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Komboglyze is a combination diabetes medication containing saxagliptin and metformin, used to improve blood sugar control in type 2 diabetes patients.
Benefits
- Combines two medications for better glucose control.
- It helps lower HbA1c levels effectively.
- It can be used alongside diet and exercise for optimal diabetes management.
Dosage
- Typically, one tablet twice daily with meals.
- Dose adjustments based on renal function and individual response.
Warnings and Precautions
- It is not recommended for individuals with severe kidney disease.
- It may cause lactic acidosis in rare cases.
- Regular kidney function tests are advised.
Usage Instructions
- Take with food to reduce gastrointestinal side effects.
- Do not split or crush the tablets.
- Maintain a consistent medication schedule.
Storage Information
- Store at room temperature away from moisture.
Common Side Effects
- Nausea, diarrhea, headache, and upper respiratory infections.
- Serious effects include pancreatitis—seek medical help if severe abdominal pain occurs.
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What is Komboglyze used for?
Komboglyze is primarily used to help manage blood sugar levels in adults with type 2 diabetes. It is often prescribed alongside diet and exercise to improve glycemic control when other medications have not been sufficient. This combination therapy aims to reduce the risk of diabetes-related complications over time.
How does Komboglyze work?
Komboglyze combines two active ingredients: saxagliptin and metformin. Saxagliptin increases the body’s natural production of insulin after meals, while metformin decreases glucose production in the liver and improves the body’s sensitivity to insulin. Together, they offer a comprehensive approach to managing type 2 diabetes.
Can Komboglyze cause side effects?
Yes, Komboglyze can cause side effects, although not everyone experiences them. Common side effects include headaches, upper respiratory tract infections, and gastrointestinal discomfort. Rare but serious side effects include lactic acidosis, especially in those with kidney issues or excessive alcohol use.
Should Komboglyze be taken with food?
Yes, it is recommended to take Komboglyze with meals. Taking it with food helps minimize gastrointestinal side effects, such as nausea and diarrhea, which are more common with metformin.
Is Komboglyze safe for people with kidney problems?
Caution is advised when prescribing Komboglyze to individuals with kidney impairment. Kidney function should be assessed before starting treatment and monitored regularly, as dosage adjustments may be necessary to reduce the risk of lactic acidosis.
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