Please note: a valid prescription is required for all prescription medication.
Contrave ER is an extended-release weight management tablet for adults with obesity or overweight when used with nutrition and activity changes. You can buy Contrave ER online, view current Canadian pricing, and choose the available strength that matches your clinician’s directions. BorderFreeHealth offers US delivery from Canada for customers paying out of pocket.
The medicine combines naltrexone hydrochloride and bupropion hydrochloride in a sustained-release tablet. The commonly referenced strength is Contrave ER 8/90 mg tablets, containing naltrexone hydrochloride 8 mg and bupropion hydrochloride 90 mg. Availability of pack quantities can vary, so confirm the strength and quantity shown during checkout before completing your order.
Contrave ER Price and Ordering Details
Contrave ER cash price can matter for adults who are managing long-term treatment without insurance coverage. Current product pricing is shown in the ordering area, so you can review the cost before you proceed. If your directions specify Contrave ER 8 mg/90 mg tablets, match the listed strength carefully to the instructions from your clinician.
Canadian pricing may differ from U.S. retail pharmacy costs because pharmacy supply channels, currency, and local pricing rules are different. The final amount can also depend on quantity, current supply, and any shipping-related charges shown at checkout. Do not use coupon wording or discount claims as a substitute for confirming the actual price displayed for your order.
Quick tip: Keep the medicine name, strength, and quantity consistent with your treatment plan when reordering.
What Contrave ER 8/90 mg Is Used For
Contrave ER is used for chronic weight management in certain adults with obesity or overweight. It is intended to be used with a reduced-calorie eating plan and increased physical activity. Treatment decisions depend on body mass index, weight-related conditions, medical history, and how well the medicine is tolerated over time.
The active ingredients work in the brain pathways involved in appetite and reward. Naltrexone is an opioid antagonist, which means it can block opioid effects. Bupropion affects norepinephrine and dopamine signaling and is also used in other medicines for depression and smoking cessation. Together, the combination may help reduce hunger and cravings for some people.
Contrave ER is not a stand-alone weight loss plan. Food choices, movement, sleep, and follow-up monitoring remain important. For broader condition information, the obesity section explains how excess weight can relate to long-term health risks, while the weight management category helps you browse related treatment classes.
How Tablets Are Usually Taken
Follow the directions given by your clinician and the official label. Contrave ER tablets are swallowed whole. Do not cut, crush, or chew them, because altering an extended-release tablet can change how the medicine is released in the body.
Label directions use gradual dose titration over several weeks before the maintenance schedule. This step-up approach is used to improve tolerability, especially during the early treatment period. Avoid taking the medicine with a high-fat meal because this can increase drug exposure and may raise seizure risk.
If a dose is missed, the label advises skipping the missed dose and taking the next dose at the usual time. Do not take extra tablets to make up for a missed dose. If missed doses happen often, ask your clinician how to keep your schedule realistic and safe.
Who Should Not Use This Medicine
Contrave ER is not appropriate for everyone. It should not be used by people with seizure disorder, uncontrolled high blood pressure, bulimia or anorexia nervosa, chronic opioid use, or acute opioid withdrawal. It should also be avoided during abrupt withdrawal from alcohol, benzodiazepines, barbiturates, or antiepileptic drugs unless a clinician has cleared the situation.
The medicine is not recommended during pregnancy. Weight loss during pregnancy can harm the fetus, even when the pregnant person has a higher body weight. People who may become pregnant should discuss planning, monitoring, and what to do if pregnancy occurs while taking therapy.
Tell your clinician about psychiatric history, glaucoma risk, liver disease, kidney disease, blood pressure problems, diabetes medicines, and past head injury or seizure risk factors. These details help determine whether Contrave ER is a reasonable choice or whether another treatment in the weight management articles section may be better to discuss.
Side Effects, Warnings, and Monitoring
Common side effects include nausea, constipation, headache, vomiting, dizziness, dry mouth, diarrhea, abdominal pain, and insomnia. Nausea is often most noticeable early in treatment or during dose increases. Taking tablets exactly as directed and avoiding high-fat meals can reduce some avoidable risks, but side effects should still be discussed if they persist.
Serious risks can include seizures, increased blood pressure or heart rate, liver injury, severe allergic reactions, and angle-closure glaucoma. Bupropion-containing medicines carry a boxed warning about suicidal thoughts and behaviors in children, adolescents, and young adults when used as antidepressants. Any new or worsening mood changes, agitation, unusual behavior, or suicidal thoughts need urgent medical attention.
Monitoring usually includes weight, blood pressure, pulse, tolerability, and medication interactions. People using insulin or sulfonylureas may need extra attention because weight loss and lower food intake can increase hypoglycemia risk. Seek urgent care for seizure symptoms, severe confusion, chest pain, severe allergic swelling, sudden vision changes, yellowing of the skin or eyes, dark urine, or intense abdominal pain.
Drug Interactions and Opioid-Related Cautions
Naltrexone can block the effects of opioid medicines. This matters for pain treatment, cough products containing opioids, opioid use disorder therapy, and emergency care. People who have recently used opioids may need an opioid-free interval before starting naltrexone-containing therapy to avoid withdrawal.
Do not combine Contrave ER with other bupropion-containing medicines unless a clinician specifically determines it is appropriate. Extra bupropion exposure can increase seizure risk. Monoamine oxidase inhibitors require a washout interval, and medicines that lower seizure threshold need careful review.
