Naltrexone HCL 

Both are NSAIDs used to relieve pain, inflammation, and fever in conditions like arthritis, menstrual cramps, and muscle pain. They work by reducing prostaglandin production, a chemical responsible for pain and inflammation.

Take with a full glass of water and food to reduce stomach irritation, usually once or twice daily depending on the formulation. Swallow tablets whole; do not crush. Stick to the lowest effective dose for the shortest duration needed.

Stomach upset, heartburn, headache, and dizziness are frequent. Long-term use increases the risk of gastrointestinal bleeding, kidney issues, or cardiovascular problems. Contact your doctor if you see blood in stools or experience chest pain.

Yes—NSAIDs interact with other blood thinners, antihypertensives, lithium, and methotrexate, among others. Regular monitoring and dose adjustments may be necessary. Always inform your healthcare provider of all current medications.

Both are generally avoided in late pregnancy due to risks of fetal complications and labor issues. Short-term use in early pregnancy may be acceptable under a doctor’s guidance. Always consult your OB-GYN before use.