Please note: a valid prescription is required for all prescription medication.
Diltiazem XC® Extended-Release Capsules for Hypertension
Buy more, save more: Get 20% off when you buy 3 or more of any one product. Use code LESS20 at checkout.
Coupon code cannot be combined with other offers. Sale applies to all products originating from Canada. Maximum allowable quantity equal to a 90 day supply per single order.
Price range: $166.99 through $210.99
Secure Encrypted Payments
Diltiazem XC is an extended-release calcium channel blocker used for high blood pressure and chronic stable angina. It helps relax blood vessels and may reduce heart rate, lowering the heart’s workload. This page explains how the medicine works, who it’s for, and how to use it safely. It also outlines ways to manage costs if you pay without insurance.
What Diltiazem XC Is and How It Works
Diltiazem XC® contains diltiazem hydrochloride in a controlled-release capsule. As a non-dihydropyridine calcium channel blocker, it limits calcium entry into cardiac and vascular smooth muscle. This action helps lower blood pressure and can ease angina by reducing oxygen demand and improving blood flow. Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.
This class can slow heart rate and decrease the force of contraction. It may be used as part of a broader cardiovascular plan guided by your clinician. Do not use it for sudden chest pain relief.
Who It’s For
This treatment is used for adults with hypertension and for chronic stable angina per approved labeling. It is not for immediate relief of acute chest pain. People with certain rhythm disorders, very low blood pressure, or advanced heart block without a pacemaker should avoid it. Those with heart failure, liver problems, or kidney concerns should discuss risks and monitoring with a healthcare professional.
Some patients with atrial fibrillation may be managed with rate-control therapies. Decisions vary, and your prescriber will determine whether this medicine fits your plan. Learn more about related conditions like Hypertension, Angina, and Atrial Fibrillation.
Dosage and Usage
Extended-release capsules are typically taken once daily, as directed. An example regimen is Diltiazem XC once daily, taken at the same time each day. Swallow capsules whole. Do not chew, split, or crush. You may take it with or without food, but be consistent day to day.
Keep a log of your home blood pressure readings. Share results with your prescriber during follow-up visits. If you also take other heart medicines, your clinician may adjust your treatment plan to limit additive effects.
Strengths and Forms
The product is generally available as extended-release capsules in multiple strengths. Availability may vary.
- Diltiazem XC 120 mg capsules are a common starting option
- Other strengths often include 180 mg, 240 mg, 300 mg, and 360 mg
- Packaging sizes may vary by partner pharmacy
Capsules are designed for controlled release over 24 hours. Do not substitute strengths without prescriber guidance.
Missed Dose and Timing
If you miss a dose, take it when you remember unless it is close to your next dose. If it is near the next scheduled time, skip the missed dose and resume your regular schedule. Do not double up. Consistent daily timing helps maintain steady levels.
Storage and Travel Basics
Store capsules at room temperature in a dry place away from direct light. Keep them in the original, child-resistant container with the prescription label. For travel, bring enough supply, plus a copy of your prescription. Keep medicines in your carry-on when flying and follow security rules. If you cross time zones, keep your usual interval in local time.
Use a weekly organizer only if you can keep it closed and away from moisture. Dispose of outdated capsules according to local guidance. Ask a pharmacist about take-back programs if available.
Pen Handling and Sharps Disposal
No pens or needles are involved. These are oral capsules, so sharps disposal does not apply.
Benefits
This therapy can help lower blood pressure and reduce angina episodes when used as directed. Once-daily dosing supports adherence. Multiple strengths allow your prescriber to tailor your plan. It can be combined with other agents if needed, following professional guidance. For a broader view of options, see our Cardiovascular category.
Side Effects and Safety
- Headache or dizziness, especially when starting
- Fatigue or weakness, sometimes with slow pulse
- Flushing or warmth in the face
- Peripheral edema, especially in the ankles
- Nausea or stomach discomfort
Serious effects are uncommon but may include very low blood pressure, worsening heart failure, heart block, liver problems, or severe rash. Seek medical attention for fainting, marked shortness of breath, yellowing skin or eyes, or swelling that rapidly worsens. Avoid abrupt discontinuation unless your prescriber advises otherwise.
