Sprycel® Tablets for Chronic Myeloid Leukemia

Dasatinib is a prescription tyrosine kinase inhibitor used for certain Philadelphia chromosome–positive leukemias. This page explains how it works, who it’s for, and how to access it with US delivery from Canada. If you pay cash, you can review Dasatinib price without insurance and practical ways to lower expenses.

What Sprycel Is and How It Works

Sprycel® contains dasatinib, a BCR-ABL1 tyrosine kinase inhibitor. It also inhibits Src family kinases. By blocking these signals, the treatment can slow or stop cancer cell growth in chronic myeloid leukemia and some cases of Philadelphia chromosome–positive acute lymphoblastic leukemia. Effects depend on diagnosis, prior therapies, and adherence.

Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

Mechanistically, this medicine binds to the ATP-binding site of BCR-ABL1, reducing downstream signaling that drives uncontrolled cell division. It may help achieve hematologic and cytogenetic responses. Your clinician will monitor blood counts and organ function, and may adjust your plan per the approved label.

Learn more about its science in our overview: Exploring Dasatinib Mechanism Of. For condition context, see Chronic Myeloid Leukemia.

Who It’s For

This medicine is approved for adults with Philadelphia chromosome–positive chronic myeloid leukemia in chronic, accelerated, or blast phase. It is also used for adults with Philadelphia chromosome–positive acute lymphoblastic leukemia. Pediatric use exists under labeled conditions; the care team will follow weight-based and safety guidance from the official labeling.

People with significant liver issues, a history of pulmonary arterial hypertension, or uncontrolled cardiac problems may not be candidates. Those with low baseline blood counts require close monitoring. Discuss past bleeding events, recent procedures, and all medicines, vitamins, and herbs with your healthcare professional.

For ALL-specific education, see Philadelphia Chromosome Positive Acute.

Dosage and Usage

Follow your prescriber’s instructions and the official package insert. The treatment is generally taken once daily, with or without food. Swallow tablets whole with water. Do not split, crush, or chew. Caregivers should avoid direct contact with broken tablets.

Some patients may receive Dasatinib 70mg tablets based on diagnosis and clinical factors. Your schedule, laboratory checks, and any changes come from the labeled recommendations. Avoid grapefruit and grapefruit juice. If you use antacids, take them at a different time as directed on the label.

Proton pump inhibitors and H2 blockers can reduce the medicine’s absorption. If you need acid-reducing therapy, your clinician will refer to the label for appropriate timing or alternatives. Alcohol intake should be discussed with your clinician, especially if you have liver concerns.

Strengths and Forms

Film-coated tablets are commonly available in multiple strengths. Availability can vary by supplier and country. Your prescription will specify the tablet strength and quantity authorized.

• Dasatinib 100mg tablets
• Additional marketed strengths include 20 mg, 50 mg, 70 mg, 80 mg, and 140 mg tablets

Package sizes and supplier stock may differ. The dispensing pharmacy follows your prescriber’s directions.

Missed Dose and Timing

If you miss a dose, take it as soon as you remember on the same day. If it is almost time for the next dose, skip the missed dose. Do not take two doses at once. Keep a consistent daily schedule and use reminders so you do not miss doses. When uncertain, follow the guidance in the official label and consult your prescriber’s office.

Storage and Travel Basics

Store tablets at room temperature in the original container, closed tightly, and protected from moisture. Keep away from children and pets. Do not store in a bathroom. If any tablets are damaged, avoid handling powder and follow safe-disposal instructions.

For travel, keep the medicine in your carry-on with the pharmacy label matching your ID. Bring a copy of the prescription and a medication list. Check security rules before flying. Do not transfer tablets into unmarked organizers when crossing borders. If your itinerary changes time zones, maintain your once-daily rhythm within a similar 24-hour window.

Benefits

This therapy targets a known driver of certain leukemias. Many patients appreciate once-daily oral dosing and the ability to take it with or without food. Your care team can track response with blood tests and imaging when indicated. Adherence and regular monitoring help support long-term control per labeled outcomes.

