Isopto Carpine

Uses of Isopto Carpine

Isopto Carpine ophthalmic solution is used to control intraocular pressure in chronic simple glaucoma. In acute glaucoma it may be used alone prior to emergency surgery, or in combination with other miotics or carbonic anhydrase inhibitors. Patients can be maintained on Isopto Carpine ophthalmic solution as long as intraocular tension is controlled and there is no visual deterioration as indicated by changes in the visual field.

Precautions and Warnings

Retinal detachment has been reported when miotics are used in susceptible individuals, such as Young patients with myopia or patients with history of retinal detachment. Fundus examination is advised prior to initiation of treatment with Isopto Carpine ophthalmic solution.

Miotics should be avoided in acute inflammatory diseases of the anterior chamber.

A paradoxical rise in intraocular pressure may be observed in patients with severely compromised trabecular outflow.

Caution is advised in the presence of corneal or conjunctival damage to avoid excessive penetration which can produce systemic toxicity.

Isopto Carpine ophthalmic solution should be used with caution in patients with acute cardiac failure, bronchial asthma, peptic ulcer, hyperthyroidism, gastro-intestinal spasm, Parkinson’s disease, urinary tract obstruction, recent myocardial infarction, hypertension and hypotension due to the risk of exacerbating these conditions.

Contact dermatitis may develop after prolonged use.

Isopto Carpine ophthalmic solution contains benzalkonium chloride which may cause eye irritation and is known to discolour soft contact lenses. Avoid contact with soft contact lenses. Patients must be instructed to remove contact lenses prior to the application of Isopto Carpine and wait at least 15 minute before reinsertion.

Isopto Carpine ophthalmic solution is not recommended during pregnancy

Dosage

2 drops topically in the eye(s) 3 times daily or as directed by a physician

Side Effects

Common side effects:

• headache/browache,
• accommodative change,
• eye irritation,
• eye pain,
• blurred vision,
• visual impairment.