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Glenza® Capsules for Prostate Cancer
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This medicine is a hormonal therapy for advanced prostate cancer. It works by blocking androgen receptor signaling to slow disease progression and reduce cancer activity.
What Glenza Is and How It Works
Glenza® contains enzalutamide, an androgen receptor inhibitor used in several stages of advanced prostate cancer. With US shipping from Canada available, many patients compare options and cash-pay choices without insurance before ordering. Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.
Each Glenza capsule targets the androgen receptor pathway. The treatment binds the receptor and reduces the effect of androgens on tumor cells. It can help delay progression, improve disease control, and support quality of life measures. The medicine is taken by mouth and is typically used long term under a prescriber’s supervision.
Who It’s For
Enzalutamide capsules are used for adults with metastatic castration-resistant prostate cancer, non-metastatic castration-resistant disease, and metastatic castration-sensitive prostate cancer. A gonadotropin-releasing hormone (GnRH) analog is usually continued if the patient has not had surgical castration. This medicine is not indicated for use in women or children. It should be avoided in pregnancy due to embryo-fetal risk with exposure.
People with a history of seizures, significant head injury, brain tumors, or conditions that increase seizure risk should discuss suitability with their healthcare professional. Those with severe liver impairment require careful evaluation. Your prescriber will consider interactions and your overall treatment plan.
Dosage and Usage
The typical labeled regimen is once daily by mouth, at roughly the same time each day. Many regimens use a total daily amount equivalent to 160 mg, as directed by the official labeling. Swallow capsules whole with water. Do not open, crush, or chew. The medicine may be taken with or without food.
Continue concomitant androgen deprivation therapy if indicated. If you are also receiving a GnRH analog, do not stop it unless your prescriber advises otherwise. If vomiting occurs after a dose, do not take an extra dose; take the next scheduled dose at the usual time. If a caregiver handles capsules, standard safe-handling practices are prudent.
Never change your regimen on your own. When uncertain, follow the full prescribing information or ask a healthcare professional to review the label directions.
Strengths and Forms
The product is commonly supplied as oral capsules. A frequently dispensed presentation includes 40 mg capsules in bottles or blisters, depending on manufacturer packaging and market. Availability, packaging, and pack sizes can vary by batch and sourcing.
Country-of-origin details for some lots are noted on the product page. You can also browse items sourced from India or explore our broader therapeutic catalog under Other.
Missed Dose and Timing
If you miss a dose, take it as soon as you remember on the same day. If an entire day is missed, skip the missed dose and take the next dose at the usual time the following day. Do not take two doses at once to make up for a missed dose. If you are unsure what to do after multiple missed doses, consult the official label or your prescriber.
Storage and Travel Basics
Store capsules at room temperature in the original container with the lid closed. Keep the medicine dry and away from excessive heat or direct light. Do not store in a bathroom. Always keep out of reach of children and pets.
For travel, carry the labeled container in your hand luggage. Bring a copy of your prescription and a medication list when flying. Keep dosing consistent across time zones based on your daily schedule; your prescriber can help plan adjustments if needed. Dispose of unused medicine according to local guidance or your pharmacy’s take-back program.
Benefits
This therapy can help lower prostate-specific antigen (PSA) levels and slow progression in appropriate settings. It may reduce the risk of metastasis in non-metastatic castration-resistant disease when used per labeling. In metastatic disease, the treatment can help delay clinical progression. Oral dosing provides at-home convenience and can fit into combination regimens that your oncology team coordinates.
Side Effects and Safety
- Common: fatigue, hot flashes, dizziness, headache
- Musculoskeletal: joint discomfort, back pain, falls
- Gastrointestinal: decreased appetite, constipation, diarrhea
- Cardiovascular: high blood pressure, edema
- Neurologic: sleep disturbances, anxiety
Serious risks can include seizures, posterior reversible encephalopathy syndrome, falls and fractures, hypertension complications, and rare hypersensitivity. Embryo-fetal toxicity is a known risk with exposure during pregnancy. Contact a healthcare professional urgently if you experience seizure, severe headache with vision changes, chest pain, or signs of stroke. Review the full safety profile in the official prescribing information before starting.
Drug Interactions and Cautions
This medicine can affect other drugs by inducing CYP3A4 and, to a lesser extent, CYP2C9 and CYP2C19. Sensitive substrates of these enzymes may have reduced exposure. Caution is advised with narrow therapeutic index medicines metabolized by these pathways. Strong CYP2C8 inhibitors and inducers can alter enzalutamide exposure; your prescriber will determine if adjustments or alternatives are needed.
Use caution with medicines that lower seizure threshold, such as certain antidepressants, antipsychotics, or tramadol. Discuss all prescriptions, over-the-counter medicines, and supplements with your oncology team so they can screen for interactions on your behalf.
What to Expect Over Time
Early on, some patients notice fatigue or hot flashes as their body adjusts. Blood tests such as PSA and liver enzymes are checked periodically. Imaging may be scheduled to assess response. Symptom changes can be gradual. Staying on a consistent daily schedule helps maintain steady levels. If side effects bother you, your healthcare professional can discuss supportive strategies guided by the label and clinical practice standards.
Over the longer term, adherence is key. Set reminders, use a pill organizer, and keep regular follow-up appointments. If your oncology plan changes, your prescriber will revisit risks, benefits, and whether to continue or transition to another therapy.
Compare With Alternatives
Prescribers may consider other androgen receptor pathway options based on cancer stage and prior therapy. These may include abiraterone acetate with corticosteroid support, apalutamide, or darolutamide. The branded reference product for enzalutamide, Xtandi, is another option some patients receive when appropriate. Your oncology team will weigh medical history, comorbidities, and goals of care when selecting the most appropriate regimen.
