Velphoro

Velphoro (sucroferric oxyhydroxide) is a phosphate binder used to control serum phosphorus levels in adults with chronic kidney disease (CKD) who are on dialysis. It works by binding to dietary phosphate in the gastrointestinal tract, preventing its absorption into the bloodstream. Velphoro is a chewable tablet and should be taken with meals.

Benefits

• Effectively reduces high phosphate levels in patients with CKD on dialysis
• Helps maintain healthy mineral balance in the body
• Reduces risk of bone and cardiovascular complications related to hyperphosphatemia
• Chewable formulation for convenient administration
• Does not contain calcium or aluminum, reducing risk of related complications

Dosage

• Starting dose: 500 mg (1 tablet) chewed with each meal, three times daily
• Dose may be adjusted based on serum phosphorus levels
• Maximum dose: 3,000 mg per day (6 tablets)
• Tablets must be chewed thoroughly and should not be swallowed whole
• Should be taken with food to ensure effectiveness

Warnings and Precautions

• May cause dark-colored stools due to iron content; this is normal and not harmful
• Not suitable for patients with iron overload disorders (e.g., hemochromatosis)
• Use with caution in patients with gastrointestinal disorders or recent GI surgery
• Can interact with other oral medications; spacing doses may be necessary
• Not studied in children or patients not on dialysis
• Iron absorption is minimal but should be monitored in patients on long-term therapy

Usage Instructions

• Take Velphoro with meals, three times daily
• Chew tablets thoroughly before swallowing; do not swallow whole
• If a dose is missed, take it with the next meal
• Do not take more than the prescribed dose without consulting a healthcare provider
• Continue taking as directed, even if you feel well

Storage Information

• Store at room temperature between 20°C and 25°C (68°F and 77°F)
• Protect from moisture and light
• Keep out of reach of children

Common Side Effects

• Diarrhea
• Discolored (dark) stools
• Nausea or abdominal discomfort
• Constipation
• Flatulence
• More serious side effects may include severe gastrointestinal symptoms or iron accumulation in rare cases