Drug Interactions and Cautions
Diltiazem is a CYP3A4 substrate and inhibitor. Strong CYP3A4 inhibitors or inducers can change its levels. Certain statins, especially simvastatin and lovastatin, may require caution. Additive effects can occur with beta-blockers or other rate-slowing agents. Digoxin levels may rise. Avoid grapefruit and grapefruit juice unless your clinician says otherwise. Review all medicines, vitamins, and herbs with your prescriber. For related class context, see Verapamil Uses.
What to Expect Over Time
Blood pressure often improves gradually with steady use. Angina prevention benefits may build with consistent daily dosing. Your prescriber may adjust the strength after reviewing your response and any side effects. Keep regular follow-up to review vitals, symptoms, and medication lists. Do not stop suddenly; discuss any changes before you make them.
Compare With Alternatives
Other approved calcium channel blockers can be considered if this option does not fit your plan. Brand nifedipine formulations such as Adalat® Xl are long-acting dihydropyridines focused on vessel relaxation. Generic nifedipine options like Nifedipine Xr offer once-daily profiles too. Your prescriber will choose based on your clinical picture and other medicines.
Pricing and Access
We list transparent options so you can compare the Diltiazem XC price with Canadian supply. Many patients paying out of pocket use Canadian pricing to stretch budgets. If you order through our site, you can order Diltiazem XC online with a valid prescription. We provide US shipping from Canada. Check the Country Of Origin attribute on product pages. Secure purchasing is supported with encrypted checkout.
If you take this for heart conditions, discuss budget planning with your prescriber. Some patients coordinate refills to align with clinic visits or lab checks. If you live with angina, you can review symptoms and care basics here: Angina Symptoms.
Availability and Substitutions
Stock can vary across partner pharmacies. If a strength is unavailable, your prescriber may consider a different dose or an alternative in the same class. If needed, your clinician can also discuss Diltiazem XC generic labeling and comparable extended-release options.
Patient Suitability and Cost-Saving Tips
This medicine may fit adults who need once-daily blood pressure or angina control and can follow monitoring advice. It may not suit those with certain rhythm problems, advanced conduction disease without a pacemaker, or very low baseline blood pressure. If you have liver or heart failure, your prescriber may adjust your plan.
- Multi-month fills: reduce pharmacy trips and per-fill fees
- Set reminders: support steady dosing adherence
- Travel buffer: carry extra days for delays
- Home BP logs: enable precise adjustments
- Avoid duplicates: check combinations with other heart drugs
For educational resources on related therapies, see Atenolol Uses and review signs of emergencies at Heart Attack.
Questions to Ask Your Clinician
- My goals: what blood pressure range should I aim for?
- Timing: what time of day best fits my other medicines?
- Interactions: which drugs or foods should I avoid?
- Side effects: what changes should prompt a call?
- Monitoring: how often should I check home readings?
- Angina plan: what is my action plan for chest pain?
- Follow-up: when should we reassess my dose?
Authoritative Sources
| Source | Link |
|---|---|
| FDA DailyMed | DailyMed Search |
| Health Canada DPD | Drug Product Database |
| FDA DailyMed (General) | Diltiazem Listings |
Ready to proceed? You can place your order today with prompt, express shipping. Ships from Canada to US. This information is not a substitute for professional medical advice. Always follow your prescriber’s directions and the official label.
Express Shipping - from $25.00
Shipping with this method takes 3-5 days
Prices:
- Dry-Packed Products $25.00
- Cold-Packed Products $35.00
Shipping Countries:
- United States (all contiguous states**)
- Worldwide (excludes some countries***)
Standard Shipping - $15.00
Shipping with this method takes 5-10 days
Prices:
- Dry-Packed Products $15.00
- Not available for Cold-Packed products
Shipping Countries:
- United States (all contiguous states**)
- Worldwide (excludes some countries***)
Is Diltiazem XC interchangeable with other Diltiazem forms?
