Cambia® Oral Solution for Migraine

Cambia® PD Oral Solution is a prescription powder that you mix with water for the acute treatment of migraine attacks in adults. It helps reduce migraine pain and common associated symptoms when taken at the first sign of an attack. This page explains how it works, who it’s for, and how you can order it for care that Ships from Canada to US, including options for those paying without insurance.

What Cambia Is and How It Works

Cambia® contains diclofenac potassium, a nonsteroidal anti-inflammatory drug. It works by inhibiting cyclooxygenase enzymes, which lowers prostaglandin production involved in pain and inflammation. This mechanism can ease migraine pain as well as sensitivity to light and sound, and nausea in some patients.

Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

The formulation comes as diclofenac potassium oral solution packets that you dissolve in water right before use. Because it is taken as a liquid, absorption may be quicker than some solid oral forms. This medicine is approved for the acute treatment of migraine with or without aura in adults and is not indicated for prevention.

For broader learning on the condition, see our overview of Migraine and explore patient-friendly insights like Migraine In Children and Menstruation And Migraines.

Who It’s For

This treatment is for adults diagnosed with migraine who need an as-needed option for acute attacks. It is not for preventive use, tension-type headaches, or cluster headaches. People with a history of allergic reactions to NSAIDs, aspirin-sensitive asthma, active gastrointestinal bleeding, or recent coronary artery bypass graft surgery should avoid it. Those with cardiovascular disease, hypertension, kidney or liver problems, or ulcer history should discuss risks with a healthcare professional.

Learn more about pain-related options in our Pain Inflammation category.

Dosage and Usage

Use at the first sign of a migraine. Open one packet and dissolve the entire contents in a small amount of water as directed on the label. Stir to fully disperse the powder and drink the mixture right away. Taking it on an empty stomach may support faster uptake.

The labeled adult dose corresponds to diclofenac potassium oral solution 50 mg given once for a single attack. Do not take a second dose within 24 hours. If your migraine returns or you need frequent treatment days, speak with your prescriber about your plan.

General administration tips:

• Prepare the solution only when you are ready to take it.
• Do not split packets; take the full prepared dose exactly as labeled.
• Avoid exceeding recommended use to lower the risk of medication overuse headache.
• If nausea is present, sip slowly after mixing to help tolerance.

When uncertain, follow the official Patient Information and your clinician’s instructions.

Strengths and Forms

This medicine is supplied as single-dose packets of powder for oral solution. In most markets, the strength is 50 mg per packet. Availability and pack sizes may vary.

Some patients ask about brand versus generic. Your prescriber and pharmacist can advise on appropriate substitutions, but availability differs by region and over time. Packets are designed for quick preparation and use at migraine onset.

If you are comparing products, note we list origin details in Canada attributes where available.

Missed Dose and Timing

This therapy is used as needed at the start of a migraine attack, so there is no daily schedule. If you planned to take it but the headache subsided, do not take it later. If a migraine returns the same day, do not repeat the dose. For recurring attacks on many days, discuss adjustments with your prescriber.

Storage and Travel Basics

Keep packets at room temperature in a dry place, away from excess heat and moisture. Store in the original carton to protect the sachets. Keep out of reach of children and pets.

For travel, carry packets and your prescription label in your hand luggage. Keep them sealed until use. When flying, pack a copy of your prescription in case of screening questions. During trips, place packets in a small protective pouch to avoid crushing. Do not mix in advance; prepare only at the time of dosing.

Benefits

As part of the NSAID class, this therapy may ease headache pain and reduce migraine-associated symptoms like light sensitivity and nausea. The single-dose packet format can be convenient to keep on hand and mix quickly. A liquid dose may suit those who struggle to swallow tablets during an attack. Many appreciate that it is taken only when needed.

Side Effects and Safety

• Stomach pain or upset
• Nausea or vomiting
• Dyspepsia or heartburn
• Dizziness or headache
• Diarrhea or constipation
• Skin rash or itching

Serious but less common risks include gastrointestinal bleeding or ulcer, cardiovascular events (such as heart attack or stroke), elevations in blood pressure, kidney problems, liver issues, severe skin reactions, or serious allergic reactions including anaphylaxis. Stop the medicine and seek urgent care if you experience chest pain, shortness of breath, weakness on one side of the body, black or bloody stools, vomiting blood, facial swelling, or difficulty breathing. Using the lowest effective amount on the fewest days needed may reduce risk.

Drug Interactions and Cautions

High-level interactions can occur with:

• Blood thinners and antiplatelets (for example, warfarin, clopidogrel)
• SSRIs and SNRIs, which may increase bleeding risk
• ACE inhibitors, ARBs, and diuretics
• Lithium or methotrexate
• Cyclosporine or tacrolimus
• Other NSAIDs, aspirin, or systemic steroids
• Alcohol, which can raise gastrointestinal risk

Use during late pregnancy is not recommended. Avoid right before or after coronary artery bypass graft surgery. People with a history of peptic ulcer disease, significant cardiovascular conditions, kidney or liver impairment, or asthma with NSAID sensitivity need individualized guidance.

What to Expect Over Time

Relief varies by person and by how early the dose is taken. Some people experience improvement in pain intensity and associated symptoms when the treatment is used at the first sign of migraine. Track your use and effects in a simple log to share with your healthcare professional. If your attacks change, become more frequent, or are not relieved, your prescriber may adjust your overall migraine plan, which can include preventive options.

Compare With Alternatives

For many adults, triptans remain a first-line option for acute attacks. If your clinician recommends a triptan, you can review Zolmitriptan. For prevention between attacks, beta blockers are commonly used; see Propranolol for a prescriber-directed option. Your clinician will help tailor choices to your medical history.

Pricing and Access

We list transparent options so you can review the Cambia oral solution price before checkout. Many self-pay users compare the Cambia cash price with local pharmacy quotes and choose what best fits their budget. This service offers US shipping from Canada to help U.S. patients access medication through licensed partners. If you are looking for current savings, check our Promotions page for occasional offers.

All orders use an encrypted checkout. Your valid prescription is required and verified before dispensing.

Availability and Substitutions

Supply can vary by market and by pack size. If a specific packet count is unavailable, your prescriber may recommend a different pack size or an alternative acute therapy. NSAID-based and triptan options are the most common substitutes, depending on your clinical profile.

Patient Suitability and Cost-Saving Tips

This medicine may suit adults who need an as-needed non-opioid option for acute migraine attacks, especially those who prefer a liquid dose. It may not be appropriate for people with significant cardiovascular disease, prior gastrointestinal bleeding, severe kidney or liver issues, or NSAID allergy.

Cost-saving ideas:

• Ask your prescriber about a multi-pack quantity to reduce per-dose costs.
• Set refill reminders so you have packets on hand before travel.
• Compare Canadian cash-pay options with local pharmacy quotes.
• Use your clinic’s e-prescribing to reduce delays and errors.
• Store unused packets properly so none are wasted.

Questions to Ask Your Clinician

• Is this NSAID appropriate given my heart, stomach, kidney, or liver history?
• How should I time the dose relative to symptom onset or food?
• What warning signs mean I should stop and seek care?
• How many treatment days per month are safe for me?
• Could a preventive option reduce how often I need acute therapy?
• How does this compare with triptans or other NSAIDs for my profile?

Authoritative Sources

FDA DailyMed: Cambia (Label Search)

Assertio Therapeutics: Products

Health Canada: Drug Product Database

Ready to get started? You can purchase Cambia online today for US delivery from Canada with prompt, express shipping. Always use exactly as prescribed. This information is educational and not a substitute for your clinician’s advice.