For additional oncology background and supportive information, see these resources: Exemestane Side Effects, Fulvestrant Injection, and Aromasin vs Arimidex. For general online pharmacy guidance, review Order Medications Online Safety.
Pricing and Access
We display the Glenza price transparently on the product page with current availability notes. Canadian pricing with US delivery from Canada helps many compare cash-pay options to local pharmacy quotes. For those paying out of pocket, we also note typical enzalutamide cost without insurance to support budgeting.
You can check live availability, add to cart, and proceed through encrypted checkout. For occasional site promotions, visit our Promotions page. If the item is temporarily unavailable, you can message support for alternatives your prescriber might consider.
Availability and Substitutions
Supply can vary by batch and manufacturer. If the capsule strength or pack size you need is not listed, a prescriber may recommend a comparable formulation or a different androgen receptor pathway option. We cannot provide restock dates. Your care team can advise whether to continue, pause, or switch therapies based on your clinical status.
Patient Suitability and Cost-Saving Tips
This therapy is intended for adult men with eligible prostate cancer types as outlined in the label. It is not used in women or pediatric patients. Those with seizure risk, significant liver disease, or uncontrolled hypertension will need careful evaluation. Handling precautions may apply for caregivers.
To manage ongoing costs, consider multi-month fills when appropriate, since fewer refills can reduce per-shipment fees. Setting calendar reminders helps prevent gaps in therapy. Understanding the Price of Glenza can support planning with your care team and pharmacy. If your clinician expects long-term use, ask about synchronizing refill dates with other medicines to simplify scheduling.
Questions to Ask Your Clinician
- Suitability: Is this therapy appropriate for my cancer stage and history?
- Goals: What outcomes are realistic with this treatment plan?
- Safety: Which side effects should prompt a call right away?
- Interactions: Do any of my medicines or supplements conflict with this therapy?
- Monitoring: How often will we check labs and imaging?
- Logistics: Should I continue my GnRH therapy while taking this medicine?
Authoritative Sources
Manufacturer Prescribing InformationFDA DailyMed: EnzalutamideHealth Canada Drug Product Database
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What is Glenza used for?
Glenza (Enzalutamide) is prescribed for prostate cancer. It works by blocking the effects of testosterone, which slows the growth and spread of cancer cells.
How long does it take for Glenza to show results?
Most patients begin to see improvements within a few months of starting treatment. However, the effectiveness varies depending on the cancer stage and individual response.
Can Glenza cause fatigue?
Yes, fatigue is one of the most common side effects. Getting adequate rest and maintaining a healthy diet to manage energy levels is recommended.
Are there dietary restrictions while taking Glenza?
While no specific nutritional restrictions exist, a balanced diet can support overall health during treatment. Alcohol should be avoided as it may increase the risk of side effects.
Does Glenza affect mental function?
Some patients report memory issues, dizziness, or difficulty concentrating. If these symptoms worsen, consult your doctor about adjusting the treatment plan.
How is this medicine different from chemotherapy?
This therapy is a hormone treatment that blocks androgen receptor signaling. It is not a cytotoxic chemotherapy. It is taken by mouth and often used alongside continuous androgen deprivation therapy. Some people still receive other systemic medicines, radiation, or surgery as part of a comprehensive plan. Your oncology team will decide the best combination based on your cancer stage, prior treatments, and overall health profile.
Can I take it with food or do I need to avoid certain meals?
You can take the capsule with or without food. Try to take it at the same time each day for consistency. Grapefruit or special meal timing is not generally required in the labeling for this treatment, but interactions with other medicines can be important. Keep a list of all medicines and supplements and ask a clinician to check for interactions when starting or stopping any product.
What if I forget a dose or vomit after taking it?
If you miss a dose, take it as soon as you remember the same day. If you miss the whole day, skip it and take the next dose at your usual time the following day. Do not double up. If you vomit after a dose, do not take an extra dose. Resume at the next scheduled time. If you have frequent vomiting, contact your healthcare professional for guidance.
How long will I need to stay on this treatment?
Duration varies. Many patients remain on therapy as long as it is working and tolerable, per the label and their clinician’s guidance. Your team will monitor PSA, symptoms, and imaging. They may continue, pause, or change therapy if progression or side effects occur. Avoid changing or stopping treatment on your own. Ask your prescriber about monitoring intervals and criteria for continuing.
What side effects should I watch for at home?
Common effects include fatigue, hot flashes, dizziness, decreased appetite, and blood pressure changes. Falls and fractures can occur, especially in older adults. Rare but serious problems include seizures and posterior reversible encephalopathy syndrome. Seek urgent care for seizure, severe headache with vision changes, chest pain, or stroke symptoms. Your clinician can suggest supportive strategies if routine side effects persist.
Can it interact with my other medications?
Yes. The therapy can increase the metabolism of many drugs by inducing CYP3A4 and to a lesser extent CYP2C9 and CYP2C19. Sensitive substrates, such as certain blood thinners, anti-seizure drugs, or antiplatelets, may require careful review. Strong CYP2C8 modifiers can affect exposure. Share a complete medication and supplement list with your prescriber to evaluate interactions.
How should I store it and travel with it?
Store capsules at room temperature, dry, and in the original container. Keep away from heat, moisture, and light. During travel, keep the labeled bottle in your carry-on. Bring your prescription or a medication list. Maintain a consistent daily schedule across time zones when possible. Do not transfer capsules into unlabeled bags or organizers when crossing borders; keep original labeling visible.
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