Faslodex® Injection for HR+ Breast Cancer

Fulvestrant is an estrogen receptor antagonist used for hormone receptor–positive advanced breast cancer. It is administered by a healthcare professional in a clinic setting. Ships from Canada to US options at BorderFreeHealth can help you manage treatment costs, even without insurance.

What Faslodex® Is and How It Works

This therapy belongs to a class known as selective estrogen receptor degraders. It binds to the estrogen receptor and accelerates its breakdown, which can slow or stop growth of estrogen-driven tumors. Many patients receive fulvestrant injection after progression on prior endocrine therapy. For background on uses and safety, see our guide Fulvestrant Injection Uses.

Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

This medicine may be used alone or alongside certain targeted agents, based on your oncologist’s plan. You can also explore our Cancer category for additional therapies.

Who It’s For

This treatment is indicated for adults with hormone receptor–positive, HER2‑negative advanced or metastatic breast cancer. It may be used after progression on antiestrogen therapy, or in combination with specific targeted medicines as directed by your prescriber. Learn more about the condition in our Breast Cancer hub and related reading like Ibrance Palbociclib and What Is Anastrozole.

People who are pregnant or may become pregnant should not receive this therapy. Use effective contraception during treatment and for a time after the last dose as advised on the official label. Tell your clinician about liver disease, bleeding disorders, low platelets, allergies, or any injection-site problems.

Dosage and Usage

Administration occurs in a clinic by intramuscular injection, typically into the buttock muscles. The labeled schedule uses an initial dosing phase, followed by once‑monthly maintenance. Your healthcare professional will prepare the syringes, warm to room temperature per label, and inject slowly using the recommended technique.

Arrive on time for each appointment and report any injection-site pain, redness, or swelling. If you are prescribed combination therapy, your team will coordinate visit timing with the other medicine. Do not attempt to inject this treatment at home.

Strengths and Forms

This medicine is supplied as prefilled syringes for intramuscular use. Commonly, a single-dose syringe contains 250 mg in 5 mL; availability can vary by manufacturer. Some patients may receive a brand product, while others may receive a generic alternative such as sandoz fulvestrant, depending on pharmacy supply.

Specific pack sizes and presentations may differ. Your dispensing pharmacy will provide the product that matches your prescription and local availability.

Missed Dose and Timing

If you miss an appointment, contact your clinic to reschedule as soon as possible. Do not double up doses. Your care team will decide how to adjust the schedule so you can continue safely.

Storage and Travel Basics

Clinics typically handle storage. If you ever need to transport the product to a clinic, keep it refrigerated as directed on the label, protect from light, and do not freeze or shake. Keep all medicines out of reach of children and pets. When traveling, carry documentation of your prescription and appointment details. Use insulated carriers only if your clinic instructs you to do so, and avoid placing syringes in checked luggage. We use temperature-controlled handling when required.

Benefits

This estrogen receptor–targeting therapy can help slow tumor growth driven by estrogen signaling. It is given by trained staff, so you do not need to self-inject at home. The maintenance schedule is typically monthly after the initial phase, which can simplify planning. It can be used alone or paired with compatible targeted therapies when appropriate.

Side Effects and Safety

• Injection-site pain or swelling
• Nausea or vomiting
• Fatigue or weakness
• Headache
• Hot flashes
• Back or bone pain
• Elevated liver enzymes

Serious but less common risks can include hypersensitivity reactions, sciatica or neuralgia related to injection, bleeding events in those with clotting issues, and liver problems. Contact your clinician if you notice severe pain, signs of allergic reaction, yellowing of the skin or eyes, or unusual bleeding or bruising. For additional reading on managing endocrine therapy effects, see Exemestane Side Effects.

Drug Interactions and Cautions

Tell your prescriber about all medicines, vitamins, and herbals. While this treatment has limited major drug–drug interactions, your team will review anticoagulants, antiplatelets, or supplements that affect bleeding risk. Discuss liver conditions, injection-site concerns, and pregnancy planning. Do not start or stop therapies without checking with your oncology team.

What to Expect Over Time

Your healthcare professional will monitor symptoms, labs, and imaging at regular intervals. Some people notice gradual changes in pain, energy, or other cancer‑related symptoms as treatment continues. Response varies by individual and by prior therapies. Staying on schedule, reporting side effects early, and keeping follow‑up visits give your team the best information to guide care.

Compare With Alternatives

Several other approved therapies may be used in HR‑positive, HER2‑negative advanced disease, sometimes alongside an estrogen receptor degrader. CDK4/6 inhibitors are common partners. Two options available on our site include Verzenio and Kisqali. Your oncologist will decide if and when a combination is appropriate.

Pricing and Access

We offer transparent options so you can review the fulvestrant injection price before you proceed. Many patients explore fulvestrant Canadian pricing to compare their out‑of‑pocket costs. You can browse our Canada category for supply sources. We provide US shipping from Canada, and you will see product details and current availability at checkout. Your prescription is required for dispensing.

For education on aromatase inhibitors used in related settings, you can also review Anastrozole and our product Aromasin pages.

Availability and Substitutions

Supply can vary by manufacturer and package size. If your prescribed brand is unavailable, your prescriber may recommend a suitable alternative. Our team will let you know if the fulvestrant injection ships to US from a different partner pharmacy than usual. We do not guarantee restock dates; your clinician may suggest another agent if needed.

Patient Suitability and Cost-Saving Tips

Candidates typically have HR‑positive, HER2‑negative advanced or metastatic disease and can receive intramuscular injections in a clinic. It is not appropriate during pregnancy. People with liver impairment, bleeding disorders, or severe injection‑site issues need careful evaluation. To manage budgets, discuss scheduling that aligns visits and imaging. Ask whether multi‑cycle planning helps reduce clinic trips. Consider using reminders for appointment timing. Patients sometimes track the fulvestrant cash price over time to plan refills and follow‑up around the same date each month.

Questions to Ask Your Clinician

• Therapy goals: disease control vs. symptom relief
• Best partner drugs and sequence of care
• Monitoring plan and imaging intervals
• Managing injection-site discomfort
• Liver function checks and lab schedule
• Fertility, contraception, and pregnancy precautions
• When to call about side effects

Authoritative Sources

Review official information from these sources:

• FDA Prescribing Information
• DailyMed Label
• Health Canada DPD

Ready to take the next step? You can order fulvestrant online through BorderFreeHealth with prompt, express shipping. Always follow your prescriber’s guidance; this page does not replace professional medical advice.