Percorten-V® Injection for Canine Addison's Disease

Percorten-V is a mineralocorticoid replacement used for dogs with Addison’s disease. It helps manage electrolytes that the adrenal glands no longer regulate well. This page explains key uses, dosing basics, safety points, and how to plan treatment smoothly.

What Percorten-V Is and How It Works

Percorten-V® replaces aldosterone-like activity to help maintain sodium and potassium balance. It is given by injection at intervals set by a veterinarian. We offer access with US delivery from Canada, which may help when availability is limited or costs are high without insurance. Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

In Addison’s disease, the body cannot retain salt or water effectively. This medicine supports fluid balance and blood pressure. It works in the background while your veterinarian adjusts any needed glucocorticoid. The class is a Desoxycorticosterone pivalate injectable suspension.

Who It’s For

This treatment is for dogs diagnosed with primary hypoadrenocorticism. The goal is to stabilize electrolytes and reduce Addisonian episodes. Many dogs remain on a schedule for long-term control.

Percorten V injection for dogs is not for animals without a confirmed diagnosis. Dogs with uncontrolled heart disease, severe kidney issues, or significant edema may require additional evaluation before use. Puppies, pregnant, or lactating dogs should be treated only under close veterinary supervision. See our condition overview in Addison Disease.

Dosage and Usage

Administration and dose are set by the veterinarian. Your prescriber typically gives the first injection and checks electrolytes to guide ongoing care. Maintenance intervals are commonly every three to four weeks, but individual needs vary.

Give only as instructed by your veterinarian. Do not change the schedule on your own. The injection is usually given intramuscularly per label. Some clinicians may individualize technique. If anything seems off with your dog’s energy, appetite, or drinking, contact the clinic promptly for guidance.

Strengths and Forms

This product is supplied as a sterile, milky suspension in a multi-dose vial. Availability may vary over time.

Common presentation: Percorten V 25 mg/mL vial. Your prescriber will determine the number of vials needed based on your dog’s weight and the maintenance interval.

Missed Dose and Timing

If a dose is missed, contact the clinic for instructions. Do not double up unless a veterinarian tells you to. Timing is important because the medicine’s effect tapers as the interval ends. Watch for recurrence of lethargy, vomiting, or collapse if the schedule has slipped. Prompt veterinary advice helps protect your dog’s stability.

Storage and Travel Basics

Store vials at room temperature per label. Keep them upright, tightly closed, and away from children or pets. Do not freeze the suspension. Shake the vial as directed before withdrawing the dose to re-suspend contents evenly.

When you travel, pack the vial in a protective case and keep it out of direct heat. Bring the prescription label and your veterinarian’s contact details. For longer trips, ask the clinic about timing the next injection, needed supplies, and documentation for airlines or hotels. Our checkout is encrypted, and your order history helps you manage refills across trips.

Benefits

This therapy supports normal hydration and electrolyte balance in dogs with Addison’s disease. It can reduce crisis risk when used with appropriate monitoring. Many caretakers find a predictable injection interval easier than daily tablets.

An exact match for the class is DOCP injection for dogs. It provides mineralocorticoid support while a separate glucocorticoid handles day-to-day stress needs. Consistency with appointments and lab checks helps maintain steady control.

Side Effects and Safety

Most dogs tolerate therapy well. Some effects relate to fluid and electrolyte changes as the dose is fine-tuned.

• Thirst and urination changes
• Reduced appetite or digestive upset
• Lethargy or restlessness
• Injection site discomfort
• Mild swelling from fluid retention

Contact the clinic if vomiting, diarrhea, collapse, severe weakness, facial swelling, or hives occur. Dogs with heart disease or kidney problems may be more sensitive to fluid shifts. A clinician will guide monitoring to reduce risks. Information on Percorten side effects in dogs is based on label experience and veterinarian reports.

Drug Interactions and Cautions

Tell your veterinarian about all medicines and supplements your dog receives. Interactions can occur with drugs that affect electrolytes or fluid balance, including diuretics, ACE inhibitors, or certain heart medicines. Nonsteroidal anti-inflammatory drugs may require caution in sensitive dogs. Steroids are often used alongside this therapy; dosing is individualized by the prescriber.

Always bring your dog’s full medication list to appointments. Electrolyte changes can alter how other medicines work. Do not start or stop therapies without veterinary guidance.

What to Expect Over Time

The aim is steady control, not a dramatic change overnight. Your veterinarian may check sodium and potassium after the initial dose and during maintenance. Over time, many dogs settle into a reliable interval that fits their routine. Keep a log of behavior, appetite, water intake, and bathroom habits. These notes help the clinic interpret lab results and refine the plan.

Consistency with feeding, routine, and stress management also supports stability. If your dog faces surgery, illness, or travel, your veterinarian may adjust supportive medications temporarily.

Compare With Alternatives

Another mineralocorticoid option is Zycortal®, which contains the same active class. The label route and handling can differ, so follow your prescriber’s direction. In some dogs, veterinarians may instead consider fludrocortisone tablets, usually with a glucocorticoid, based on medical history and response.

Ask your clinic which option suits your dog’s condition, concurrent illnesses, and caregiver preferences. Both injectable options require regular electrolyte checks and consistent follow-up.

Pricing and Access

We help you compare options backed by Canadian dispensing. You can review availability, see current pricing, and place an order when your veterinarian has prescribed it. Our catalog also includes other Pet Medications when your dog needs coordinated care.

For budgeting, you can ask your clinic how many injections a vial will cover at the current dose. We support US shipping from Canada to simplify access for U.S. pet families. See site Promotions for occasional offers, then compare your options. Talk with the clinic if you have questions about Percorten V cost and refill timing.

Availability and Substitutions

Stock can vary by manufacturer supply and demand. If an item is unavailable, your prescriber may recommend a suitable alternative or adjust the plan temporarily. Our team can help you search the catalog, including country-of-origin details such as Canada, to find a match for your prescription and timeline.

Patient Suitability and Cost-Saving Tips

Good candidates are dogs with confirmed Addison’s disease whose clinicians plan regular electrolyte monitoring. Dogs with congestive heart failure, severe kidney disease, or uncontrolled hypertension may need a different approach. Your veterinarian will evaluate coexisting conditions before starting treatment.

To manage costs, consider multi-month planning when safe, and set refill reminders in your account. You can keep a treatment calendar that aligns injections with lab checks. Ask your clinic about timing vials to reduce waste. For broader dog care reading, see Cardalis For Dogs and our article Guide To Insulin For Dogs.

Questions to Ask Your Clinician

• Initial plan: What dose and interval are we starting with?
• Monitoring: When should electrolytes be checked after the first dose?
• Route: Is my dog receiving IM injections per label, or a clinic-specific approach?
• Glucocorticoid: What daily steroid and dose will accompany this therapy?
• Warning signs: Which symptoms mean we should call immediately?
• Supplies: Which syringes and needles fit the vial and dose volume?
• Travel: How should we store and carry the vial during trips?

Authoritative Sources

FDA Green Book Listing

DailyMed/Labeling Database

Health Canada Drug Product Database

Ready to proceed? You can order with prompt, express shipping, plus temperature-controlled handling when required. Always use exactly as prescribed and follow your veterinarian’s advice. This page is informational and is not a substitute for professional veterinary guidance.