Velphoro® Chewable Tablets for Hyperphosphatemia

Velphoro® is a prescription phosphate binder used to control high phosphorus in adults with chronic kidney disease on dialysis. This page explains how it works, how to take it, and how to access it with US shipping from Canada, plus what to consider about Velphoro price without insurance.

What Velphoro Is and How It Works

Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

Velphoro is the brand name for sucroferric oxyhydroxide, a non-calcium, iron-based phosphate binder. It binds dietary phosphate in the gut, forming insoluble complexes. Those complexes are not absorbed and are passed in the stool. Lower phosphate from meals can help reduce persistently high serum phosphorus in people on dialysis.

As a class, binders work only when taken with food. The tablet is chewable and should be chewed thoroughly. Swallowing whole is not advised. Stools may appear darker due to iron content. If diarrhea persists or becomes severe, contact your prescriber.

Many patients and clinicians use the phrase Velphoro phosphate binder to distinguish it from calcium-based options. This medicine is not a replacement for diet guidance. Follow any renal diet instructions provided by your care team.

Who It’s For

This treatment is indicated to control serum phosphorus in adults with chronic kidney disease on hemodialysis or peritoneal dialysis. Use in patients not on dialysis has not been established. Pediatric use has not been established.

Do not use if you have a known hypersensitivity to sucroferric oxyhydroxide or any component of the tablet. Although systemic iron absorption is low, people with iron overload disorders should discuss risks and monitoring with a healthcare professional. Your prescriber may check iron parameters as clinically indicated.

Dosage and Usage

Follow the directions on your prescription label. A common starting schedule is one tablet with each main meal, and your prescriber may adjust week by week. Take doses only with food. Chew each tablet completely; do not swallow whole. If swallowing or chewing is difficult, ask your clinician about practical techniques.

Your dose may change based on serum phosphorus results and how well you tolerate the medicine. Do not change your dose on your own. If other oral medicines are part of your regimen, your prescriber may advise spacing to avoid binding interactions. When uncertain, defer to the official label.

Strengths and Forms

Velphoro 500 mg chewable tablets are the commonly available presentation. Availability may vary by partner pharmacy and packaging size.

Missed Dose and Timing

If you miss a dose, take the next dose with your next meal. Do not take two doses at once or extra tablets between meals. Keep your meal-time routine consistent to support steady control of phosphorus.

Storage and Travel Basics

Store the tablets at room temperature and keep the bottle tightly closed. Protect from excessive moisture. Keep out of reach of children and pets. When traveling, carry the labeled container and a copy of your prescription. A simple medication checklist can help you avoid missed meal-time doses. For flights, keep medicines in your carry-on and consider bringing a small organizer for meals away from home.

Benefits

This therapy can help reduce phosphorus absorbed from meals, supporting targets set by your care team. The chewable format may be more convenient for some patients than large, non-chewable tablets. As an iron-based binder, it does not add calcium, which can be helpful for people who must limit calcium loads.

Side Effects and Safety

• Diarrhea or loose stools
• Nausea or vomiting
• Dark stools
• Abdominal discomfort
• Tooth or tongue discoloration (usually temporary)

Serious reactions are uncommon. Stop the medicine and seek care for signs of hypersensitivity such as rash, swelling, or breathing difficulty. Diarrhea that is persistent or severe may require dose adjustment or an alternative binder. Your prescriber may periodically review iron indices and overall mineral bone parameters.

Drug Interactions and Cautions

Iron-based binders can reduce absorption of certain oral drugs. Levothyroxine should not be taken at the same time; your clinician may advise a separation interval. Some antibiotics, such as doxycycline, may also require spacing or avoidance with this binder. Discuss all prescription and nonprescription products, including supplements and antacids. If you take multiple medicines, consider using a spacing plan created by your prescriber or pharmacist.

Tell your healthcare professional about pregnancy or breastfeeding plans. Report any GI bleeding or a history of significant GI disorders. If you follow a restricted diet, continue dietary counseling alongside this treatment.

What to Expect Over Time

With regular, meal-time dosing and diet guidance, serum phosphorus may trend toward targets set by your clinician. Your dose may be adjusted based on lab results and tolerance. Many people notice darker stools early on; this is expected with iron-based binders. Diarrhea often improves after the first days or with dose changes. Consistency matters, so aligning doses with the same meals each day can help maintain adherence.

If you miss doses frequently, consider simple reminders. Linking doses to a specific meal routine, or keeping a small supply in a work or travel bag, can improve follow-through. Continue regular lab monitoring as directed by your care team.

Compare With Alternatives

Approved alternatives include sevelamer carbonate, calcium acetate, and ferric citrate. Sevelamer is non-absorbable and calcium-free. Calcium acetate adds calcium and may be used when additional calcium is acceptable. Ferric citrate is iron-based and may increase iron stores. Your clinician will match a binder to your labs, calcium balance, and tolerance.

Pricing and Access

We list transparent options so you can review Velphoro price and compare fill quantities. You can also explore Canadian pricing on this product with Ships from Canada to US fulfillment. If you are looking to Buy Velphoro online, you can start by selecting your quantity and sending us your prescription.

Have a coupon from your prescriber or support program? See Promotions for any current site offers. We support encrypted checkout and coordination with your prescriber when required.

For related condition context, you can browse Hyperphosphatemia and see Other Products that may support your overall regimen.

Availability and Substitutions

Stock can vary. If a specific pack size is unavailable, your prescriber may recommend an alternative binder or an interim quantity. We cannot advise on substitutions; final decisions rest with your clinician and dispensing pharmacist.

Patient Suitability and Cost-Saving Tips

This treatment may suit adults on dialysis who need a non-calcium option. It may not suit those with a history of intolerance to iron-based binders or certain GI conditions. If you have complex regimens, ask for a spacing plan to reduce interaction risks.

• Multi-month fills: Fewer refills can lower out-of-pocket cost.
• Align with meals: Keep a small supply in your dialysis bag.
• Refill reminders: Set calendar alerts a week before you run low.
• Diet support: Keep dietitian guidance alongside this medicine.
• Review labs: Share phosphorus trends at each visit.

For budgeting, you can compare Velphoro cost across quantities and look at the cash price beside your insurance options. If costs remain high, ask your prescriber about alternative binders or manufacturer support programs where applicable.

Questions to Ask Your Clinician

• How should I time this binder with my other oral medicines?
• What is my target phosphorus range and when will we recheck labs?
• What signs mean I should call you about side effects?
• Should I separate this from levothyroxine or certain antibiotics?
• Is my current diet plan aligned with this therapy?
• Can we consider a 90-day fill to simplify refills?

Authoritative Sources

FDA DailyMed LabelHealth Canada Product MonographManufacturer Information

Related reading and options: Explore Hyperphosphatemia, browse Canada Origin, review Other Products, and consider adjunct therapies such as Captopril, Sitagliptin, Ozempic®, and Ciprofloxacin. For context, see Types Of Insulin and Lisinopril Guide. If you are searching for deals, check Promotions.

Ready to proceed? Start your order for your prescription with prompt, express shipping and US delivery from Canada. This information is educational and not a substitute for professional medical advice.