Persantine® Injection for Myocardial Perfusion Imaging

Persantine is dipyridamole used for pharmacologic stress testing and to reduce clot risk in specific cases. This page explains how the injection is used, key safety points, and ways to access care with US delivery from Canada, including Persantine without insurance.

What Persantine Is and How It Works

Persantine® contains dipyridamole, a vasodilator and antiplatelet medicine. In nuclear cardiology, it increases coronary blood flow in healthy vessels, helping clinicians detect perfusion differences during myocardial imaging when exercise is not possible. In tablet form, the drug acts on platelets to reduce their sticking together, supporting prevention of thromboembolic complications in select patients.

Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

Dipyridamole inhibits adenosine uptake and phosphodiesterase activity. These actions raise endogenous adenosine and cyclic nucleotides, which can relax vascular smooth muscle and reduce platelet aggregation. Effects are dose dependent and reversible. Caffeine and theophylline can blunt the pharmacologic stress response by antagonizing adenosine effects.

You can Buy Persantine online through BorderFreeHealth.com once your prescriber sends a valid prescription. Our team coordinates verification and supports your order through secure checkout.

Who It’s For

The injection is used as a coronary vasodilator for myocardial perfusion imaging in adults who cannot complete adequate exercise stress. Testing occurs in supervised settings with continuous monitoring and access to reversal agents. For prevention of thromboembolic complications after cardiac valve replacement, the oral form may be used with warfarin under clinician oversight according to labeling.

This treatment may not suit people with uncontrolled bronchospasm, severe hypotension, unstable angina, recent myocardial infarction, or significant conduction abnormalities without a pacemaker. Patients with severe aortic stenosis or decompensated heart failure may require alternative stress strategies. Those with bleeding disorders or active bleeding require careful evaluation before antiplatelet therapy.

Dosage and Usage

For pharmacologic stress testing, the medicine is given intravenously in a controlled setting using a weight-based infusion over several minutes per the official label. Vital signs and electrocardiographic changes are monitored during and after administration. A methylxanthine such as aminophylline may be used by clinicians to reverse persistent adverse effects if needed. Patients are usually advised to avoid caffeine and certain bronchodilators before testing, because these can reduce the vasodilator response.

For oral antiplatelet use, prescribers typically follow labeled schedules divided through the day. Tablets are taken with a full glass of water and may be taken with food to limit stomach upset. Do not change your dose or schedule without talking to your prescriber. If dosing differs from these high‑level points, follow the exact instructions on your prescription label.

Infusion should be administered through appropriate venous access with resuscitation equipment available. Staff confirm contraindications, check concurrent medicines, and review caffeine avoidance before the appointment. After imaging, you will be observed until stable and cleared by the care team.

Strengths and Forms

Availability can vary by country and manufacturer. Common presentations include:

• Injection ampoules or vials for intravenous use during imaging
• Tablets in several strengths for adjunct antiplatelet therapy

Published tablet strengths often include 25 mg, 50 mg, and 75 mg. One commonly available injection concentration is listed on the official label; check your specific package for details. Persantine tablets and injectable products may not always be stocked at the same time.

Missed Dose and Timing

Injection timing is scheduled by your imaging center; missed or rescheduled appointments should be coordinated with the facility. If you use the tablet form and miss a dose, take it when remembered unless it is near the next dose. If it is close, skip the missed dose. Do not double up. When unsure, call your prescriber or pharmacist.

Storage and Travel Basics

Keep ampoules or vials in original packaging, away from moisture and excessive heat. Protect from light as directed by the label. Do not freeze injectable solutions. Store tablets in a tightly closed container, away from children and pets. When traveling, keep the medicine in your carry‑on with a copy of your prescription and clinic instructions. Pharmacies use temperature-controlled handling when required.

If your imaging center provides the drug on site, follow their storage and transport guidance. Do not use the injection if the solution is discolored, contains particles, or the container is damaged. Dispose of opened containers as instructed by your healthcare professional.

Benefits

This pharmacologic stress option allows cardiac perfusion imaging when treadmill exercise is not possible or contraindicated. It can help unmask perfusion differences for diagnostic interpretation. In antiplatelet use, the class can support reduced clot risk alongside warfarin after certain valve surgeries, following the approved indication. Using a pharmacologic stress agent in a supervised setting can standardize testing conditions and minimize exertional risk.

Patients and clinicians may also appreciate that the medicine’s effects are reversible. Caffeine abstinence and careful monitoring help maintain predictable responses during testing.

Side Effects and Safety

• Headache or dizziness
• Flushing or warmth
• Nausea or stomach discomfort
• Chest discomfort or shortness of breath
• Palpitations or fatigue

Serious or rare events can include severe hypotension, bronchospasm, atrioventricular block, or ischemia. In tablet use, bleeding risk may increase when combined with anticoagulants or antiplatelet drugs. Seek urgent care for chest pain, severe breathing difficulty, fainting, or signs of bleeding. Testing should occur in facilities with emergency support and reversal agents available.

