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Aromasin® Tablets for Breast Cancer
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Exemestane is an aromatase inhibitor used for hormone receptor–positive breast cancer. It lowers estrogen after menopause to support ongoing therapy. Border Free Health provides US shipping from Canada so you can review options, including Exemestane without insurance.
What Aromasin Is and How It Works
Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.
Aromasin® is the brand name for an aromatase inhibitor. Exemestane blocks the aromatase enzyme and reduces estrogen production. This action may help slow estrogen-driven tumor growth in postmenopausal patients. The treatment is used as adjuvant therapy after initial tamoxifen or for advanced disease when cancer has progressed after other endocrine options. It is taken by mouth and works systemically.
This medicine is steroidal and binds irreversibly to aromatase. By reducing circulating estrogen, it can support long-term endocrine management for hormone receptor–positive disease. Discuss goals and expected course with your healthcare professional, and rely on the official label for full instructions.
Learn about condition basics in our category overview for Breast Cancer.
Who It’s For
This therapy is indicated for postmenopausal individuals with estrogen receptor–positive early breast cancer following tamoxifen, and for advanced or metastatic disease after progression on prior endocrine treatment. It is not intended for use during pregnancy or while breastfeeding. Premenopausal patients generally should not use it unless specifically directed by a specialist supervising ovarian suppression.
Those with severe liver or kidney impairment, significant osteoporosis, or a history of fractures should discuss risks, monitoring, and supportive measures. If you are exploring Exemestane online, review safety information and consult your prescriber before starting.
Some patients may transition from nonsteroidal aromatase inhibitors to this medicine or to other endocrine options such as Fulvestrant, depending on response and tolerance.
Dosage and Usage
For adults, the standard labeled schedule is one Exemestane 25 mg tablet once daily after a meal. Swallow whole with water. Taking it with food can improve absorption. Try to take it at the same time each day to maintain steady levels.
In the adjuvant setting, it may be used after 2 to 3 years of tamoxifen to complete a total of endocrine therapy as directed by your oncology team. For advanced or metastatic disease, it may be used after prior endocrine therapy has stopped working. Do not change your dose, start, or stop therapy without guidance. If uncertain, defer to the official prescribing information and your clinician’s plan.
For reliable background on treatment classes, see our broader Cancer category.
Strengths and Forms
This medicine is supplied as film-coated Exemestane 25 mg tablets for oral use. Brand and generic presentations may vary by manufacturer and packaging. Some generics are produced by well-known companies such as Teva or other approved manufacturers in different regions. Availability can differ over time and by source.
Tablets are typically dispensed in child-resistant containers. The appearance and imprint may vary across manufacturers, but potency and active ingredient remain equivalent when approved as substitutable.
Missed Dose and Timing
If you miss a dose, take it when you remember unless it is close to the next scheduled dose. If it is near the next dose, skip the missed one and continue your regular schedule. Do not double up. Consistent daily timing after a meal can help with habit formation and steady exposure.
Storage and Travel Basics
Store tablets at room temperature in a dry place, away from excess heat and moisture. Keep the container tightly closed and out of reach of children and pets. Do not store in a bathroom. Protect tablets from light as advised on the label. Keep the pharmacy label intact for identification.
When traveling, carry your medicine in original packaging along with a copy of your prescription. Use a carry-on bag when flying to avoid extreme temperatures. If crossing borders, allow extra time for security checks and keep documentation handy. For online purchases, our site uses encrypted checkout for your protection.
Benefits
As part of endocrine therapy, this medicine helps reduce estrogen, which may slow growth of hormone receptor–positive breast cancer. It is an oral, once-daily option that can be used after tamoxifen in early disease or after other endocrine agents in advanced settings. Many patients appreciate the convenience of a tablet regimen under the supervision of their oncology team.
Side Effects and Safety
- Hot flashes and sweating
- Fatigue or low energy
- Nausea or upset stomach
- Joint or muscle pain
- Headache or dizziness
- Trouble sleeping
Less common but serious effects can include bone loss or fractures, elevated liver enzymes, depression, and severe allergic reactions. Cholesterol changes may occur. Report severe or persistent symptoms to a healthcare professional. Bone health monitoring and supportive measures such as vitamin D and calcium may be considered when appropriate.
Seek urgent care for signs of a severe reaction, including swelling of the face or throat, trouble breathing, or severe rash. Always read the Medication Guide and official label before use.
Drug Interactions and Cautions
Strong CYP3A4 inducers such as rifampin, carbamazepine, phenytoin, or St. John’s wort may reduce levels of the treatment and lower effectiveness. Estrogen-containing products, including hormone replacement therapy, can counteract its benefit and generally should be avoided during therapy. Discuss all medicines, vitamins, and supplements with your prescriber.
This medicine is not recommended during pregnancy or breastfeeding. Liver disease, kidney impairment, or a history of osteoporosis may require closer monitoring. Do not combine with tamoxifen unless your oncologist specifically instructs you to switch as part of an adjuvant plan.
For additional reading on related endocrine options, see our article What Is Anastrozole.
What to Expect Over Time
Over time, reduced estrogen levels can help control hormone-driven cancer growth. Some effects, like hot flashes or joint aches, may appear early and can fluctuate. Your oncology team may monitor disease status with exams and imaging, and check bone health and labs as needed. Staying consistent with daily dosing and communicating side effects early can support adherence and allow timely adjustments to your overall care plan.
