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Cerenia® Injection for Dogs and Cats
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Cerenia Injection is a prescription antiemetic for dogs and cats. It helps prevent and treat acute vomiting in veterinary settings. Available with US shipping from Canada, this page explains uses, safety, and access for those paying without insurance.
What Cerenia Is and How It Works
Cerenia® injectable solution is maropitant, a neurokinin-1 (NK1) receptor antagonist. It blocks the action of substance P, a key neurotransmitter that triggers vomiting at the brain’s vomiting center and in peripheral pathways. By targeting this pathway, the treatment helps control acute vomiting from many causes, including dietary indiscretion, drug effects, and preoperative care. Its use aligns with official labeling for dogs and cats.
Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.
The medicine is typically given by a veterinarian. In some cases, prescribers may instruct trained caregivers to administer doses at home. Follow veterinary directions closely and consult the official label for species-specific guidance.
Who It’s For
This therapy is indicated to prevent and treat acute vomiting in dogs and cats. It is appropriate for many causes of emesis, such as gastrointestinal upset or supportive care around anesthesia as directed by a clinician. Use of Cerenia injection for dogs should follow labeled age restrictions and veterinary oversight.
Pets with known hypersensitivity to maropitant should not receive this medicine. Caution is advised in patients with liver disease, as metabolism occurs primarily in the liver. In very young animals or those with significant underlying conditions, prescribers may choose alternative strategies or adjust monitoring.
For broader context on vomiting and related conditions, see our condition guide on Nausea Vomiting.
Dosage and Usage
Label directions typically involve once-daily dosing for a short course. The injection is commonly administered subcutaneously by a veterinary professional. Where permitted and trained, caregivers may be instructed on safe subcutaneous technique. Doses are calculated by body weight and species. Refer to the official label or your prescriber’s directions for exact schedules and duration.
Maropitant citrate injection is often used for up to several days to stabilize vomiting. Pre-treatment before anesthesia or known triggers may be advised in certain cases. Because dosage regimens vary by species, age, and clinical status, defer to the product insert for precise instructions. Avoid dose changes without veterinary guidance.
Owners can review general pet-med counseling topics in our Pet Medications category.
Strengths and Forms
This medicine is supplied as a sterile multi-dose vial for injection. The commonly published presentation includes Cerenia 10 mg/mL injectable. Vial sizes may vary by market and availability. Packaging may change over time; consult the product label included with your order for the most current details.
Not all sizes are stocked at all times. Supply can differ based on manufacturer lots and distribution.
Missed Dose and Timing
For clinic-administered therapy, timing is managed by the veterinary team. If home administration is prescribed and a dose is missed, a veterinarian may advise giving it when remembered unless the next scheduled dose is near. Do not double up doses. If vomiting persists or worsens, contact the prescriber for guidance.
Storage and Travel Basics
Store your vial as directed on the official label and keep it in the original carton to protect from light. Do not use past the expiration date. Keep out of reach of children and pets. If the prescriber provides syringes for home use, follow their handling and storage instructions for supplies. When traveling, carry the medicine in hand luggage with the prescription label and a copy of veterinary directions.
Do not use the product if the solution appears discolored or contains particulates. Avoid freezing. During transport, maintain reasonable protection from heat and direct sunlight. We use temperature-controlled handling when required during fulfilment.
Pen Handling and Sharps Disposal
This product is supplied in a vial, not a pen. If trained to administer at home, use clean technique with single-use needles and syringes. Dispose of used sharps immediately in an approved sharps container. When the container is full, follow local or state guidance for safe disposal through pharmacies or community programs. Never discard loose needles in household trash or recycling.
Benefits
By blocking NK1 receptors, this therapy helps control acute vomiting and supports rehydration, nutrition, and continuation of oral medications when appropriate. It can reduce distress for pets and make clinic procedures smoother when emesis is a concern. As a dog anti nausea injection, it offers reliable absorption and predictable onset under veterinary supervision. Care teams may use it as part of a broader plan that addresses underlying causes of vomiting.
Side Effects and Safety
- Injection-site discomfort or swelling
- Lethargy or tiredness
- Decreased appetite
- Diarrhea or soft stools
Most effects are mild and temporary. Serious reactions are uncommon but can include allergic responses. Use caution in pets with hepatic impairment. If severe adverse signs occur, such as collapse, hives, or breathing difficulty, seek urgent veterinary care. When used with anesthetics or other centrally acting drugs, monitoring may be increased. Discuss concurrent conditions and medications with the prescriber.
As a general note, maropitant injection for dogs can cause transient discomfort at the injection site; rotating sites and using proper technique may help.
Drug Interactions and Cautions
Maropitant is metabolized in the liver, and interactions are possible with agents that affect hepatic enzymes. Azole antifungals and certain macrolide antibiotics may raise systemic exposure. The prescriber will weigh risks and benefits if these are needed together. Use care with other centrally acting medicines that may compound sedation. This medicine should be used only after the prescriber reviews a full medication list, including supplements and over-the-counter products.
Antibiotics or anti-inflammatories may be used alongside antiemetics when appropriate for the underlying cause. For example, pain control may be indicated after surgery. See Metacam Solution For Injection when analgesia is part of the plan, following veterinary direction.
