Apixaban

Apixaban is a prescription medication used to prevent and treat blood clots in people at risk of conditions such as deep vein thrombosis (DVT), pulmonary embolism (PE), and stroke in atrial fibrillation (AFib). It belongs to a class of drugs called anticoagulants, often referred to as blood thinners, which help prevent harmful clots from forming in the blood vessels. Apixaban is available in tablet form and is taken by mouth.

Benefits

• Reduces the risk of stroke in people with atrial fibrillation not caused by a heart valve issue
• Prevents blood clots following hip or knee replacement surgery
• Treats existing blood clots in the legs (DVT) and lungs (PE)
• Lowers the risk of recurrent DVT and PE after initial treatment
• Offers a convenient oral option without routine blood testing in most cases

Dosage

• The typical dose for stroke prevention in atrial fibrillation is 5 mg twice daily, but some people may be prescribed 2.5 mg twice daily if they meet certain criteria (e.g., age 80 or older, low body weight, or kidney issues)
• For treating DVT or PE, 10 mg twice daily for 7 days, then 5 mg twice daily
• For preventing recurrent clots, 2.5 mg twice daily after at least 6 months of initial treatment
• Take Apixaban at the same time each day, with or without food
• Never adjust your dose without speaking to your doctor

Warnings and Precautions

• Apixaban increases the risk of bleeding, which may be serious or life-threatening
• Inform your doctor if you have kidney or liver disease, a history of bleeding problems, or recent surgery
• Let all healthcare providers know you are taking Apixaban, especially before any surgical or dental procedures
• Avoid activities that may increase your risk of injury or bleeding
• Do not stop taking Apixaban suddenly without your doctor’s advice, as this may increase the risk of stroke or blood clots
• Tell your doctor about all medicines you take, including over-the-counter drugs and supplements, as some may interact with Apixaban

Usage Instructions

• Take Apixaban by mouth with a glass of water, at the same times each day
• If you miss a dose, take it as soon as you remember. If it is close to the time of your next dose, skip the missed dose and continue your regular schedule. Do not double doses
• If you cannot swallow the tablet whole, your doctor may advise other ways to take it, such as crushing and mixing with water or applesauce
• Follow your doctor’s instructions carefully and attend regular follow-up appointments

Storage Information

• Store at room temperature between 20°C to 25°C (68°F to 77°F)
• Keep in the original container, tightly closed, away from moisture and heat
• Keep out of reach of children and pets
• Do not use if the tablets are expired or damaged

Common Side Effects

• Easy bruising or prolonged bleeding from cuts
• Nosebleeds or bleeding gums
• Dizziness or weakness if significant blood loss occurs
• Nausea or upset stomach
• Rare but serious side effects may include severe bleeding, blood in urine or stool, and severe headache (seek medical attention immediately if these occur)