Drug Interactions and Cautions

Adenosine antagonists such as caffeine, theophylline, and aminophylline may diminish the vasodilator effect. Antihypertensives or nitrates can increase the chance of low blood pressure. Anticoagulants, antiplatelets, and certain NSAIDs can raise bleeding risk when the tablet form is used. Dipyridamole can potentiate adenosine’s effects, so the dose of adenosine given for other purposes may require adjustment by clinicians.

Use caution with obstructive lung disease, unstable cardiovascular status, or conduction disease without pacing. Tell your prescriber about all medicines, supplements, and caffeine use. Review pregnancy or breastfeeding considerations with your clinician before starting therapy.

What to Expect Over Time

During imaging, you may feel flushing, warmth, or lightheadedness that typically resolve after the test. The care team will observe you until stable and ready for discharge. For those prescribed the tablets, benefits depend on consistent, long‑term use as instructed. Keep scheduled follow‑ups to review response, side effects, and any changes in your medicine list. Report new symptoms promptly, especially bleeding or chest pain.

To support adherence, use reminders, pill organizers, or pharmacy synchronization programs. If your regimen changes, ask your pharmacist to update labels and review interaction checks.

Compare With Alternatives

Clinicians may consider other pharmacologic stress agents such as regadenoson, adenosine, or dobutamine, depending on patient characteristics and test goals. For antiplatelet prevention, alternatives include clopidogrel or aspirin‑dipyridamole combinations when appropriate. For broader cardiovascular risk reduction, statins or non‑statin lipid‑lowering therapies may be part of a comprehensive plan. Consider discussing Pravastatin Sodium or Leqvio with your clinician if lipid management is also indicated.

To explore related treatments, browse our Cardiovascular collection or learn about antiplatelet therapy in our guide What Is Brilinta Used For.

You can Order Persantine once your prescriber sends a valid prescription to BorderFreeHealth.com.

Pricing and Access

We source Canadian pharmacy inventory and coordinate verified prescriptions for U.S. patients. If you are comparing options, review the Persantine price on our product page and consider the total value, including professional verification and support. Self-pay totals vary by strength, quantity, and pack type. You can also compare Dipyridamole cost with the brand listing when a generic is available.

Pricing reflects Canadian supply, with US delivery from Canada handled by our partners. See the product page for current availability and add it to your cart when your prescription is ready. If you are looking for seasonal offers, visit our Promotions page for limited updates.

For help choosing related medicines, our articles such as Lisinopril 10 Mg can provide context, and category pages like Blood Clot DVT PE can guide browsing.

Availability and Substitutions

Stock levels can vary by form and strength. If this injectable presentation is temporarily unavailable, your prescriber may recommend an alternative stress agent or adjust the test plan. For antiplatelet needs, the clinician may suggest a different therapy based on your history and concurrent medicines. Pharmacy teams can assist with substitution discussions after receiving your prescription.

Patient Suitability and Cost-Saving Tips

Good candidates for pharmacologic stress are adults unable to perform adequate exercise or those with interfering orthopedic or neurologic limitations. People with active bronchospasm, severe conduction disease without pacing, or unstable cardiac status may need another approach. For tablet therapy, suitable candidates are those meeting labeled criteria for prevention after valve replacement under specialist care.

To save on therapy, ask your prescriber if generic options fit your plan, such as Generic dipyridamole tablets when appropriate. Consider multi‑month fills to reduce per‑fill fees, and set refill reminders a week before you run out. Review your full medication list to remove duplicates and streamline therapy. To learn how injectable clinic medicines are handled, see products like Toradol IM Ampoules and tablet therapies like Sitagliptin for context on formats and handling.

If your prescriber changes strength or form, message our support before checkout so the order matches your prescription. Keep your contact details current to avoid delays if your care team needs to confirm information.

Questions to Ask Your Clinician

• Is pharmacologic stress appropriate for my cardiac history?
• Should I avoid caffeine or certain inhalers before testing?
• What signs during the test require stopping early?
• How will aminophylline or other reversal agents be used?
• If tablets are prescribed, what bleeding signs should I watch for?
• Which medicines or supplements could interfere with this therapy?
• How often should we reassess my cardiovascular risk plan?

Authoritative Sources

FDA DailyMed: Dipyridamole Injection

FDA DailyMed: Dipyridamole Tablets

Health Canada DPD: Persantine

Ready to proceed? Add your prescription and checkout for prompt, express shipping with US shipping from Canada. This information is educational and not a substitute for medical advice; follow your prescriber’s guidance.