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Does Abilify Cause Weight Gain? Understanding Its Impact on Your Body

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Written by BFH Staff Writer on September 12, 2024

Does Abilify Cause Weight Gain? Understanding Its Impact on Your Body
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Taking Abilify for conditions like schizophrenia, bipolar disorder, or depression often comes with some questions about side effects. One of the most common concerns is whether Abilify can lead to weight gain. Let’s explore how this medication might impact your weight and what you can do to stay ahead of it.

What Abilify Does to Your Body

Abilify (aripiprazole) is a common medication used to balance certain chemicals in the brain, particularly dopamine and serotonin, to help manage mental health conditions. While it can be a game-changer for many, there are a few side effects that people often talk about, and weight gain is one of them. So, let’s dive into how Abilify might play a role in weight changes.

Why Some People Experience Weight Gain with Abilify

Yes, weight gain can happen with Abilify, but it’s not the same for everyone. There are a few reasons this might happen, and we’ll walk through the most common ones.

Increased Appetite

One reason you might notice the scale creeping up is that Abilify can make you feel hungrier. It has a way of messing with your hunger signals, leading you to crave food more often or eat bigger portions. When you’re eating more than usual, it’s pretty easy to see how the pounds can start to add up.

Slowed Metabolism

Abilify can also slow down your metabolism, meaning your body doesn’t burn calories as efficiently as it used to. A slower metabolism plus a bigger appetite? Well, that’s a recipe for weight gain right there. And if you’re already someone who struggles with keeping your metabolism up, you might notice this even more.

Reduced Physical Activity

For some people, taking Abilify can cause fatigue or make you feel a little sluggish. If you’re feeling more tired than usual, it’s easy to see how you might be less active. And when you’re not moving around as much, your body isn’t burning off those extra calories, which can result in weight gain over time.

How Abilify Affects Your Metabolism

There’s more to it than just eating more or moving less. Abilify can also change the way your body handles metabolism, leading to a few other reasons why weight gain might happen.

Insulin Resistance

One way Abilify affects your metabolism is by altering how your body processes insulin. Insulin is a hormone that helps regulate your blood sugar, but when Abilify throws off your insulin balance, your body can start storing more fat, especially around your stomach area. This condition, called insulin resistance, can make it harder for your body to burn fat, leading to weight gain.

Changes in Fat Storage

Abilify doesn’t just make you eat more—it can actually change how your body stores fat. You might notice extra fat building up in areas like your waistline, even if your diet hasn’t changed all that much. It’s frustrating, but it’s all part of how your body is reacting to the medication.

Lower Energy Levels

Abilify might leave you feeling less energetic, which can make staying active harder. When your energy dips, it’s tempting to skip the gym or spend more time on the couch. Unfortunately, that lack of movement makes it easier for those extra calories to stick around as weight gain.

How Weight Gain on Abilify Happens

So, not everyone gains weight on Abilify, but for those who do, it can happen gradually or all at once. Let’s take a look at what influences this and how it might play out over time.

Why It’s Different for Everyone

Not every person on Abilify gains weight, and even when they do, the amount can vary. Some people may only gain a couple of pounds, while others might notice a bigger change. Factors like your age, genetics, and activity level can influence how your body responds to the medication. Additionally, it’s important to consider how lifestyle factors, such as the interaction between Abilify and alcohol, might affect weight and overall health.

Short-Term vs. Long-Term Weight Gain

You might not notice any changes right away, but over the long haul, weight gain can sneak up on you. Even if you’re gaining just a little bit each month, it adds up over time. That’s why it’s a good idea to keep an eye on your weight and talk to your doctor if it starts to become a concern.

How Abilify Compares to Other Antipsychotics

If you’re worried about weight gain, you might be relieved to know that Abilify tends to cause less weight gain compared to other antipsychotics. Medications like olanzapine and quetiapine are known to cause more significant weight changes. While Abilify isn’t completely free of this side effect, it’s usually a better option if weight gain is something you’re concerned about.

Wrapping It Up

Abilify can be an important tool in managing mental health conditions, but like with any medication, it can come with some side effects. Weight gain is something that may happen, but it’s not guaranteed. The key is to stay informed, keep an eye on any changes, and have open conversations with your healthcare provider. By working together, you can find a way to manage your treatment while keeping your health goals on track.

Frequently Asked Questions (FAQs)

Does everyone on Abilify gain weight?

No, not everyone on Abilify will gain weight. The effect varies from person to person, and some people may not see any change in their weight at all. It really depends on how your body reacts to the medication, so it’s important to monitor any changes and talk to your doctor if you have concerns.

Can I avoid gaining weight while on Abilify?

While you might not be able to avoid it completely, there are things you can do to reduce the chances of gaining weight. Staying active, eating balanced meals, and keeping an eye on your portions can help keep things in check. It’s also a good idea to talk to your doctor about ways to manage any weight changes. 

Should I stop taking Abilify if I gain weight?

It’s never a good idea to stop taking any medication without talking to your doctor first. If weight gain is becoming a concern, your doctor may be able to adjust your dosage or suggest other ways to help manage the weight. But stopping the medication on your own could make your symptoms worse, so it’s best to work with your healthcare provider on a plan. 

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