Side Effects and Safety

• Low blood counts: anemia, neutropenia, thrombocytopenia
• Headache or fatigue
• Nausea, vomiting, or diarrhea
• Skin rash or itching
• Muscle or joint pain
• Fluid retention, including swelling

Serious risks can include pleural effusion, pulmonary arterial hypertension, severe bleeding, infections, QT prolongation, and liver problems. Report chest pain, shortness of breath, rapid weight gain, severe dizziness, fainting, yellowing of the skin or eyes, or unusual bleeding or bruising. Your clinician will order regular blood work and may pause or adjust therapy in line with the label if safety issues arise.

For additional context, review our guide: Understanding Tasigna Side Effects as a class-related perspective.

Drug Interactions and Cautions

Strong CYP3A4 inhibitors (such as certain azole antifungals or macrolide antibiotics) can raise dasatinib levels and increase side effects. Strong CYP3A4 inducers (such as rifampin or St. John’s wort) can lower levels and reduce effectiveness. Always share your medication list with your healthcare professional.

Acid-reducing agents can decrease absorption. Avoid proton pump inhibitors and H2 blockers unless your clinician provides label-guided timing or alternatives. Separate antacids as directed to reduce interaction risk. Use caution with anticoagulants or antiplatelet agents due to bleeding risk.

To learn about a related TKI, see How Bosulif Treats Cml. This is for education only; decisions should follow your own label and clinician advice.

What to Expect Over Time

Your team will track early blood count changes, then assess deeper responses on a schedule consistent with labeling. Some effects, such as fatigue or mild fluid retention, may appear earlier and often improve with supportive care. Pleural symptoms should be reported promptly. Consistent daily dosing and keeping all lab appointments support your care plan.

If therapy changes are needed, your prescriber will follow labeled algorithms. Do not stop the medicine without medical guidance. Keep a diary of symptoms, doses, and questions to bring to each visit.

Compare With Alternatives

Other approved options for similar indications include imatinib and bosutinib. Your clinician may also consider nilotinib or asciminib in specific scenarios. Choice depends on phase of disease, prior response, comorbidities, and potential interactions.

Compare options here: Gleevec and Bosulif. These links are informational and not treatment advice. Decisions rely on your diagnosis and the official labels.

Pricing and Access

We list current availability and Canadian pricing with clear options for US delivery from Canada. You can check Dasatinib price on the product page and see how dispensing works with a valid prescription. Some patients look at Dasatinib cost per pill to plan monthly budgets. Your out-of-pocket will depend on dose, quantity, and pharmacy source.

You can browse promotions when available at Promotions. Our checkout uses encrypted payment processing to protect your information. For country details, see Canada.

Availability and Substitutions

Supply can vary by strength and manufacturer. If a selected option is on backorder, your prescriber may recommend an approved alternative or a different pack size. Brand and generic products follow their respective labels and local regulations. If you prefer a specific manufacturer, include that note with your prescription when you upload.

When inventory allows, you may choose to Buy dasatinib tablets with your prescriber’s authorization. If an item is unavailable, your clinician may suggest another TKI that fits your medical history.

Patient Suitability and Cost-Saving Tips

This therapy may suit adults with Philadelphia chromosome–positive disease who can adhere to daily dosing and clinic monitoring. It may not suit those with persistent severe cytopenias, uncontrolled cardiac or pulmonary conditions, or significant drug interactions. Your care team will weigh benefits and risks.

To manage costs, ask about multi-month fills when appropriate, which can reduce per-fill fees. Set refill reminders so you do not miss doses. Discuss Generic dasatinib price with your clinician if brand alternatives are considered. If you use a copay card or financial assistance program, follow the program’s requirements and your prescriber’s guidance.

Questions to Ask Your Clinician

• Monitoring plan: which labs and how often
• Safety signs: when to call for urgent symptoms
• Food and beverages: grapefruit or alcohol limits
• Interaction checks: acid reducers and supplements
• Travel steps: time zones and documentation
• Contingency plan: handling missed or held doses

Authoritative Sources

Manufacturer Prescribing Information (Bristol Myers Squibb)

FDA DailyMed: Dasatinib

Health Canada Drug Product Database

Ready to proceed? Upload your prescription, choose your quantity, and checkout for prompt, express shipping with US delivery from Canada. This information is educational and not a substitute for care from your healthcare professional.