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Xalacom® Ophthalmic Solution for Open-Angle Glaucoma
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Latanoprost/timolol are combination eye drops that lower eye pressure. You can get Latanoprost Timolol without insurance, with US delivery from Canada. This page explains how the medicine works, who it suits, and safe use basics.
What Xalacom Is and How It Works
Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.
This medicine combines a prostaglandin analog and a beta blocker. It targets high pressure inside the eye, which can strain the optic nerve. Ophthalmology care teams often consider it when a single agent is not enough.
Latanoprost increases the outflow of fluid from the eye. Timolol reduces fluid production. Together, they lower intraocular pressure to help protect vision over time. The fixed-dose format reduces the number of bottles and doses compared with separate products. Many people use it for Open Angle Glaucoma or Ocular Hypertension. Xalacom® is one reference brand for the latanoprost/timolol combination. Some patients and prescribers may prefer Latanoprost/Timolol Ophthalmic Solution over separate bottles for simplicity.
Who It’s For
This treatment is indicated to reduce elevated eye pressure in open-angle glaucoma and ocular hypertension. It may be considered when one agent alone does not achieve targets. People with a history of asthma, severe COPD, slow heart rate, or heart block may need alternatives because of the timolol component. Contact lens users should remove lenses before dosing and wait to reinsert as directed on the label.
Those who have had herpetic keratitis, active eye infection, or certain ocular surgeries should discuss risks with a clinician. Latanoprost Timolol drops for glaucoma can be effective, but suitability remains individual and guided by your prescriber.
Dosage and Usage
Use exactly as directed on the official label and by your prescriber. The usual schedule is one drop in the affected eye or eyes once daily, often in the evening. Do not use more than once daily, as extra doses may reduce effectiveness.
Administration tips:
- Wash hands, tilt head back, and gently pull down the lower eyelid.
- Hold the bottle above the eye without touching lashes or skin.
- Instill one drop, then close the eye and gently press the inner corner for 1–2 minutes.
- Wait at least 5 minutes before any other eye medication.
- Remove soft contact lenses before use; reinsert as directed after dosing.
If vision blurs right after dosing, wait for clarity before driving or operating machinery. Always follow the package insert for detailed steps.
Strengths and Forms
The combination is typically supplied as preserved multi-dose bottles. Availability may vary by manufacturer and market.
- Latanoprost Timolol 2.5 mL bottle
- Latanoprost/timolol fixed-dose drops at 0.005%/0.5% concentration
- Some markets also offer 5 mL bottles; check local availability
Packaging, excipients, and cap colors can differ by supplier. If you have preferences about preservatives or bottle size, discuss options with your prescriber.
Missed Dose and Timing
If you miss a dose, take the next dose at the usual time. Do not double up. If you apply drops close together, excess medication may spill and reduce effectiveness. Aim for consistent dosing at the same time each day for best results.
Storage and Travel Basics
Store as directed on the carton and leaflet. Many latanoprost-containing drops are kept refrigerated before first opening, then can often be stored at room temperature for a limited period. Protect from light. Keep the cap tightly closed and the tip clean.
When traveling, pack your bottle in a protective case. Carry a copy of your prescription if flying. Avoid leaving drops in a hot car or in freezing conditions. As a general micro-cue for quality, our partners use temperature-controlled handling when required. Discard the bottle by the labeled beyond-use date after opening.
Benefits
This combination reduces intraocular pressure by two complementary mechanisms. It may help simplify routines by combining two agents in one bottle. Fewer bottles can mean fewer instillations and less confusion about schedules. For some people, that convenience supports better adherence.
With consistent use, many patients notice steadier pressures at follow-up visits. The treatment can limit exposure to multiple preservatives versus separate products, depending on your prior regimen. Your results depend on diagnosis, baseline pressure, and response.
Side Effects and Safety
Common effects can include mild eye irritation, burning or stinging on instillation, red eyes, dry eye sensation, and blurred vision right after dosing. Darkening of the iris, eyelid skin changes, and increased eyelash growth may occur with prostaglandin analogs.
Because timolol is a beta blocker, systemic effects may include slower heart rate, fatigue, or shortness of breath in susceptible individuals. Rare but serious reactions include severe breathing difficulty, chest pain, signs of infection, sudden vision changes, or swelling of the face or throat. Seek urgent care for severe reactions. Always report new or worsening symptoms to your healthcare professional.
Drug Interactions and Cautions
Tell your prescriber about all eye and oral medicines you use. Using multiple prostaglandin analogs at the same time can reduce effectiveness. Beta blockers may interact with oral beta blockers, certain calcium channel blockers, antiarrhythmics, or digoxin, leading to additive cardiovascular effects.
People with asthma, severe COPD, bradycardia, heart block, or heart failure should review risks of ocular beta blockers. Contact lens wearers should remove lenses before dosing because preservatives can be absorbed by soft lenses. If you have significant ocular surface disease, ask about preservative-free options such as Latanoprost singles or alternatives discussed below.
What to Expect Over Time
Your clinician monitors eye pressure to assess response. Many people see pressure changes after starting therapy, with stabilization over ongoing use. Keep all follow-up visits so your care team can adjust treatment if targets are not met.
If the therapy works well and is tolerated, it may continue long term. If pressures remain above goal or side effects occur, your prescriber may switch to a different agent or add therapy. Educational resources like Why Is Azopt So Expensive can help you understand class options and discussions about costs.
Compare With Alternatives
Other combination drops may be considered if this product is not suitable. Combigan pairs brimonidine with timolol and is typically dosed twice daily. Dorzolamide Timolol combines a carbonic anhydrase inhibitor with timolol and is also commonly used twice daily.
