Nexavar® Tablets for Liver, Kidney, and Thyroid Cancer

Nexavar is a prescription cancer medicine for certain liver, kidney, and thyroid cancers. This page explains how it works, safety basics, and ways to access Nexavar tablets without insurance, with US delivery from Canada.

What Nexavar Is and How It Works

Nexavar® contains sorafenib, a multi-kinase inhibitor. It targets pathways that help tumors grow and form new blood vessels, including RAF kinases and vascular growth factor receptors. By blocking these targets, the treatment may slow tumor cell proliferation and reduce angiogenesis. Sorafenib 200 mg tablets are taken by mouth and used under a prescriber’s supervision for approved indications. Borderfreehealth connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

This medicine is approved for unresectable hepatocellular carcinoma, advanced renal cell carcinoma, and certain differentiated thyroid cancers that no longer respond to radioactive iodine. See the official prescribing information for full details on uses and safety.

Explore more related options and conditions in our Cancer category.

Who It’s For

This therapy is used in adults with unresectable liver cancer, advanced kidney cancer, or differentiated thyroid cancer that has progressed after radioactive iodine. A clinician will confirm diagnosis and eligibility before prescribing. Learn more about these conditions here: Liver Cancer, Kidney Cancer, and Thyroid Cancer.

Nexavar brand sorafenib tablets are not for everyone. People with severe allergies to ingredients should avoid it. Use caution with heart disease, uncontrolled hypertension, recent bleeding, or planned surgery. This medicine can harm an unborn baby. Effective contraception is recommended during treatment and for a period after the last dose. Breastfeeding is not advised during therapy.

Dosage and Usage

Follow the directions on the official label and the prescriber’s instructions. The usual starting schedule is two tablets twice daily. Take it without food, at least one hour before or two hours after a meal. Swallow tablets whole with water. Try to take doses about 12 hours apart.

If side effects occur, a prescriber may adjust the schedule or pause therapy. Do not change dosing on your own. Regular monitoring, including blood pressure and lab tests, is commonly recommended during therapy.

Strengths and Forms

This product is supplied as film‑coated oral tablets. A commonly available strength is 200 mg. Availability can vary by partner pharmacy and country of origin, and generics may be offered when permitted.

Missed Dose and Timing

If a dose is missed and it is close to the next scheduled time, skip the missed dose. Do not double up. If it is not close to the next dose, take it as soon as remembered and resume the regular schedule. For refills, you can place a Nexavar refill online to avoid gaps in therapy once a prescriber authorizes continued treatment.

Storage and Travel Basics

Store tablets at room temperature in the original container with the lid closed. Protect from moisture and light. Keep out of reach of children and pets. When traveling, carry the medicine in a hand luggage compartment along with a copy of the prescription and medication list. Security officers may ask for original labeling and documentation. Partner pharmacies use temperature-controlled handling when required.

Benefits

This targeted therapy can inhibit signals that promote tumor growth and blood vessel formation. Oral dosing avoids clinic infusion visits and may fit more easily into daily routines. Treatment can be coordinated across oncology care teams, with regular assessments guiding ongoing use.

Side Effects and Safety

• Common effects: diarrhea, fatigue, decreased appetite, weight loss, nausea
• Skin and nails: rash, hand‑foot skin reaction, dryness, hair thinning
• Cardiovascular: high blood pressure may occur
• Labs: changes in liver tests can appear

Serious risks can include severe bleeding, heart problems, liver injury, gastrointestinal perforation, wound‑healing issues, and rare brain swelling conditions. Report chest pain, severe headache, fainting, yellowing of skin or eyes, or unusual bleeding. This medicine may affect fertility. Before any surgery or dental procedure, inform the care team, as the treatment may need to be held. For complete risks, consult the official labeling.

Drug Interactions and Cautions

Sorafenib is affected by certain drugs that alter liver enzymes. Strong inducers such as rifampin and some anticonvulsants may reduce effectiveness. Herbal products like St. John’s wort can interact. Certain antibiotics, antifungals, and antivirals may require added caution. Warfarin and other anticoagulants can increase bleeding risk and may need closer monitoring. High‑fat meals can reduce exposure; take as directed on an empty stomach. Avoid starting or stopping other medicines and supplements unless cleared by a prescriber.

What to Expect Over Time

Some effects like skin reactions or diarrhea may appear early and can often be managed with supportive care. Blood pressure and labs are usually checked regularly. Response assessments are scheduled by the oncology team. If therapy is tolerated and the disease remains controlled, clinicians may continue treatment while monitoring for side effects. Adherence to the empty‑stomach schedule helps keep levels stable.

To learn more about kinase inhibitors used in oncology, see our article Cabometyx Treatment Benefits.

Compare With Alternatives

Other approved oral kinase inhibitors may be considered based on cancer type and prior therapy. For advanced kidney or liver cancers, options include Cabometyx and Stivarga. Each medicine has specific indications, dosing, and safety profiles. Discuss choices with an oncology clinician and consult the official labels. For background reading, see Cabometyx Treatment Benefits.

Pricing and Access

We list Canadian pharmacy options with US shipping from Canada after a valid prescription is received. You can check current pricing, upload a prescription, and track orders from your account. For savings, compare generic offers when available and consider multi‑month fills when appropriate.

Many patients compare Nexavar cost comparison Canada when reviewing options. Those paying cash may also look for Sorafenib cash price to plan monthly therapy budgets. See available promotions on our Promotions page when applicable. We cannot quote dollar amounts here; see the product page for live details and fulfillment options.

Availability and Substitutions

Supply can vary by partner pharmacy. Sorafenib ships to US from licensed Canadian sources after verification. If a specific brand pack is unavailable, a prescriber may recommend a suitable alternative or a generic equivalent when appropriate. We do not provide restock dates; check the product page for current status.

Patient Suitability and Cost-Saving Tips

Candidates include adults with the labeled cancer types whose clinicians deem therapy appropriate. Those with significant cardiac disease, recent major bleeding, or impending surgery may require special planning. Contraception recommendations apply to patients who can become pregnant, and breastfeeding should be avoided during treatment.

To help manage costs, consider multi‑month supplies when appropriate and permitted. Set reminders to request refills several days ahead. If switching between brand and generic is allowed by the prescriber, compare options and review differences in non‑active ingredients. Use your secure account to upload prescriptions, review order history, and manage addresses for streamlined delivery.

Questions to Ask Your Clinician

• Goals of therapy: what outcomes are being monitored
• Monitoring plan: labs, blood pressure, and imaging schedule
• Managing effects: steps for skin reactions, diarrhea, or nausea
• Drug interactions: medicines, supplements, or foods to avoid
• Surgery plans: how long to pause before and after procedures
• Fertility and pregnancy: contraception timelines and counseling
• Access: whether brand or generic is suitable for the treatment plan

Authoritative Sources

• FDA DailyMed Label
• Manufacturer Information
• Health Canada DPD

Start at Borderfreehealth for prompt, express shipping. Ships from Canada to US. This content is not medical advice; consult the official label and a licensed clinician.