Dovato® Tablets for HIV-1

This medicine is a complete HIV-1 regimen in a single daily tablet. You can access Canadian pricing with US delivery from Canada. Many patients search for Dovato® without insurance; this page explains access, use, and safety details so you can plan your next steps.

What Dovato Is and How It Works

Dovato combines dolutegravir, an integrase strand transfer inhibitor, with lamivudine, a nucleoside reverse transcriptase inhibitor. Together, they block HIV replication at two steps in the viral life cycle. It is a complete regimen for treatment of HIV-1 in adults and adolescents who meet label criteria. Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

This fixed-dose option may be used in people with no known resistance to either component and who do not have hepatitis B coinfection. If you have chronic hepatitis B, your clinician may recommend adding a separate HBV-active agent, since lamivudine alone is not sufficient for HBV. Speak with your healthcare professional about your medical history, current medicines, and goals before starting therapy.

Labeling describes dolutegravir lamivudine 50/300 mg tablets as once-daily. After taking a dose, the integrase inhibitor component helps prevent viral DNA from integrating into human DNA, and the nucleoside component reduces the virus’s ability to copy itself. Consistent daily use is important to help maintain viral suppression and reduce the risk of resistance over time.

Learn more about HIV care and testing through our resources on Hiv and Antivirals. For background on treatment options, see Biktarvy HIV and Aptivus For HIV.

Who It’s For

This treatment is indicated as a complete regimen for adults and adolescents weighing at least 40 kg with HIV-1 and no known resistance to dolutegravir or lamivudine. It is generally considered for people starting therapy or those switching from a stable regimen when appropriate.

It is not recommended for patients with hepatitis B coinfection unless an additional HBV-active agent is used. The fixed-dose tablet is also not recommended in significant renal impairment where lamivudine dose adjustments are required. Discuss pregnancy, plans to conceive, and breastfeeding with your clinician. People with a history of hypersensitivity to either component should avoid this medicine.

Dosage and Usage

The standard schedule is one tablet taken once daily as directed on the official label. You may take it with or without food. Swallow the tablet whole with water; do not crush or split unless your prescriber confirms it is suitable. Consistency matters. Taking your dose at the same time each day can help support adherence.

If you use antacids or supplements containing aluminum, magnesium, calcium, iron, or zinc, separate them from this medicine. Taking the antiviral at least two hours before or six hours after those products may help maintain absorption, as advised in the label. Never start, stop, or change any antiretroviral therapy without consulting your healthcare professional.

Keep a list of all medicines and supplements you use. Share it with your prescriber and pharmacist to check for clinically relevant interactions or contraindications. For added context on testing and monitoring, visit our article on Types Of HIV Tests.

Strengths and Forms

The product is supplied as film-coated tablets containing dolutegravir lamivudine 50/300 mg. Packaging and tablet appearance may vary by manufacturer and market. Availability can differ by pharmacy and timeframe.

Missed Dose and Timing

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the next dose at the regular time. Do not take two doses at once. If you vomit soon after a dose, check with your prescriber for personalized guidance on whether to take another dose. Keep a simple reminder system to help avoid missed doses.

Storage and Travel Basics

Store tablets at standard room temperature in the original container with the desiccant, away from excessive moisture and direct light. Keep the bottle tightly closed and out of reach of children and pets. Do not store in a bathroom. Check the bottle’s lot number and expiration date before each refill cycle.

When traveling, keep your medicine in your carry-on luggage with a copy of your prescription and your prescriber’s contact information. Use a daily pill organizer only if it preserves dryness, and keep a small supply in a separate bag as a backup. Our partners use temperature-controlled handling when required, and you should avoid leaving tablets in cars or other environments subject to heat or freezing conditions.

Pen Handling and Sharps Disposal

This is a tablet, so injection handling and sharps disposal do not apply.

Benefits

This two-drug regimen may simplify therapy to one pill once daily. It can reduce pill burden compared with certain three-drug regimens. The antiviral components act at different steps of the HIV life cycle, which may support durable viral suppression when taken as directed. Many patients value fewer tablets and a consistent routine aligned with daily habits.