For those who need a single-agent prostaglandin instead, options include Travatan Z, Lumigan Rc, Vyzulta, or Xalatan, depending on individual response and tolerance.
Pricing and Access
Many patients look for Latanoprost Timolol Canadian pricing when paying out of pocket. We provide transparent options aligned with US shipping from Canada. You can compare choices and talk with your prescriber about suitable fills.
If you need coupons, see current offers on our Promotions page. For some, Latanoprost Timolol US shipping supports steady access when local supplies vary. Check availability on this page and complete checkout when your prescription is ready.
Availability and Substitutions
Supply can vary by manufacturer. If the product you want is unavailable, a prescriber may recommend an alternative. The Generic Xalacom ophthalmic solution may be substituted when appropriate and approved by your clinician. Never switch without professional guidance.
Patient Suitability and Cost-Saving Tips
This therapy may suit adults with open-angle glaucoma or ocular hypertension who need additional pressure lowering from a two-mechanism drop. It may not suit those with asthma, significant pulmonary disease, severe cardiac conduction problems, or those who cannot tolerate prostaglandin effects.
- Multi-month fills: Ask about 60- or 90-day supplies to reduce trips.
- Refill reminders: Set calendar alerts to prevent gaps in therapy.
- Consistency: Dose at the same time daily to aid adherence.
- Plan ahead: Order a refill before your bottle runs low.
- Follow-up: Keep eye pressure checks as scheduled.
For single-agent alternatives, discuss Latanoprost or other prostaglandins mentioned above. Your prescriber can tailor a plan based on targets, side effects, and exam findings.
Questions to Ask Your Clinician
- Is once-daily dosing right for my eye pressure targets?
- Should I use punctal occlusion to reduce systemic absorption?
- How long after opening should I keep this bottle?
- Can I wear soft contacts, and when can I reinsert them?
- What signs of side effects should I watch for and report?
- Could a single-agent prostaglandin or another combo be a better fit?
- How often should I return for pressure checks and visual fields?
Authoritative Sources
Pfizer Canada Product Monographs
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What is Latanoprost/Timolol Ophthalmic Solution used for?
This combination eye drop is used to lower intraocular pressure in patients with glaucoma or ocular hypertension who require multiple medications. It combines the benefits of latanoprost, which increases fluid outflow, and timolol, which decreases fluid production in the eye.
How is it different from using each drug separately?
The combination provides a convenient single-drop solution for patients who need both drugs, which improves adherence and simplifies treatment. It also reduces the overall preservative exposure to the eye, which can be beneficial for long-term therapy.
What are common side effects?
Side effects can include mild burning, eye redness, or a sensation of something in the eye. Systemic effects such as bradycardia, fatigue, or shortness of breath may occur due to timolol absorption, particularly in sensitive individuals.
Can it be used in people with asthma?
It is generally not recommended for people with asthma or severe respiratory diseases, as timolol can cause bronchospasm. An alternative therapy without a beta-blocker should be considered in such cases.
How often is this medication applied?
This medication is usually administered once daily in the evening, which aligns with the peak activity of latanoprost. Maintaining consistent use is crucial to achieving the desired reduction in eye pressure.
Can I use these drops with my contact lenses?
Remove soft contact lenses before instilling the drops because preservatives can be absorbed by the lens material. After dosing, wait the time specified in the product leaflet before reinserting lenses. This helps avoid irritation and ensures the full dose reaches the eye surface. If you have significant dry eye or lens discomfort, ask your clinician about preservative-free options or adjusting lens wear while on therapy.
What side effects should I watch for early on?
Common effects include mild burning or stinging on instillation, red eyes, and brief blurred vision. Eyelash growth and eyelid or iris color changes may occur with prostaglandin analogs. Because timolol is a beta blocker, some people notice fatigue or a slower pulse. Seek care urgently for severe breathing difficulty, chest pain, swelling of the face or throat, or sudden vision changes.
How should I time other eye medications with this therapy?
If you use more than one eye medication, separate administrations by at least five minutes so the first drop is not washed out by the second. Ointments generally go on last. Using punctal occlusion for one to two minutes after each drop can reduce systemic exposure. Follow your clinician’s instructions and the package insert for the sequence that fits your regimen.
Will iris or eyelash changes reverse if I stop?
Iris darkening from prostaglandin analogs may be permanent. Eyelash growth and eyelid skin changes often lessen after stopping, but the timing varies. If cosmetic changes are a concern, discuss risks and benefits before starting. Your clinician can review whether a different class might meet your treatment goals with a lower chance of these effects.
What if I miss a dose or dose twice by mistake?
If you miss a dose, use the next dose at the usual time. Do not double doses. If you accidentally used two doses close together, simply resume the normal schedule. Using more than directed will not improve results and may increase side effects. Keep a dosing reminder to help maintain consistent nightly use.
Are there medical conditions that make this product unsuitable?
People with asthma, severe COPD, slow heart rate, heart block, or certain heart failure should review risks of ocular beta blockers with their prescriber. Those with active eye infection, herpetic keratitis, or recent surgery need individualized guidance. Discuss all conditions and medicines so your clinician can decide if this treatment fits your situation.
How long until my eye pressure is reassessed?
Your care team typically checks intraocular pressure after starting a new therapy, then at intervals based on your risk and response. Many patients are seen within weeks to months, but schedules vary. Keeping follow-up visits and using drops consistently are key to assessing whether the chosen regimen meets your target pressures.
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