Compare With Alternatives
Nonsteroidal aromatase inhibitors, such as anastrozole or letrozole, are commonly used earlier in therapy. After progression or intolerance, clinicians may consider other endocrine strategies or targeted combinations. For HR-positive, HER2-negative metastatic disease with appropriate markers, CDK4/6 inhibitors like Kisqali or PI3K inhibitors like Piqray may be combined with endocrine therapy based on guidelines. The best option depends on stage, prior treatments, and tumor biology.
Pricing and Access
We list current Exemestane price transparently so you can compare options. US patients can order with Canadian pricing and fulfillment that Ships from Canada to US. If you are searching for an Exemestane coupon, check our site for available offers and updates.
Want to see active deals? Visit our Promotions page for current notices. For side-effect guidance written for patients, read Exemestane Side Effects.
Availability and Substitutions
Stock can vary by manufacturer and presentation. If a specific brand or bottle size is unavailable, a prescriber may recommend a suitable alternative endocrine option. If you are comparing Exemestane for sale with other endocrine therapies, review your clinician’s plan before switching.
Patient Suitability and Cost-Saving Tips
This therapy suits many postmenopausal patients with hormone receptor–positive disease under oncology supervision. It may not be appropriate for those who are pregnant, breastfeeding, or premenopausal without ovarian suppression. Discuss bone health history and other risk factors with your care team.
For savings, consider multi-month fills when appropriate, which may reduce per-fill fees and cut repeated trips. Set refill reminders on your phone or calendar to avoid gaps in therapy. If you are looking for an Exemestane discount, compare generic versus brand options and ask your prescriber about clinically acceptable substitutions.
Questions to Ask Your Clinician
- Is this the right endocrine option for my tumor biology?
- How long should I stay on therapy in my situation?
- What bone health monitoring do you recommend?
- Which side effects should I report right away?
- Could nonsteroidal aromatase inhibitors or fulvestrant be better for me?
- Do I need lab tests for liver function or cholesterol while on treatment?
- Are there drug or supplement interactions I should avoid?
Authoritative Sources
DailyMed: Exemestane Prescribing Information
Health Canada: Drug Product Database
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Can I stop taking Exemestane if I feel better?
No, continue as prescribed. Stopping early may reduce its effectiveness in preventing cancer recurrence.
Does Exemestane cause menopause-like symptoms?
Yes, because it lowers estrogen, side effects like hot flashes or night sweats are common.
Is weight gain a side effect of Exemestane?
Some women report weight gain, but it’s not guaranteed. Lifestyle and hormonal changes can contribute.
How long do I need to take Exemestane?
It is typically taken for 5 years, but your doctor may extend it based on your risk factors.
Should I take calcium or vitamin D with Exemestane?
Yes, supplements are often recommended to help protect bone health during treatment.
How does Exemestane differ from nonsteroidal aromatase inhibitors?
Exemestane is a steroidal, irreversible aromatase inhibitor. Nonsteroidal options like anastrozole and letrozole are reversible inhibitors. In practice, clinicians may sequence these agents based on response, tolerability, and treatment history. Some patients start with a nonsteroidal inhibitor and later move to a steroidal option. The choice depends on prior therapy, side effects, and guidelines for your cancer subtype. Your oncology team will determine the best approach for your situation.
Can premenopausal patients use Exemestane safely?
The medicine is indicated for postmenopausal patients. Premenopausal use is generally not recommended unless managed by a specialist with ovarian suppression. If your clinician is considering this approach, they will evaluate risks, supportive measures, and monitoring. Do not start the therapy without a clear plan from your oncology team. Review contraception needs, since the treatment can harm a developing fetus and is not for use during pregnancy.
Do I need to take Exemestane with food?
Yes. The label recommends taking your dose after a meal to improve absorption. Try to take it at the same time each day and avoid doubling up if a dose is missed. If you experience stomach upset, discuss supportive options with your clinician. Keeping a daily routine can improve adherence and help you remember each dose. Always follow the exact instructions on your prescription label.
How long is Exemestane used in early breast cancer?
Adjuvant endocrine therapy plans vary. Some regimens use tamoxifen for 2 to 3 years followed by this medicine to complete a total course as directed by your oncology team. The exact duration depends on your cancer stage, pathology, and tolerance of treatment. Do not change the plan without speaking to your prescriber. The official label and your clinician’s guidance should direct therapy length.
What monitoring might be needed during therapy?
Your clinician may check bone density, liver function tests, and cholesterol during therapy. They might recommend vitamin D and calcium if appropriate, along with lifestyle measures for bone health. Report persistent joint pain, severe hot flashes, or mood changes. Monitoring plans vary based on your medical history and concurrent medicines. Keep all scheduled visits and share any new symptoms or concerns promptly.
Can I use hormone replacement therapy while on Exemestane?
Estrogen-containing products can counteract the effect of this aromatase inhibitor. In most cases, clinicians advise avoiding hormone replacement therapy while receiving treatment. Discuss menopausal symptoms with your prescriber to consider nonhormonal options. Before starting any new medicine or supplement, review it with your healthcare professional to avoid interactions and maintain treatment effectiveness.
What if I’m also taking other cancer medicines?
Many patients receive endocrine therapy along with other agents over the course of care, but combinations depend on tumor markers and prior treatments. Some targeted drugs are paired with endocrine agents in metastatic disease under specialist guidance. Share a complete medication list with your oncology team. They will check for interactions, adjust timing if needed, and decide whether combinations are appropriate for you.
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