Side Effects and Safety

• Headache
• Nausea
• Diarrhea
• Insomnia
• Fatigue
• Dizziness

Serious but less common issues can include hypersensitivity reactions, liver problems, lactic acidosis with severe hepatomegaly, and immune reconstitution syndrome. Worsening of hepatitis B can occur if you have HBV and stop antiviral therapy that has activity against HBV. Weight changes have been reported with some integrase inhibitor-containing regimens. Seek immediate care for signs of allergic reaction such as rash with fever, facial swelling, or difficulty breathing.

Drug Interactions and Cautions

Do not combine with dofetilide. Antacids and mineral supplements that contain polyvalent cations can reduce absorption; separate dosing according to the label. Rifampin and certain enzyme inducers may lower exposure and could require a regimen change. Metformin coadministration may require monitoring and dose considerations. Always review any new medicine, supplement, or herbal product with your healthcare professional.

Alcohol and recreational drugs can complicate adherence and safety. Discuss these factors openly with your clinician. If you have kidney or liver disease, ensure your care team reviews your labs before and during therapy. Visit our overview of prevention and treatment choices in Tenvir EM Tablet and learn more public health context at HIV Testing Day.

What to Expect Over Time

With steady daily use, many patients see their viral load decrease on lab testing as directed by their prescriber. You may not feel different day-to-day, so labs and follow-up visits are important. If you experience side effects, report them promptly; your clinician can advise supportive measures or consider alternatives when appropriate.

Set medication reminders, pair dosing with a routine, and keep an extra few days’ supply with your travel documents. If your healthcare professional orders blood tests, try to keep appointments on schedule to support long-term control. Adherence and open communication with your care team remain central to success.

Compare With Alternatives

Other complete regimens include rilpivirine/dolutegravir as a two-drug option for certain switch scenarios, and triple-drug options with different nucleoside backbones. Two alternatives we offer include Juluca® and Delstrigo®. Your prescriber will match a regimen to your history, resistance profile, coinfections, and preferences.

Pricing and Access

We list transparent information so you can compare options and discuss them with your prescriber. If you are evaluating the Dovato tablets price and considering assistance options, we can guide you to resources and explain how cross-border fulfillment works. Our pharmacy partners provide Canadian pricing with quality checks and Ships from Canada to US fulfilment. For many, understanding the Dovato cash price helps plan around copays or deductibles while reviewing benefit design.

To see current options and deals, visit our Canada section and, if coupons are available, check our Promotions page. For clinical background on broader therapy classes, explore our primer on Biktarvy HIV.

Availability and Substitutions

Supply can vary. If this product is temporarily unavailable, your prescriber may recommend an appropriate alternative that fits your regimen goals. Patients sometimes ask whether they can order Dovato from Canada; we support prescription-based access through licensed partners and will communicate options clearly. We do not promise restock dates, but we will update listings as inventory changes.

Patient Suitability and Cost-Saving Tips

This two-drug regimen may suit adults who meet label criteria, have no known resistance to either component, and do not have chronic hepatitis B without additional HBV therapy. It is unsuitable for those with significant renal impairment requiring lamivudine adjustment. If you have questions about side effects, pregnancy, or other conditions, speak with your healthcare professional.

Consider multi-month supplies when your prescriber allows them, which may reduce per-fill costs and help maintain continuity. Set refill reminders a week before you run out. Some patients compare prices for generics of individual components; however, this combination tablet is a branded product. You can also discuss patient assistance resources and whether you could buy dolutegravir lamivudine components separately if clinically appropriate, guided by your clinician.

Questions to Ask Your Clinician

• Is this regimen appropriate given my resistance test results?
• Do I need additional medication for hepatitis B management?
• How should I space doses around antacids or mineral supplements?
• What labs will you monitor, and how often?
• What side effects should prompt a call or visit?
• Could any of my current medicines interact with this therapy?
• What are my options if I miss more than one dose?

Authoritative Sources

Ready to proceed? You can place your order with prompt, express shipping and secure US shipping from Canada. This content is for general information and does not replace the advice of your healthcare professional.