiretroviral components in one daily tablet, which can reduce pill burden and simplify routines. It may support steady adherence by minimizing separate dosing steps. The once-daily schedule allows flexibility with meals, and the established components are well-described in official labeling for HIV care when used appropriately.

Side Effects and Safety

• Common effects: nausea, headache, dizziness, fatigue, diarrhea, abnormal dreams.
• Less common: rash or sleep changes; notify your prescriber if these persist.

Serious risks can include new or worsening kidney problems, bone mineral loss, lactic acidosis, and severe liver problems. In people with HBV coinfection, stopping therapy can cause serious exacerbations; monitoring is advised. Immune reconstitution syndrome may occur when starting or changing therapy. Seek immediate care for signs of severe abdominal pain, shortness of breath, unusual muscle pain, jaundice, or significant changes in urine output.

Drug Interactions and Cautions

Avoid strong inducers of CYP3A, such as rifampin, carbamazepine, phenytoin, and St. John’s wort, which can reduce doravirine exposure. Rifabutin also affects doravirine; this fixed-dose product cannot be dose-adjusted to compensate. Use caution with medicines that impact kidney function, including certain antivirals, aminoglycosides, or high-dose NSAIDs. Always share a full medication list, including over-the-counter products and supplements, with your clinician and pharmacist.

What to Expect Over Time

With consistent daily use and routine follow-up, many patients see steady control of viral load as part of a comprehensive HIV care plan. Your clinician may check labs periodically to monitor kidney health, bone markers, liver function, and viral suppression. If side effects occur, do not stop on your own; contact your prescriber to discuss options. Keeping a daily routine and using refill reminders can support long-term adherence.

Compare With Alternatives

Other complete regimens may be considered based on your history and resistance profile. Some patients may remain on protease inhibitor–based therapy such as Kaletra Oral Solution under specialist guidance. For prevention rather than treatment, long-acting cabotegravir, such as Apretude Injectable Suspension, serves a different role in HIV care. Your clinician can help compare options for your situation.

Pricing and Access

BorderFreeHealth offers Canadian pricing, with transparent checkout and encrypted checkout for your security. To gauge potential savings versus typical cash-pay rates, review our current listings and compare against your local quotes. If you are looking to Buy doravirine lamivudine tenofovir tablets, you can view availability and submit your prescription for review. Some patients also search to Order doravirine lamivudine TDF; your prescriber’s authorization is required before we can fulfill.

Interested in seasonal offers? See our Promotions page for current notices. For background on HIV care and testing, explore our resources on Types Of HIV Tests and Biktarvy Guide. You can also visit our condition hub at HIV or browse Antivirals.

Availability and Substitutions

Supply can vary by partner pharmacy and timing. Common packaging includes Delstrigo 30 tablets bottles. If stock is limited or a component is unsuitable for you, your prescriber may recommend an alternative regimen. Direct one-to-one substitutions are not always possible with fixed-dose products. Your clinician will choose a comparable option when appropriate.

Patient Suitability and Cost-Saving Tips

Good candidates typically have no known resistance to the included agents and have acceptable kidney function. People with chronic HBV require careful baseline testing and follow-up. Those on enzyme-inducing medicines or with significant renal impairment may need a different regimen. If cost is a concern, ask about multi-month fills, pharmacy synchronization, and refill reminders.

Some regions may offer Generic doravirine lamivudine tenofovir tablets at different times; availability depends on market approvals. We can only dispense what your prescription specifies and what is permitted by law. Consider discussing patient assistance programs and clinical priorities with your clinician to match therapy, access, and adherence.

Questions to Ask Your Clinician

• Baseline tests: What labs should I complete before starting this regimen?
• Safety checks: How will my kidney and bone health be monitored?
• HBV coinfection: What is the monitoring plan if I also have hepatitis B?
• Other medicines: Do any of my current drugs reduce effectiveness or raise risks?
• Pregnancy plans: How does this option fit with family planning and breastfeeding guidance?
• Travel and timing: What are best practices if I cross time zones?

Authoritative Sources

Manufacturer | FDA DailyMed | Health Canada DPD

Ready to proceed? Submit your prescription and start your order for US delivery from Canada with prompt, express shipping. This information is educational and not a substitute for professional medical advice.