Creon® Capsules for Exocrine Pancreatic Insufficiency

Pancrelipase delayed-release capsules help your body digest fat, protein, and carbs. Here you’ll find plain guidance on dosing, safety, and how to arrange US delivery from Canada. We also outline Creon® price without insurance so you can budget before you order.

What Creon Is and How It Works

Creon® contains pancreatic enzymes from porcine sources. The capsules use enteric-coated microspheres that pass the stomach and release enzymes in the small intestine. Lipase, protease, and amylase then work with your meal to break down fats, proteins, and carbohydrates. This helps manage the symptoms of Exocrine Pancreatic Insufficiency like oily stools, cramping, and bloating.

Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

This treatment is taken with food, not on an empty stomach. The delayed-release design helps reduce enzyme breakdown by stomach acid so more reaches the intestines. Your prescriber will individualize the total dose based on symptoms, diet, and body weight.

Who It’s For

This medicine is indicated for adults and children with exocrine pancreatic insufficiency related to cystic fibrosis, chronic pancreatitis, or following pancreatic surgery. It can also be used for other conditions that cause pancreatic enzyme deficiency when prescribed by a clinician.

People with a known allergy to pork proteins or any capsule components should avoid it. During an acute pancreatitis flare, use is typically paused until your prescriber advises restarting. Discuss your history of gout, kidney issues, or high uric acid before beginning therapy.

Learn more about these conditions: Chronic Pancreatitis and Cystic Fibrosis.

Dosage and Usage

Take the capsules with every meal and snack as directed. Many people use a larger dose with meals and a smaller amount with snacks. Swallow capsules whole with liquid. If you cannot swallow them, carefully open the capsule and sprinkle the contents on a small amount of soft, acidic food such as applesauce. Swallow the mixture without crushing or chewing the granules, then drink water to clear your mouth.

Do not add the granules to milk, infant formula, or alkaline foods. Avoid chewing the granules, as this can irritate the mouth or reduce effectiveness. If your eating pattern changes, talk to your prescriber about adjusting the plan. For broader digestive topics, see our Gastrointestinal collection.

Strengths and Forms

The treatment comes as delayed-release capsules in multiple strengths for flexible dosing, such as 12,000 and 36,000 lipase units per capsule. Availability may vary by pharmacy and manufacturer lots.

Missed Dose and Timing

If you forget a dose with a meal or snack, take it as soon as you remember with the food. If the meal is over, skip the missed amount and resume at the next meal or snack. Do not double up or take this medicine on an empty stomach to “catch up.” Keep your dosing linked to food for best results.

Storage and Travel Basics

Store the bottle at room conditions in a dry place. Keep the cap tightly closed, and protect the granules from moisture and heat. Do not transfer the contents to another container. Keep all medicines out of reach of children and pets.

For travel, keep the labeled bottle in your carry-on. Pack enough for your trip plus a buffer in case plans change. Bring a copy of your prescription or prescriber contact details. If your supply is sourced from Canada, carry the original label for security screening and medication reconciliation.

Benefits

Consistent use with meals can reduce greasy stools and abdominal discomfort. Many people notice less urgency, fewer bathroom trips, and improved stool form. The delayed-release design supports enzyme delivery where digestion occurs. Capsule options allow tailoring to different meal sizes, eating patterns, and ages.

Side Effects and Safety

• Stomach pain or cramping
• Gas and bloating
• Constipation or diarrhea
• Nausea
• Headache
• Cough or throat irritation

Serious but uncommon risks include fibrosing colonopathy, especially with very high daily doses for prolonged periods. Mouth irritation can occur if granules are chewed. Allergic reactions may involve rash, swelling, or breathing difficulty; seek immediate care if these occur. Elevated uric acid can happen in some people; your clinician may monitor if you have gout or kidney concerns. For more on risk discussions, see Long Term Side Effects.

Drug Interactions and Cautions

This therapy has few known drug interactions. Let your prescriber know if you take acid-reducing medicine, as this may affect how some pancreatic enzyme products are used. Do not change doses of any treatment without medical guidance. Report persistent abdominal pain, unusual constipation, or new gastrointestinal bleeding to a healthcare professional promptly.

What to Expect Over Time

With consistent use at meals and snacks, many people experience steadier digestion and fewer greasy stools. Your prescriber may adjust the plan based on symptoms and dietary intake. Keeping a food and symptom journal can help fine-tune the regimen. If symptoms return when you eat larger meals or higher-fat foods, discuss whether your dosing around those meals should be revisited.

Digestive health is dynamic. Aging, diet, and comorbid conditions all play a role. For context on broader gut wellness, visit Gut Health Aging.

Compare With Alternatives

Multiple pancrelipase products are approved and may be appropriate. One alternative we carry is Viokace, a non–enteric-coated pancrelipase tablet that is used with a proton pump inhibitor when prescribed. Other brands such as Pancreaze or Zenpep may be considered by clinicians based on dosing needs, food preferences, and tolerability. Your prescriber can help you choose a product and plan that aligns with your diagnosis and daily routine.

Pricing and Access

Canadian pricing with US delivery from Canada helps many patients plan therapy more confidently. Review the product page to compare quantities and capsule strengths, then follow the checkout steps to upload your prescription. Our checkout uses encrypted processing to protect your information.

To see current Creon price options, view the item listing and select your preferred count. For those comparing access models, Pancrelipase from Canada is part of our cross-border service. If you are seeking coupons, check our current Promotions and speak with your prescriber or insurer about any program requirements.

Availability and Substitutions

Supply can vary by strength and package size. If a specific capsule is unavailable, your prescriber may recommend an equivalent enzyme total using multiple capsules or a different brand. There is no approved Creon generic in the United States at this time. Your pharmacy team will contact you and your clinician if a substitution is proposed and obtain approval before dispensing.

Patient Suitability and Cost-Saving Tips

Good candidates are people with diagnosed exocrine pancreatic insufficiency who can coordinate doses with meals and snacks. Those with pork allergy or during an acute pancreatitis flare should avoid use unless a prescriber specifically directs otherwise.

• Multi-month fills: reduce per-fill fees and simplify travel planning
• Meal plans: keep a simple dosing schedule aligned to your eating pattern
• Refill reminders: set calendar alerts before you run low
• Food journal: track meals, symptoms, and dose timing to refine therapy
• Insurance review: confirm coverage criteria and any prior authorization needs

For background on evolving access and affordability topics, see Canadian Drug Importation.

Questions to Ask Your Clinician

• Which meal sizes need the highest enzyme totals for me?
• Can I sprinkle the granules, and on which foods is that acceptable?
• How should I handle days with frequent snacks or high-fat meals?
• What signs suggest I need a dose review or different product?
• Are there reasons to avoid acid-reducing medicines with this therapy?
• Could any lab monitoring help, such as fat-soluble vitamin levels?
• How should I plan for Pancrelipase medication price if my coverage changes?

Authoritative Sources

Manufacturer Prescribing InformationFDA DailyMed LabelHealth Canada Drug Product Database

Ready to proceed? Add to your cart and complete checkout with prompt, express shipping and US shipping from Canada. Prescription required; temperature-controlled handling when required. This page is informational and not a substitute for medical advice.