Nexavar

Nexavar is an oral targeted therapy used to treat certain types of advanced cancers, including liver cancer (hepatocellular carcinoma), kidney cancer (advanced renal cell carcinoma), and thyroid cancer. It works by blocking multiple proteins that cancer cells need to grow and form blood vessels, helping to slow the spread of the disease.

Benefits

• Slows tumor growth in advanced liver, kidney, and thyroid cancers.
• Blocks cancer cell division and blood vessel formation in tumors.
• Offers a treatment option for patients who are not eligible for surgery or have failed other therapies.
• Oral medication taken at home, avoiding the need for injections or infusions.
• Used worldwide as a standard treatment for advanced liver cancer.

Dosage

• The usual adult dose is 400 mg twice daily (two 200 mg tablets in the morning and two in the evening).
• Should be taken on an empty stomach — at least 1 hour before or 2 hours after a meal.
• Tablets must be swallowed whole with water.
• Your doctor may adjust the dose depending on how well you tolerate the treatment.

Warnings and Precautions

• May cause high blood pressure — monitor regularly.
• Can lead to heart problems, including chest pain or heart attack.
• Risk of bleeding — inform your doctor if you have a history of bleeding issues.
• Can affect liver function — regular blood tests are needed.
• Not recommended during pregnancy or breastfeeding.
• Use with caution in patients with heart disease, liver problems, or recent surgery.

Usage Instructions

• Take twice daily, on an empty stomach.
• Keep a consistent schedule, spacing doses about 12 hours apart.
• Swallow tablets whole with a glass of water.
• Do not take missed doses close to the next scheduled dose. Skip it instead.
• Continue treatment as prescribed, unless advised to stop by your doctor.

Storage Information

• Store at room temperature (20°C to 25°C).
• Keep the medicine in its original packaging.
• Protect from moisture and light.
• Keep out of reach of children and pets.

Common Side Effects

• Mild to moderate effects: tiredness, diarrhea, rash, hand-foot skin reactions, hair thinning, weight loss, or high blood pressure.
• Serious (seek medical attention): chest pain, severe bleeding, yellowing of the skin or eyes, signs of liver or heart problems, or severe skin reactions.