Aptiom

Aptiom (eslicarbazepine acetate) is an anticonvulsant used to treat partial-onset seizures in adults and children aged 4 years and older with epilepsy. It works by stabilising electrical activity in the brain, helping to prevent seizures. Aptiom is typically used as a monotherapy or adjunct therapy, depending on the clinical context.

Benefits

• Helps reduce frequency and severity of partial-onset seizures
• Can be used alone or in combination with other antiepileptic drugs
• Once-daily dosing improves convenience and adherence
• Approved for use in both adults and children (4 years and older)
• Available in tablet form, with a liquid suspension available for paediatric use

Dosage

• Adults (monotherapy or adjunct): Start at 400 mg once daily; may increase to 800–1,200 mg/day
• Children (≥4 years): Dose based on weight; typically 5 mg/kg to 10 mg/kg once daily, up to 1,200 mg/day
• Tablets should be taken once daily, with or without food
• Dose adjustments may be necessary in patients with kidney impairment
• Gradual titration is recommended to reduce the risk of side effects

Warnings and Precautions

• May cause dizziness, drowsiness, or coordination problems—caution when driving or operating machinery
• Risk of serious skin reactions such as Stevens-Johnson syndrome
• May affect sodium levels—monitor for signs of hyponatraemia (e.g., confusion, seizures)
• Use with caution in patients with liver or kidney disease
• May increase the risk of suicidal thoughts or behaviour
• Not recommended during pregnancy unless clearly necessary—may affect foetal development

Usage Instructions

• Take Aptiom exactly as prescribed, once daily
• Can be taken with or without food
• Swallow tablets whole; do not crush or chew
• Do not stop taking suddenly—sudden withdrawal may trigger seizures
• If a dose is missed, take it as soon as possible unless it’s close to the next dose

Storage Information

• Store at room temperature between 15°C and 30°C (59°F and 86°F)
• Protect from moisture and light
• Liquid formulation should not be frozen
• Keep out of reach of children

Common Side Effects

• Dizziness or drowsiness
• Headache
• Nausea or vomiting
• Double vision or blurred vision
• Fatigue or coordination problems
• More serious side effects may include severe skin reactions, low sodium levels, or mood changes