Taltz® Injection for Plaque Psoriasis

Taltz is a prescription biologic that treats plaque psoriasis and related arthritis. It targets a specific immune signal to calm inflammation and help clear skin. This page explains how it works, typical use, and how to access it with US delivery from Canada, including options if paying without insurance.

What Taltz Is and How It Works

Taltz® contains ixekizumab, a monoclonal antibody that binds interleukin‑17A. By blocking IL‑17A, it helps reduce inflammatory activity in skin and joints. Ixekizumab injection belongs to the IL‑17A inhibitor class, used for several immune‑mediated conditions.

Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

This medicine is approved for adults with moderate to severe plaque psoriasis. It is also indicated for active psoriatic arthritis, ankylosing spondylitis, and non‑radiographic axial spondyloarthritis. The treatment is given by subcutaneous injection using an autoinjector or a prefilled syringe.

Who It’s For

Approved uses include moderate to severe plaque psoriasis in adults who are candidates for phototherapy or systemic therapy. It also treats active psoriatic arthritis and axial spondyloarthritis, including ankylosing spondylitis. Learn more about these conditions in our categories for Psoriasis and Psoriatic Arthritis.

Taltz for psoriatic arthritis may be used alone or with non‑biologic disease‑modifying drugs. Patients with active or chronic infections should avoid starting therapy until infections are controlled. Screening for tuberculosis is recommended before beginning treatment. Use caution if there is a history of inflammatory bowel disease, as symptoms may worsen. Discuss pregnancy and breastfeeding plans with a healthcare professional.

For spinal arthritis, clinicians may consider this option in Ankylosing Spondylitis or other axial disease when appropriate.

Dosage and Usage

Follow the Patient Information and your prescriber’s instructions. Many adults with plaque psoriasis start with a higher first dose, then move to injections at regular intervals for several months, followed by maintenance injections about once monthly. People with psoriatic arthritis may receive a similar start, then continue at a monthly schedule. For ankylosing spondylitis and non‑radiographic axial spondyloarthritis, maintenance dosing is generally monthly after the initial dose.

Ixekizumab 80 mg/mL injection is administered under the skin of the thigh, abdomen, or upper arm. Rotate injection sites and avoid areas that are tender, bruised, or scarred. Do not attempt to change your schedule or stop therapy without consulting the prescriber.

If a clinic visit is planned, bring the device as directed. Review the Medication Guide and Instructions for Use included with your device before the first dose.

Strengths and Forms

Availability may vary by supplier. Common presentations include:

• Ixekizumab 80 mg/mL autoinjector
• Prefilled syringe for subcutaneous use

Device types are designed for single‑patient use only. Packaging may differ by manufacturer lot or country of origin.

Missed Dose and Timing

If a dose is missed, take it as soon as remembered, then resume the regular schedule. If it is close to the next planned dose, ask the prescriber which day to use going forward. Do not double up to make up a missed injection. Try to use a calendar or reminder to keep the interval consistent.

Storage and Travel Basics

Store this medicine in the refrigerator in the original carton to protect it from light. Do not freeze or shake. If needed for travel, the device may be kept at room temperature for a limited period as described in the official Instructions for Use; once kept at room temperature, do not return it to the refrigerator. Keep out of reach of children.

For trips, use an insulated pouch and bring a copy of your prescription. Pack extra supplies for delays. Airlines may request documentation for injectable medicines and sharps. We support temperature-controlled handling when required.

Pen Handling and Sharps Disposal

Before injecting, allow the device to reach room temperature as directed in the Instructions for Use. Wash hands, clean the site with an alcohol swab, and follow the device steps. After the dose, place the used autoinjector or syringe into an FDA‑cleared sharps container. Do not throw sharps in household trash. When the container is about three‑quarters full, follow local guidance for disposal.

Benefits

As an IL‑17A inhibitor, this treatment targets a key inflammatory pathway. Many patients see skin improvement and reduced joint symptoms when used as directed. Taltz injection offers at‑home dosing with autoinjector support materials and a consistent maintenance schedule.

Side Effects and Safety

• Injection site reactions
• Upper respiratory symptoms, such as nasal congestion
• Nausea
• Fungal skin infections
• Headache

Serious risks include severe infections, tuberculosis reactivation, hypersensitivity reactions, and potential worsening of inflammatory bowel disease in susceptible patients. Seek urgent care for signs of severe allergic reaction or infection, such as high fever, shortness of breath, or swelling of the face or throat. This medicine may increase infection risk when used with other immunosuppressants.

Drug Interactions and Cautions

Avoid live vaccines during treatment. Tell the prescriber about all prescription drugs, over‑the‑counter medicines, and supplements. Using multiple immunomodulators together can raise infection risk. Screening for tuberculosis is commonly recommended before starting therapy. Report gastrointestinal symptoms promptly if there is a history of Crohn’s disease or ulcerative colitis. For pain related to arthritis, non‑biologic options may be considered; see our overview in Celebrex And Arthritis. Always rely on the official label for the most current safety information.

What to Expect Over Time

Some patients notice early changes in skin or joints during the initial weeks, followed by steadier progress with maintenance. Ixekizumab psoriatic arthritis treatment may help reduce tender and swollen joints over time. Individual response varies. Keeping a symptom journal and attending follow‑ups can help track progress and guide decisions. If goals are not met, prescribers may adjust plans or consider alternatives.

Compare With Alternatives

Other approved biologics for these conditions include IL‑17 and IL‑23 pathway agents. For example, Cosentyx is another IL‑17A inhibitor used for similar indications, and Skyrizi targets IL‑23 for plaque psoriasis and psoriatic arthritis. Choice depends on diagnosis, comorbidities, formulation preferences, and prescriber guidance.

Pricing and Access

Canadian suppliers may offer lower list prices compared with many U.S. cash options. Taltz price varies by device type and fill length. To explore coupon‑based options, see Promotions. We provide transparent information so you can review options and place an order that fits your needs.

Ships from Canada to US with clear steps for checkout and refill support. For broader options in related conditions, visit Rheumatology.

Availability and Substitutions

Supply can vary by manufacturer lot and distributor. If the requested presentation is unavailable, a prescriber may recommend a comparable alternative in the same class, or a different mechanism that suits the diagnosis. We do not provide dates for restocks.

Patient Suitability and Cost-Saving Tips

This therapy may be appropriate for adults with moderate to severe plaque psoriasis, active psoriatic arthritis, or axial spondyloarthritis when systemic treatment is indicated. It may not suit patients with uncontrolled infections or those who require live vaccines imminently. TB screening is recommended before treatment initiation.

To reduce overall costs, consider multi‑month supplies when appropriate, which may lower per‑fill overhead. Set refill reminders so you do not miss maintenance doses. Ask the prescriber whether specialty support programs or manufacturer resources are available. For education on conditions, visit Axial Spondyloarthritis and browse Psoriasis resources.

Questions to Ask Your Clinician

• Diagnosis fit: Is this class appropriate for my skin or joint disease?
• TB screening: What tests are needed before starting?
• Vaccines: Which immunizations should be updated before treatment?
• Monitoring: What symptoms or labs should be tracked during therapy?
• Combinations: Can I continue current arthritis medicines safely?
• Device choice: Autoinjector or syringe, and why?
• Travel: How should I store and transport doses for trips?

Authoritative Sources

• FDA Prescribing Information
• DailyMed: Ixekizumab
• Health Canada Drug Product Database

Ready to get started? Place your order with prompt, express shipping and US shipping from Canada. This information is not a substitute for professional medical advice; always follow your prescriber’s directions and the official label.