Tradjenta

How does Trajenta work?

Tradjenta belongs to a group of widely used antidiabetic drugs known as DPP -4 inhibitors. These drugs aid in the regulation of insulin levels, particularly after meals when blood glucose levels are high, as well as the reduction of blood sugar levels caused by the body’s own production of sugar. By blocking the breakdown of certain hormones involved in the metabolism of food and insulin regulation, Tradjenta allows for the release of more insulin from the pancreas’ beta cells while simultaneously delaying the release of glucagon, which prevents further increases in blood glucose levels. Generally, in combination with a nutritious diet and regular physical activity, Tradjenta can help the body generate more insulin and reduce blood glucose levels.

Tradjenta, also known as Linagliptin or Tradjenta 5 mg, is an oral antidiabetic drug developed to treat type 2 diabetes mellitus. The active ingredient in Tradjenta is a generic medicine known as DPP-4 inhibitor, which is part of the gliptin group of antidiabetes drugs. This drug is used in combination with a healthy diet and exercise to improve blood sugar regulation in adults with diabetes mellitus. It should not be used on its own or in combination with other blood glucose-lowering drugs. Additionally, it should not be used in the treatment of type 1 diabetes, nor should it be used in combination with other antidiabetes drugs for the prevention of diabetic ketoatacidosis.

Precautions and Warnings

Tradjenta can cause severe, life-threatening pancreatitis (inflammation of your pancreas). Stop taking Tradjenta and call your doctor at once if you have pain in your upper stomach that may spread to your back, with or without vomiting.

Also call your doctor if you have symptoms of heart failure, such as swelling, rapid weight gain, or shortness of breath (even while lying down).

You should not use linagliptin if you have diabetic ketoacidosis (call your doctor for treatment).

Before you take Tradjenta, tell your doctor if you have high cholesterol or triglycerides, or a history of pancreatitis.

Tradjenta is only part of a complete program of treatment that may also include diet, exercise, weight control, foot care, eye care, dental care, and testing your blood sugar. Follow your diet, medication, and exercise routines very closely. Changing any of these factors can affect your blood sugar levels.

Dosage

Follow the dosage recommended by your doctor. The usual dosage is usually  5 mg tablet, once daily with or without food.

Side Effects

Common Side Effects:

• Low blood sugar (hypoglycemia)
• Throat inflammation
• Severe allergic reaction (hypersensitivity)
• Cough
• Joint pain
• High blood triglycerides
• Swelling of the face

Rare Side Effects

• Pancreas inflammation
• Mouth infection