What to Expect Over Time
Control of vomiting often begins on the day of administration. Many pets require only a short course while the underlying issue is addressed. The prescriber may continue therapy if triggers persist. Consistent follow-up and adherence to directions help support recovery. Keep a simple log of vomiting episodes, appetite, and energy to share at recheck visits. If symptoms worsen or new signs appear, contact the clinic promptly for assessment and possible changes to the plan.
For general care topics that can influence overall stability, our guide on canine diabetes care offers helpful adherence tips that also apply to routine medication routines: Insulin For Dogs.
Compare With Alternatives
Tablets may be chosen for ongoing outpatient control of vomiting or for motion-related indications in dogs. If a prescriber prefers an oral option, consider the tablet formulation here: Cerenia. In other cases, veterinary teams may consider different antiemetic classes such as metoclopramide or ondansetron. Selection depends on the pet’s diagnosis, age, and concurrent therapies.
Pricing and Access
We highlight transparent Canadian pricing with US delivery from Canada. Check availability and Cerenia injection price on this page when logged in. If paying without insurance, compare options and vial sizes to match your prescriber’s directions. You can also review current offers on our Promotions page. For country-of-origin details, see the attribute listing for Canada.
Need more pet-care items in one parcel? Browse our wider Pet Medications selection to consolidate orders when appropriate.
Availability and Substitutions
Stock levels can vary. If a specific vial size is unavailable, a prescriber may recommend an alternative form or schedule, or a different antiemetic from another class. We do not provide restock dates, but the catalog reflects current availability.
Patient Suitability and Cost-Saving Tips
Good candidates include dogs and cats who need short-term control of acute vomiting under veterinary care. Pets with significant liver disease, very young animals, and those on multiple interacting medicines require added caution and monitoring. A complete history helps the prescriber choose the safest plan.
To manage costs, consider multi-month planning if the prescriber anticipates episodic needs. A multi-dose vial can reduce per-dose expense when used for more than one treatment period, as directed. Set simple reminders on a phone or calendar to track doses and clinic rechecks. When ordering, place items together to reduce fulfilment fees when reasonable. If pain or post-op discomfort is also being treated, a coordinated plan that includes analgesia may help; see recovery guidance like Cat Pain Signs for caregiver awareness.
Questions to Ask Your Clinician
- Primary goal: stop vomiting or prevent episodes around procedures?
- Expected course: how many days of therapy are typical?
- Home use: is subcutaneous administration appropriate for this pet?
- Monitoring: what side effects should prompt a call?
- Interactions: any concerns with current medicines or supplements?
- Plan B: if vomiting continues, what is the next step?
Authoritative Sources
Health Canada Drug Product Database
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Can Cerenia Injection be given with food or other oral meds?
Because this therapy is injected, feeding does not affect absorption. Prescribers may combine it with oral medicines when appropriate. The care team often uses it to control vomiting so that oral therapies can be restarted. Provide your veterinarian with a complete list of all medicines and supplements. They will advise on timing and any monitoring needed when multiple therapies are used together for dogs or cats.
How long does a dose of Cerenia Injection typically last?
Label use is commonly once daily, and many pets receive a short course to manage acute vomiting. The exact duration depends on the cause of emesis, species, age, and the broader treatment plan. Some pets improve quickly, while others need several days of support. Follow the dosing schedule provided by your veterinarian and the product insert. Do not change the dose or frequency without professional guidance.
Is Cerenia Injection safe for puppies and kittens?
Veterinary labeling includes age restrictions. The injectable is typically used in dogs eight weeks and older and in cats sixteen weeks and older. Younger animals may have different risk profiles, and dosing decisions rest with the prescriber. If your pet is very young or has underlying conditions, the clinician may suggest an alternative or delay use until appropriate. Always follow the veterinary plan for your pet’s age and health status.
What side effects should I watch for after an injection?
The most common effects are mild and include injection-site pain or swelling, lethargy, and temporary appetite changes. Serious reactions are uncommon but require urgent veterinary care if they occur. If your pet shows hives, trouble breathing, collapse, or persistent vomiting despite treatment, contact the clinic immediately. Keep notes on symptoms to share at follow-up. Your veterinarian will advise if additional monitoring is needed.
Can this medicine be used with anesthesia or pain control?
Yes, veterinary teams often coordinate antiemetics with anesthesia and analgesia when appropriate. The prescriber will select timing and agents to reduce nausea and maintain comfort. Interactions are possible with certain drugs, so a complete medication list is essential. Never add or remove prescription medicines without checking with your veterinarian. If pain is a concern, your clinic may also prescribe an analgesic according to the pet’s needs.
How should I store the vial at home if instructed to administer doses?
Store the vial per the product label and keep it in the original carton to protect from light. Avoid extreme heat and do not freeze. Keep out of reach of children and pets. If you are traveling, carry the medicine with the labeled prescription and veterinary directions. Use clean technique, and discard needles and syringes immediately into a sharps container according to local rules.
What if my pet vomits again soon after treatment?
Record the timing and severity of symptoms and contact the veterinarian. Some pets need additional evaluation if vomiting continues, as underlying causes may require different therapy or diagnostics. Do not repeat doses sooner than directed. The clinician may adjust the plan, suggest further tests, or recommend an alternative antiemetic. Keep your notes concise and bring them to the follow-up appointment for review.
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