Palladia® Tablets for Dogs

Palladia® is a veterinary cancer medicine used for canine mast cell tumors. It is an oral targeted therapy that blocks specific signals that help tumors grow. This page explains how the treatment works, who it may suit, and how to handle it safely, with practical tips on access and storage. Ships from Canada to US, helping many pet families explore options without insurance.

What Palladia Is and How It Works

This medicine contains toceranib phosphate, a tyrosine kinase inhibitor for dogs. It targets receptors involved in tumor cell growth, survival, and blood supply. By inhibiting these pathways, the treatment may reduce tumor size or slow progression in eligible cases. As a prescription-only therapy, decisions about starting or continuing should be guided by a veterinarian.

Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

Some pets receive Mast Cell Tumors care that combines surgery, local therapy, and systemic agents. The role of targeted therapy is determined by tumor grade, location, margins, and staging. Learn more background in our article Palladia For Dogs.

As labeled, toceranib tablets for dogs are administered under veterinary supervision with ongoing monitoring. Bloodwork and urinalysis checks help manage safety, especially during the first months.

Who It’s For

This treatment is used in dogs with mast cell tumors diagnosed by a veterinarian. It may be considered for nonresectable or recurrent disease, or when systemic therapy is appropriate after local therapy. Suitability depends on staging, concurrent conditions, prior treatments, and the pet’s overall health.

Dogs with uncontrolled gastrointestinal ulceration, severe bleeding disorders, or significant organ dysfunction may not be candidates. Breeding, pregnant, or lactating animals should not receive it. People who are pregnant or breastfeeding should avoid handling this medicine, including contaminated waste.

Dosage and Usage

Veterinarians typically prescribe dosing on an every-other-day schedule. Exact milligram strength and total dose are calculated by body weight and clinical response. Do not change the schedule without veterinary guidance. The tablets should be swallowed whole with water; do not split or crush.

Dosing often begins with label-based schedules and is adjusted based on tolerance and response. Many clinics advise consistent timing and careful observation for appetite, stool changes, and energy. The phrase toceranib 10mg may appear on packaging, but the actual daily amount is determined by weight, not by a single tablet strength.

To reduce household exposure, handlers should wear disposable gloves when administering. Wash hands after handling the bottle or any waste. Keep dosing logs to support veterinary follow-up and lab monitoring.

Strengths and Forms

Film-coated oral tablets are available in multiple strengths. Common presentations include Palladia 50 mg tablets. Availability may vary by pharmacy partner, and the exact pack sizes offered can change over time.

Tablets are designed to limit direct contact with the active ingredient. Because of exposure risks, broken or moistened tablets should not be handled barehanded. Ask the clinic about safe handling and disposal protocols.

Missed Dose and Timing

If a dose is missed, general label guidance is to give the next scheduled dose and avoid doubling. When uncertain, contact the prescribing clinic. Keep to a consistent every-other-day rhythm whenever possible. If vomiting occurs shortly after a dose, veterinarians typically advise contacting the clinic for case-specific guidance rather than repeating a dose without direction.

Storage and Travel Basics

Store at room temperature in a secure, dry location away from children and other animals. Keep the bottle closed tightly and in the original labeled container. Do not store in humid environments where tablets could degrade. Avoid handling broken tablets; if breakage occurs, use gloves and follow local hazardous waste guidance.

During travel, keep the prescription label with the bottle. Pack tablets in a crush-resistant container within carry-on luggage when possible. Use a separate, sealable plastic bag to reduce exposure risks. For longer trips, bring dosing logs and clinic contact details. Dispose of used gloves safely, and wash hands after any contact with excreta while the pet is on treatment.

Benefits

This targeted therapy class may shrink tumors or stabilize disease in certain dogs, based on clinical assessment. Oral dosing at home can reduce hospital visits when a veterinarian judges it appropriate. The treatment can sometimes be paused or adjusted if side effects occur, supporting individualized care plans. Coordination with surgery or local treatments may improve overall management in selected cases.

For some families, oral cancer therapy at home offers scheduling flexibility and structured monitoring. Discuss goals of care, quality of life metrics, and realistic expectations with the clinical team. When used alongside supportive care, tolerability may improve.

Some dogs start on Palladia tablets for dogs after recovery from surgery; others use it when surgery is not feasible. Every plan depends on pathology, staging, and the pet’s condition.

