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Diacomit® Capsules and Powder for Dravet Syndrome
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Diacomit® is a prescription antiseizure medicine used with clobazam to help manage seizures in Dravet syndrome. This page outlines what it treats, how to take it, important safety points, and how you can request supply with US shipping from Canada. You can also review practical details if paying without insurance.
What Diacomit Is and How It Works
Diacomit contains stiripentol, an adjunctive therapy for seizures linked to Dravet syndrome. It works by affecting gamma-aminobutyric acid (GABA) pathways and by interacting with liver enzymes that process other medicines, including clobazam. The result can be added seizure control when used in a prescribed combination. Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.
This treatment is taken by mouth with food. Capsules are swallowed whole. The powder is mixed with water and consumed right away. For condition information and community resources, see our page on Dravet Syndrome. If you are browsing related products, explore our Neurology category and learn about items sourced from Canada.
The powder presentation is manufactured by Biocodex. If a liquid-style option is needed, Biocodex powder for oral suspension offers a practical alternative to capsules in patients who cannot swallow solid forms.
Who It’s For
This medicine is approved as add-on therapy to clobazam for patients with Dravet syndrome. It is generally used in children and adults when a prescriber believes additional control is needed. People with a known allergy to stiripentol or formulation components should not take it. Those with significant liver problems, current low white blood cells or platelets, or severe malnutrition may require extra caution and closer monitoring.
The powder form may be suitable for those unable to swallow capsules. Typical Biocodex powder for oral suspension uses include pediatric patients who need flexible administration. Use only under guidance of a healthcare professional and in line with the approved label.
Dosage and Usage
Your prescriber sets the dose based on weight, current antiseizure medicines, and response. Doses are usually split into two or three daily administrations with meals. Swallow capsules whole; do not crush or open them. If you cannot swallow capsules, your clinician may choose the powder for oral suspension. Mix the powder with water only when ready to take, and drink it promptly.
Take each dose at consistent times. Avoid alcohol. Check food and juice restrictions; many patients are advised to avoid grapefruit products. This therapy can raise levels of other medicines such as clobazam. Your healthcare professional may monitor for sleepiness or reduced appetite when starting or adjusting therapy.
For those looking at capsule sizes, Stiripentol 250 mg capsules may be used when smaller increments are needed. Dosing should follow the official prescribing information and your clinician’s instructions.
Strengths and Forms
Available forms include capsules and a powder that is mixed into a suspension immediately before use. Common strengths include 250 mg and 500 mg. Availability may vary by market and by time.
The powder format can help patients who prefer a measured mixture instead of swallowing a capsule. For reference to the manufacturer format, see Biocodex powder for oral suspension in the sections above.
Missed Dose and Timing
If you miss a dose, take it when you remember unless it is close to the next scheduled time. If it is almost time for the next dose, skip the missed dose and return to the regular schedule. Do not double doses. Consistency matters for seizure control, so set reminders or use a dosing log to support routine use.
Storage and Travel Basics
Store in the original packaging at room temperature and keep it dry. Protect from moisture and excessive heat. Keep out of reach of children and pets. Do not prepare the powder in advance; mix right before taking and consume promptly. When traveling, carry your prescription label and a medication list. Keep a spare day’s supply in a separate bag in case of delays. Our partners use temperature-controlled handling when required.
Benefits
As an add-on therapy, this medicine may help reduce seizure frequency or severity when combined with clobazam as directed. The availability of both capsules and a mixable powder provides flexibility. Taking it with food may improve tolerance. Because it can influence how the body processes other antiseizure agents, prescribers often monitor closely and adjust companion therapies if needed.
Side Effects and Safety
- Sleepiness or sedation
- Decreased appetite
- Weight loss
- Insomnia or agitation
- Ataxia or unsteady movements
- Nausea or vomiting
- Irritability
Serious risks can include low white blood cells, low platelets, and increased liver enzymes. Your clinician may order periodic blood counts and liver tests. Mood changes, including suicidal thoughts, have been reported with antiseizure treatments. Seek urgent help for severe rash, persistent vomiting, jaundice, unusual bleeding, or behavior changes. If combined with insulin or sulfonylureas, monitor carefully for hypoglycemia as directed by your clinician.
Drug Interactions and Cautions
This treatment inhibits certain liver enzymes (including CYP2C19 and CYP3A4) and may increase levels of other drugs. Sedation can deepen when combined with benzodiazepines, opioids, or alcohol. Your prescriber may avoid or monitor narrow-therapeutic-index substrates of these enzymes. Clobazam and valproate commonly require attention when used together with stiripentol. Avoid grapefruit products unless your clinician advises otherwise. Always provide a complete medication list, including supplements and over-the-counter products.
For broader context on neurological therapies and safety, you may find these educational articles useful: Topamax Uses, Zoloft Side Effects, and Aricept Facts.
What to Expect Over Time
Response varies. Some patients may notice steadier seizure control after a period of consistent dosing with their full regimen. Your healthcare professional may track appetite, weight, sleepiness, and lab results over time. Keep a seizure diary to report changes at follow-up visits. Do not stop or change dosing without discussing it with your prescriber, as abrupt changes can trigger seizures.
