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Livtencity® Tablets for Cytomegalovirus (CMV)
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Applies to all products originating from Canada. Maximum allowable quantity equal to a 90-day supply per single order.
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$18,990.99
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Livtencity is a prescription antiviral used after transplant when CMV persists despite prior therapy. We offer access with US delivery from Canada so you can compare Canadian pricing. You can review options and typical costs without insurance before you add this medicine to your cart.
What Livtencity Is and How It Works
Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.
Livtencity® contains maribavir, a CMV UL97 protein kinase inhibitor. Livtencity maribavir blocks a viral enzyme needed for CMV replication and maturation. It is indicated for post-transplant CMV infection or disease that is refractory to prior antiviral treatments, with or without genotypic resistance. The treatment is taken by mouth and may be used when previous options such as ganciclovir, valganciclovir, foscarnet, or cidofovir have not worked or were not tolerated. It is not approved for CMV prevention.
Per the label, this medicine can be taken with or without food. Your clinician will monitor CMV DNA levels and adjust care based on response and safety labs.
Who It’s For
This therapy is for adults and certain adolescents after hematopoietic stem cell or solid organ transplant who have CMV infection that did not respond to other antivirals. Livtencity indication includes refractory CMV with or without documented resistance. People with known hypersensitivity to maribavir should not use it. Those who are pregnant, planning pregnancy, or breastfeeding should discuss risks and benefits with a clinician due to limited human data.
Use caution with severe hepatic impairment or when significant drug interactions are present. This treatment is not a substitute for CMV prophylaxis in transplant care.
Dosage and Usage
The labeled adult regimen is 400 mg by mouth twice daily. Tablets are typically swallowed whole and taken at consistent times each day. If your clinician provides a different schedule due to your clinical status, follow their guidance. See the official label for detailed directions and administration options. Refer to Livtencity prescribing information for the complete dosing instructions and monitoring recommendations.
General administration tips:
- Take doses about 12 hours apart when possible.
- Take with or without food as directed.
- Keep a daily reminder to support adherence.
- Do not stop early without discussing it with your prescriber.
Strengths and Forms
This medicine is supplied as film-coated oral tablets. Commonly available strength includes 200 mg tablets. Availability can vary by manufacturer packaging and market.
Missed Dose and Timing
If you miss a dose, take it when you remember unless it is close to the next scheduled dose. If it is almost time for the next dose, skip the missed one and resume your regular schedule. Do not take two doses at once. If vomiting occurs soon after a dose, consult the official label or your clinician for next steps, as guidance may depend on timing.
Storage and Travel Basics
Store tablets at room temperature in the original container, protected from excess moisture. Keep out of reach of children and pets. When you travel, carry the medicine in your hand luggage with your prescription details. Use a pill organizer only if you can keep the tablets dry and labeled. For longer trips, bring enough supply and a copy of your prescription for screening.
If customs documentation is requested, have your pharmacy receipt and prescriber information available. For questions about packaging, ask our team before you order so you can plan your travel and storage accordingly.
Benefits
This antiviral class targets CMV in a different way than DNA polymerase inhibitors. It can offer an oral option when prior therapies did not achieve adequate response or were limited by tolerability. Twice-daily dosing and no routine laboratory dose-adjustment requirements for mild to moderate kidney or liver impairment may support continuity of care when monitoring is complex.
Side Effects and Safety
- Taste disturbance or “metallic” taste
- Nausea or upset stomach
- Diarrhea
- Vomiting
- Fatigue or headache
Serious risks can include allergic reactions, significant changes in liver tests, or interactions that raise levels of other transplant medicines. Contact your clinician right away for signs of severe rash, swelling of the face or throat, trouble breathing, or persistent vomiting. Livtencity side effects are fully detailed in the FDA-approved label and patient information leaflet.
Learn about allergic swelling and warning signs in our guide What Is Angioedema.
Drug Interactions and Cautions
Important interactions include:
- Calcineurin and mTOR inhibitors: tacrolimus, cyclosporine, sirolimus. Levels may rise; careful monitoring is needed.
- Strong enzyme inducers: rifampin and similar agents may lower maribavir exposure.
- Antagonism with ganciclovir or valganciclovir: coadministration is not recommended.
- Drugs transported by P-gp or metabolized by CYP3A: clinical monitoring may be required.
Transplant recipients often take multiple therapies. Your team may check drug levels more frequently when this antiviral is started or stopped. For context on transplant immunosuppressants, see Rapamune.
For more options by treatment class, explore our category pages: Cytomegalovirus CMV Infection, Antivirals, and Made In Canada.
What to Expect Over Time
Your clinician will monitor CMV DNA levels and your clinical status during therapy. Many patients notice taste changes within days, which often lessen with continued use. Gastrointestinal symptoms can occur early and may be manageable with supportive care. Improvement in laboratory markers typically guides decisions to continue or stop the treatment. Keep all scheduled lab checks and report any unusual symptoms promptly.