Alcohol can increase some risks, especially if intake changes suddenly. Tell your clinician about antidepressants, antipsychotics, stimulants, diabetes medicines, seizure medicines, sedatives, over-the-counter products, and supplements. A complete medication list helps prevent unsafe combinations before you place a refill order.
How Quickly Weight Changes May Occur
Some people notice appetite or craving changes during the first weeks, while weight changes usually require more time. The label emphasizes reassessment after an adequate trial at the maintenance dose. If weight loss is limited, clinicians may decide that continuing the medicine is not the best plan.
Individual response varies. Starting weight, calorie intake, activity level, sleep, other medicines, medical conditions, and side effects can all influence results. Avoid comparing your timeline with online reviews because those stories rarely include the full medical context.
Set practical follow-up points with your clinician before starting. Discuss what weight, blood pressure, side effects, mood changes, and daily routine factors should be tracked. This makes it easier to decide whether Contrave ER remains appropriate over time.
Contrave ER Compared With Other Weight Management Options
Contrave ER is an oral tablet that works through naltrexone and bupropion pathways. GLP-1 receptor agonists are incretin-based medicines that work differently and are often given by injection. Because the mechanisms, side effects, restrictions, and expected response patterns differ, one medicine should not be described as universally stronger or better than another.
Ozempic is a semaglutide product used for type 2 diabetes, while certain semaglutide and tirzepatide products are used for chronic weight management under their own labels. Your clinician can explain whether an oral appetite-and-craving medicine, a GLP-1 option, or a non-systemic medicine is more suitable for your history. Related regulated products may include Wegovy and Xenical Orlistat when clinically appropriate.
Contrave ER may appeal to people who prefer tablets over injections, but that preference does not override safety issues. Seizure risk, blood pressure, opioid use, psychiatric history, pregnancy, and drug interactions are central decision points. If those concerns apply, ask about alternative treatments rather than trying to work around a contraindication.
Storage, Travel, and Handling
Store Contrave ER tablets at room temperature in the original container with the cap tightly closed. Keep them away from excess moisture, heat, direct light, children, and pets. Do not transfer tablets into unmarked containers, especially if you take more than one daily medicine.
For travel, keep the pharmacy label with the medicine and carry it in hand luggage. Bring enough medication for the planned trip and allow time for ordering before you run low. BorderFreeHealth uses prompt, express shipping, but personal travel plans should still account for processing, address accuracy, and the need to avoid treatment gaps.
This product is a tablet, not an injectable pen or vial. Pen priming, needles, and sharps disposal do not apply. If you are comparing tablet therapy with injectable weight-management medicines, storage requirements may differ and should be reviewed before switching.
Country of Origin and Canadian Supply Context
Contrave ER supplied through Canadian pharmacy channels may be priced and packaged differently from products sold through U.S. retail pharmacies. The active-ingredient concept remains naltrexone hydrochloride with bupropion hydrochloride in an extended-release tablet, but market names, labeling, and supply presentation can vary by country.
If you specifically want products sourced from Canada, browse the Canada origin section for related items. Always rely on the medicine name, active ingredients, strength, and clinician directions rather than assuming that packaging from different markets will look the same.
Questions to Ask Before Starting or Refilling
- Is my blood pressure controlled enough for this medicine?
- Do any of my medicines contain bupropion or lower seizure threshold?
- Have I used any opioid medicine recently?
- What side effects should prompt a same-day call?
- How should weight, pulse, mood, and sleep be monitored?
- When should we reassess whether treatment is working?
- Which strength and quantity should I choose for my next fill?
These questions are especially important if you pay out of pocket and want to avoid ordering a medicine that may not fit your current plan. Clarifying safety and continuation criteria first can reduce waste and help you use the displayed price information more confidently.
Authoritative Sources
Official prescribing information
This content is for informational purposes only and is not a substitute for professional medical advice.
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What is Contrave ER 8/90 mg used for?
Contrave ER 8/90 mg is used for chronic weight management in certain adults with obesity or overweight. It is taken with a reduced-calorie diet and increased physical activity, and suitability depends on medical history and clinician assessment.
What is the downside of Contrave ER?
Common downsides include nausea, constipation, headache, dry mouth, dizziness, vomiting, and insomnia. More serious concerns include seizure risk, increased blood pressure or heart rate, liver problems, glaucoma, mood changes, and opioid-related interactions.
Is Contrave as effective as Ozempic?
They are different medicines with different uses, mechanisms, and safety profiles. Contrave ER combines naltrexone and bupropion in an oral tablet, while Ozempic is semaglutide and is used for type 2 diabetes. A clinician can compare options based on your goals and health history.
How quickly do you lose weight on Contrave ER?
Response varies. Some people notice appetite or craving changes in the first weeks, but meaningful weight assessment usually requires time at the maintenance dose along with diet and activity changes. Clinicians reassess progress and tolerability during follow-up.
Can Contrave ER be taken with opioids?
Contrave ER contains naltrexone, which can block opioid effects and may trigger withdrawal in people using opioids. Tell your clinician about any opioid pain medicine, cough medicine, or opioid use disorder treatment before starting or refilling.
How should Contrave ER tablets be stored?
Store the tablets at room temperature in the original container, away from excess moisture, heat, direct light, children, and pets. Keep the label with the medicine during travel and do not move tablets into an unmarked container.
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