Compare With Alternatives
Other antiseizure options may be considered based on seizure type and history. Two medicines sometimes discussed with specialists include Banzel (rufinamide), often used for Lennox–Gastaut syndrome, and Aptiom (eslicarbazepine), used for focal-onset seizures. These options are not direct substitutes for every patient or condition. Your clinician will determine suitability.
Pricing and Access
We offer Canadian pharmacy pricing with transparent options for self-pay. If you are comparing offers, search terms like Diacomit price without insurance can help you evaluate typical out-of-pocket scenarios alongside your clinician’s plan. You can also Buy stiripentol through our request process once your prescriber has sent a valid script. We provide fulfilment that Ships from Canada to US. For occasional savings opportunities, see our Promotions page. Checkout uses encrypted processing.
To browse related areas, visit Neurology or read more about the condition at Dravet Syndrome.
Availability and Substitutions
Stock and packaging may vary by strength and form. If a specific presentation is temporarily unavailable, your prescriber may recommend an alternative form or a different adjunct therapy. You can Order Diacomit online by starting a request; our team will coordinate prescription verification with your clinician.
Patient Suitability and Cost-Saving Tips
This therapy may suit patients who need add-on control with clobazam and can follow regular dosing with meals. It may not be suitable for those with significant liver disease, active blood count problems, or known hypersensitivity to stiripentol. Share your full medication list and medical history so your prescriber can evaluate interactions and monitoring needs.
For budgeting, ask about multi-month fills to reduce per-fill handling fees. Set calendar reminders for refills to prevent lapses. When traveling, carry extra doses in hand luggage and keep your prescription label accessible for security checks. If your costs change, ask your clinician about dose packaging or schedule adjustments that still follow the label while supporting adherence.
Questions to Ask Your Clinician
- Is this add-on therapy appropriate for my seizure pattern?
- How will this interact with clobazam or valproate?
- What side effects should I watch for in the first weeks?
- How often will blood tests or weight checks be needed?
- What should I do if appetite declines or sedation increases?
- Could the powder form be better than capsules for me?
Authoritative Sources
Biocodex (Manufacturer)FDA DailyMed Prescribing InformationHealth Canada Drug Product Database
Start your request at Borderfreehealth for prompt, express shipping and US delivery from Canada. This information is not a substitute for professional medical advice. Always follow your prescriber’s guidance and the official label.
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How is Diacomit taken with clobazam?
This medicine is prescribed as an add-on to clobazam. Your clinician sets the dose by weight, splits it into multiple daily doses, and advises taking it with food. Capsules should be swallowed whole. The powder is mixed with water and taken right away. Your prescriber may monitor for sleepiness and appetite changes and check labs. Never change your other seizure medicines without discussing it with your healthcare professional.
What are common side effects of stiripentol?
Common effects include sleepiness, decreased appetite, weight loss, nausea, vomiting, agitation, and unsteady movements. Some patients experience insomnia or irritability. Serious risks include low white blood cells, low platelets, and increased liver enzymes. Your clinician may order blood tests. Report severe rash, persistent vomiting, jaundice, or behavior changes promptly. Seek urgent help for signs of allergic reaction such as swelling or breathing problems.
Can I open the capsules or prepare the powder ahead of time?
Capsules should be swallowed whole and not opened or crushed. If you cannot swallow capsules, your prescriber may choose the powder for oral suspension. Mix the sachet with water only when ready to take and consume the mixture promptly. Do not store the mixture for later use. Follow the instructions provided with your prescription and ask your pharmacist if you have questions about the mixing steps.
Are there food or drink interactions to avoid?
Take doses with food. Many patients are advised to avoid grapefruit products because they can affect liver enzymes that process medicines. Alcohol can increase sedation and is usually avoided. Because this therapy interacts with other antiseizure medicines, your prescriber may adjust them. Provide a full list of medicines and supplements at each visit so your clinician can check for interactions and monitor you closely.
Who should not use this treatment?
People with a known allergy to stiripentol or the formulation should not take it. Those with severe liver disease, low white blood cells, or low platelets may need special monitoring or an alternative plan. Use only under the guidance of a healthcare professional, typically as add-on therapy to clobazam for Dravet syndrome. Discuss your medical history and all current medicines with your prescriber before starting.
How should I store the capsules and powder?
Keep the medicine in its original packaging at room temperature. Protect it from moisture and excessive heat, and keep it out of reach of children. Mix the powder with water only when ready to take and drink the mixture right away. When traveling, carry it in your hand luggage with the prescription label. Consider packing a small buffer supply in a separate bag in case of delays.
What if the pharmacy cannot supply my usual pack?
Availability can vary by strength and form. If your usual presentation is temporarily unavailable, your prescriber may recommend a different pack size or form based on your dosing needs. We can coordinate with your clinician to verify any substituted presentation before dispensing. Start your request early to allow time for prescription verification and to discuss options with your healthcare professional.
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