Compare With Alternatives
Other approved options for refractory or resistant CMV include ganciclovir or valganciclovir, foscarnet, and cidofovir, depending on prior response, resistance patterns, and organ function. Each option has distinct safety considerations such as bone marrow effects or kidney effects. Your transplant team will select therapy based on your history, resistance results, and tolerability.
Pricing and Access
We list transparent Canadian pricing with US shipping from Canada for qualified prescriptions. You can compare options and request a refill through your account. If you pay cash, you can check the Livtencity cash price and discuss alternatives with your clinician if needed. For reference questions around strength-based options, many users search for Maribavir 200 mg tablets price to understand market ranges.
Looking for seasonal offers or manufacturer support links? Visit our Promotions page; availability varies.
You can also browse related condition pages for context and therapy class comparisons: Cytomegalovirus CMV Infection and Antivirals.
Availability and Substitutions
If this item is temporarily unavailable, your prescriber may recommend an appropriate alternative based on your resistance profile and medical history. We cannot guarantee stock dates. Please upload your prescription so our team can verify options with your clinician if substitution is requested.
Patient Suitability and Cost-Saving Tips
This therapy may suit transplant recipients with refractory CMV when benefits outweigh risks and interactions can be managed. It may not suit those with known hypersensitivity, unmanageable interactions, or those who cannot complete the required monitoring.
- Multi-month fills: ask your prescriber if a longer supply is appropriate.
- Coordinated refills: set reminders to avoid treatment gaps.
- Lab planning: schedule monitoring to align with your dosing cycle.
- Travel-ready: keep a copy of your prescription when you travel.
- Budget planning: review pricing and discuss alternatives early if needed.
Questions to Ask Your Clinician
- Is this antiviral appropriate for my CMV strain and resistance testing?
- How will my immunosuppressant levels be monitored during therapy?
- What signs mean I should contact the transplant team right away?
- How long should I stay on treatment, and what labs decide this?
- Which medicines, herbs, or supplements should I stop or avoid?
- What strategies can reduce taste changes or stomach upset?
Authoritative Sources
See official references for complete prescribing details and safety information. For regulatory context, review Maribavir FDA approval materials and product monographs.
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Disclaimer: This page is educational and not a substitute for professional medical advice. Always follow your clinician’s instructions and the official label.
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What is Livtencity used for after transplant?
Livtencity is an oral antiviral containing maribavir. It is approved to treat cytomegalovirus (CMV) infection or disease in transplant recipients when the virus has not responded to prior CMV therapy, with or without documented resistance. It is not indicated for CMV prevention. Your clinician will decide if it fits your situation based on your treatment history, resistance results, and overall health, and will monitor viral load and safety labs during therapy.
How long do people usually stay on this antiviral?
Per the approved label, dosing is typically twice daily and treatment often continues for about eight weeks. Your duration may differ based on clinical response, CMV DNA trends, and tolerability. The transplant team will check labs during therapy and may extend or stop treatment depending on your progress. Do not change your schedule on your own. Ask your prescriber how long they expect you to continue.
Can I take maribavir with food or acid-reducing medicines?
Tablets may be taken with or without food. Always tell your clinician about all medicines you use, including acid-reducing agents and supplements. Some drugs strongly induce or inhibit enzymes and transporters and may change maribavir levels. Your clinician will review your full list to reduce interaction risks and decide whether any adjustments or additional monitoring are needed.
Does it interact with tacrolimus, cyclosporine, or sirolimus?
Yes. Maribavir can increase blood levels of transplant immunosuppressants such as tacrolimus, cyclosporine, and sirolimus. Your team will typically check trough levels more often when starting or stopping therapy and adjust those medicines if necessary. Report symptoms of toxicity such as tremor, headaches, or kidney changes promptly. Do not change doses on your own without transplant team guidance.
What if I miss a dose or vomit after taking it?
If you miss a dose, take it when remembered unless it is close to the next scheduled dose, in which case skip the missed dose. Do not double up. If you vomit soon after taking a tablet, the next step can depend on timing; check the official label or call your clinician for advice. Keeping a daily alarm and a small backup dose with you may help support adherence.
Is Livtencity safe during pregnancy or breastfeeding?
Human data are limited. Animal data may not predict human outcomes. If you are pregnant, planning to become pregnant, or breastfeeding, discuss risks and benefits with your clinician before starting therapy. They will consider your CMV severity, available alternatives, and monitoring needs. Do not start or stop the medicine without professional guidance.
Can children or adolescents use maribavir?
The approval includes certain pediatric patients after transplant who meet age and weight thresholds, alongside adults. Your clinician will determine eligibility based on the official label, body weight, organ function, and prior antiviral exposure. Dosing, safety monitoring, and drug interaction checks are essential. Always follow your prescriber’s directions and keep all lab appointments during therapy.
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