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Glimepiride

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Uses of Glimepiride

Glimepiride is commonly used to help lower blood sugar levels in people with type 2 diabetes.

Glimepiride helps to increase your body’s insulin levels. Insulin is released from your pancreas. It is a hormone that helps your body use blood sugar (glucose) as a source of energy.

Precautions and Warnings

People who are allergic to any of the following should not use glimepiride.

  • Glimepiride
  • Amaryl
  • Any other medicine containing glimepiride
  • Any other medicine known as a sulfonamide
  • Any of the ingredients in the specific product dispensed

Your pharmacist can tell you all of the ingredients in the specific glimepiride products they stock.

Glimepiride is not used to treat type 1 diabetes. Glimepiride is not used to treat diabetic ketoacidosis.

ertain conditions that cause increased stress on your body, like fever, trauma (such as a car accident), infection, or surgery can change the amount of diabetes medicines you need to take to control your diabetes. Talk to your healthcare provider if you have any of these conditions to decide if your medicine needs to be changed.

Talk to your healthcare provider about how to prevent, recognize, and manage low blood sugar (hypoglycemia), high blood sugar (hyperglycemia), and diabetes-related problems.

People who are 65 years or older can be at greater risk for some side effects from glimepiride. Talk to your healthcare provider about your risks if you are in this age group.

Glimepiride can affect your alertness or coordination, especially if your blood sugar drops too low. Do not drive or do other activities that require alertness or coordination until you know how glimepiride affects you.

Glimepiride can make your skin more sensitive to light from the sun, sunlamps, and tanning beds. This is called photosensitivity. Exposure to this light can cause severe sunburns, blisters, and swelling. If you need to be in sunlight, wear sunscreen, a hat, and clothing that covers your skin.

It is not known if or how glimepiride could affect pregnancy or harm an unborn baby. Tell your healthcare provider if you are or plan to become pregnant. Your healthcare provider will advise you if you should take glimepiride while you are pregnant or trying to get pregnant.

It is not known if glimepiride passes into breast milk. Tell your healthcare provider if you are breastfeeding or plan to breastfeed. Your healthcare provider will advise you if you should take glimepiride while breastfeeding.

Dosage

Glimepiride comes as a tablet to take by mouth. It is usually taken once a day with breakfast or the first main meal of the day. To help you remember to take glimepiride, take it at around the same time every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take glimepiride exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Your doctor will probably start you on a low dose of glimepiride and gradually increase your dose if needed. After you have taken glimepiride for some time, glimepiride may not control your blood sugar as well as it did at the beginning of your treatment. Your doctor may adjust the dose of your medication as needed so that the medication will work best for you. Be sure to tell your doctor how you are feeling and if your blood sugar test results have been higher or lower than normal at any time during your treatment.

Glimepiride helps control blood sugar but does not cure diabetes. Continue to take glimepiride even if you feel well. Do not stop taking glimepiride without talking to your doctor.

Side Effects

Common side effects:

  • Low blood sugar (see below)
  • Headache
  • Nausea
  • Dizziness

Serious side effects:

  • Breathing problems or wheezing
  • Racing heart
  • Fever or general ill feeling
  • Swollen lymph nodes
  • Swelling of the face, lips, mouth, tongue, or throat
  • Trouble swallowing or throat tightness
  • Itching, skin rash, or pale red bumps on the skin called hives
  • Nausea or vomiting
  • Dizziness, feeling lightheaded, or fainting
  • Stomach cramps
  • Joint pain

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