Side Effects and Safety

• Gastrointestinal upset: vomiting, diarrhea, decreased appetite
• Lethargy or decreased activity
• Weight loss
• Lameness or musculoskeletal discomfort
• Black stools or signs of gastrointestinal bleeding
• Skin changes around tumor sites

Serious effects can include gastrointestinal perforation, severe bleeding, significant dehydration, high blood pressure, kidney or liver changes, and low blood counts. Early reporting of concerning signs is important. People should handle the tablets and pet waste with care. Pregnant or breastfeeding people should not handle this medicine or contaminated items. The prescribing veterinarian may recommend baseline and periodic lab testing to help manage safety.

Drug Interactions and Cautions

Toceranib may interact with drugs that affect similar pathways or increase gastrointestinal risk. Caution is warranted with certain NSAIDs and steroids due to ulceration risk. Some antifungals, antibiotics, and other agents can alter metabolism; the clinic will review the pet’s full medication list. If infections arise during therapy, options such as Cephalexin may be considered when appropriate, but only under veterinary direction.

Herbal supplements and over-the-counter products should be disclosed to the prescriber. The veterinarian will tailor therapy if significant interactions are likely.

What to Expect Over Time

Many dogs are monitored closely during the first weeks for gastrointestinal tolerability and hydration. Tumor response varies by case and can include measurable shrinkage or disease stabilization. Regular rechecks allow dose adjustments or temporary interruptions if needed. Quality of life measures, appetite trends, and stool consistency help guide decisions. Some dogs remain on therapy for extended periods when benefits persist and safety is maintained.

Lab work intervals are set by the clinician and may be adjusted based on findings. Owners often keep notes and share photos of tumor sites to document changes between visits.

Compare With Alternatives

Veterinarians may consider additional options depending on tumor grade, stage, and surgical margins. Alternatives can include other targeted agents such as masitinib, or cytotoxic chemotherapy protocols like lomustine, when appropriate. Supportive care often accompanies systemic therapy. For anti-nausea support, clinics may use Cerenia. For pain and inflammation management around procedures, some may consider Onsior Solution in eligible pets.

Choice of therapy depends on pathology, imaging, comorbidities, and caregiver goals. Discuss evidence, monitoring needs, and safety considerations before changes.

Pricing and Access

Borderfreehealth offers Canadian pharmacy access with US shipping from Canada. Check current toceranib price options by selecting the tablet strength on this page. You can view available pack sizes, see updated availability, and proceed through an encrypted checkout. For broad browsing, visit our Pet Medications category. If you are looking for seasonal deals, see current offers on our Promotions page.

For condition background and product context, our category pages and articles can help. Country-of-origin details may be listed under Canada when applicable.

Availability and Substitutions

Supply can vary. If a specific strength or pack size is unavailable, a prescriber may adjust dosing with another strength or recommend an alternative medicine. Pharmacy partners cannot substitute without a new or revised prescription from the veterinarian.

Patient Suitability and Cost-Saving Tips

Candidates often include dogs with confirmed mast cell tumors where systemic therapy is appropriate. Dogs with severe uncontrolled gastrointestinal disease, significant organ impairment, or bleeding risk may not be good candidates. Household considerations matter: safe storage, reliable dosing routines, and the ability to follow handling precautions are important.

To plan ahead, ask the clinic about multi-month supplies when appropriate. Refill reminders can help maintain consistency. Compare options to manage toceranib cost over time, including scheduling rechecks efficiently. For education on related conditions, explore our Mast Cell Tumors page.

Questions to Ask Your Clinician

• Treatment goals: tumor shrinkage, stabilization, or symptom control
• Monitoring plan: visit frequency, lab tests, and imaging
• What side effects need urgent attention and who to contact after hours
• Whether supportive care like anti-nausea or gastroprotectants is recommended
• How other medicines or supplements could interact with therapy
• Plans for dose changes, pauses, or discontinuation if issues arise

Authoritative Sources

• Zoetis Product Information
• FDA CVM Labeling (Palladia)
• Health Canada Drug Product Database

Ready when you are. Complete your order with prompt, express shipping. This information is educational and not a substitute for veterinary advice; follow your veterinarian’s directions and the official label.