Not always. Different formulations release medication at different rates. Only switch forms under medical supervision.
Can Diltiazem XC cause swelling?
Yes, fluid retention and swelling of the ankles or feet can occur. Contact your doctor if swelling becomes severe.
When should I take Diltiazem XC?
It can be taken any time of day but should be taken at the same time every day for best results.
Can Diltiazem XC be used in older adults?
Yes, but older adults may be more sensitive to its effects. Lower starting doses and close monitoring may be needed.
What should I do if I miss a dose of Diltiazem XC?
Take it as soon as you remember, unless it is close to the next dose. Do not double up.
How does extended-release diltiazem differ from immediate-release forms?
Extended-release capsules release medicine slowly over 24 hours, providing steadier effects and once-daily convenience. Immediate-release tablets act over a shorter period and are taken more often. Diltiazem XC is designed to maintain levels through the day, which can reduce peaks and troughs. Your clinician will choose a version based on your condition, other medicines, and how you tolerate therapy.
Can I open or sprinkle the capsules if I have trouble swallowing?
Do not crush, chew, or open extended-release capsules. Altering the capsule can change how the medicine is released and may increase side effects or reduce benefit. If swallowing is difficult, speak with your prescriber or pharmacist. They can review alternative strengths, different formulations, or other therapies that match your needs without compromising controlled release.
What if I have liver or kidney issues?
People with liver impairment may need closer monitoring because diltiazem is extensively metabolized in the liver. Kidney issues are also relevant when assessing overall cardiovascular therapy. Your clinician may adjust your plan and follow labs or vitals more closely. Share all medical conditions, recent test results, and your full medication list before starting or changing Diltiazem XC.
Can I take this with a beta‑blocker or digoxin?
Combining diltiazem with beta‑blockers or digoxin may increase the risk of low heart rate or conduction problems. It can also raise digoxin levels. Some patients use such combinations under close supervision, but others should avoid them. Your prescriber will decide based on your rhythm, blood pressure, and overall risk profile. Report dizziness, fainting, or new fatigue promptly.
Will grapefruit or certain antibiotics affect this medicine?
Grapefruit can increase diltiazem levels by affecting CYP3A4. Some antibiotics and antifungals, as well as other CYP3A4 inhibitors or inducers, can also change exposure. Always review new prescriptions and supplements with your clinician or pharmacist. If a potential interaction is identified, they may suggest an alternative or adjust the plan and monitoring to maintain safety.
How quickly will I notice changes in blood pressure or chest discomfort?
Responses vary. Many people see gradual blood pressure improvement with steady daily use. Angina prevention can also build with regular dosing. Your clinician may reassess after an initial period and adjust the strength if needed. Keep taking the medicine as directed, track home readings, and note any chest discomfort trends to discuss at follow-up appointments.
Do I need a prescription, and can I switch strengths later?
Yes, a valid prescription is required and verified before dispensing. Switching strengths should only happen under prescriber guidance, based on your response and side effects. Do not change doses on your own. If pill size or tolerability is a concern, talk to your clinician about adjustments or alternatives that still meet your treatment goals.
Rewards Program
Earn points on birthdays, product orders, reviews, friend referrals, and more! Enjoy your medication at unparalleled discounts while reaping rewards for every step you take with us.
You can read more about rewards here.
POINT VALUE
How to earn points
- 1Create an account and start earning.
- 2Earn points every time you shop or perform certain actions.
- 3Redeem points for exclusive discounts.
How to book an appointment
- 1Create Begin by completing a profile or log into your existing account. This step ensures we have the necessary information to provide you with a service that's tailored to your needs. account and start earning.
- 2Scheduling an appointment with our online booking system is easy. Pick a day and time that suits you. You’ll receive an immediate confirmation, without the wait.
- 3Discuss your concerns and symptoms and receive a thorough diagnosis from one of our licensed doctors during a confidential video appointment.
- 4If you've been prescribed medication, your Rx is sent directly to one of our licensed pharmacies and delivered right to your door.
Get Started
To book an online doctor appointment, register for an account or login. After doing so, you can book your visit on this page.
