Perindopril/Amlodipine Tablets for Hypertension

Perindopril/Amlodipine is a fixed‑dose tablet used to manage high blood pressure. It combines two proven agents to help reduce cardiovascular risk when lifestyle changes and single‑agent therapy are not enough. Ships from Canada to US with options that can work for those paying without insurance.

What Perindopril/Amlodipine Is and How It Works

Perindopril/Amlodipine® pairs an angiotensin‑converting enzyme (ACE) inhibitor with a calcium channel blocker in one once‑daily tablet. The ACE inhibitor reduces angiotensin II formation, which can relax blood vessels and lower resistance. The calcium channel blocker can help arteries stay open by limiting calcium entry into vascular smooth muscle.

Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

Together, the actions may complement each other for blood pressure control. The combination can be useful when a single medicine does not reach target readings or when simplification to one tablet supports adherence. The balance of ACE Inhibitors and a dihydropyridine calcium channel blocker is well studied in hypertension care. In this class, perindopril and amlodipine work on separate pathways, which can reduce the need for dose escalation of either component alone.

Who It’s For

This medicine is indicated for adults with hypertension, including people needing two agents to reach blood pressure goals. It may suit those already stabilized on both components taken separately. Some markets list the combination as perindopril arginine amlodipine, reflecting the salt form of perindopril used in certain regions.

It is not for use during pregnancy. People with a history of angioedema related to ACE inhibitors, severe renal artery stenosis, or known hypersensitivity to either component should avoid it. Those with advanced kidney disease, significant liver problems, or heart failure with decompensation require careful evaluation by a prescriber.

If you manage blood pressure alongside other conditions, you can also review our condition hub for Hypertension to explore related therapies and educational content.

Dosage and Usage

Follow your prescriber’s exact directions. This combination is typically taken once daily, at the same time each day. You may swallow the tablet with water, with or without food. If you are switching from separate tablets, your clinician may match the dose strengths already in use. Starting therapy and dose adjustments should follow the official label and your prescriber’s guidance.

Limit or avoid alcohol until you know how the tablet affects you. Dizziness can occur, especially when first starting. Stand up slowly if you feel lightheaded. Do not crush or split unless your clinician confirms it is appropriate for your specific tablet.

When discussing options, mention if you have used perindopril amlodipine products before, and share any side effects you experienced. Report cough, ankle swelling, or significant fatigue if they appear or worsen.

Strengths and Forms

The treatment is available as film‑coated tablets in several fixed‑dose combinations. Availability can vary by country and manufacturer. Examples published in product monographs include 3.5/2.5 mg, 7/5 mg, and 14/10 mg strengths. Your prescriber will select a pairing that fits your current regimen and clinical goals.

Some regions market this combination as branded viacoram as well as unbranded generics. Color, shape, and imprint may differ by manufacturer. Not all strengths are stocked at all times.

Missed Dose and Timing

If you miss a dose, take it when you remember the same day. If it is close to your next scheduled time, skip the missed dose and resume your regular schedule. Do not take two doses at once. Consistency matters; setting a phone alarm or using a pill organizer can help.

Storage and Travel Basics

Store tablets at room temperature in a dry place away from excess heat and moisture. Keep the medicine in the original blister or bottle with the label intact and out of reach of children and pets. When traveling, carry it in hand luggage, along with a copy of your prescription and a current medication list. If crossing borders, pack enough for your trip and a little extra in case of delays. Use a secure, opaque container to protect from light as instructed on the package. For online orders, packaging aims to safeguard integrity in transit; follow any storage directions on arrival.

Benefits

This combination reduces daily pill burden by putting two agents into a single tablet. The dual mechanism may help more patients reach blood pressure targets compared to a single class alone. Consolidating doses can make routines simpler, which may support regular use over time. Once‑daily administration is convenient for many schedules.

By controlling pressure more consistently, the therapy may assist in lowering risk for complications associated with long‑term hypertension. It also helps clinicians tailor treatment, as the components can address different contributors to elevated pressure. For more cardiovascular options, browse our Cardiovascular category.

Side Effects and Safety

• Cough or throat irritation
• Dizziness or lightheadedness
• Headache
• Flushing or warmth
• Ankle or leg swelling
• Fatigue
• Nausea or stomach upset

Serious effects can include angioedema (swelling of face, lips, tongue), severe hypotension, kidney function changes, high potassium, or worsening chest pain. Stop the medicine and seek urgent care if you think you have angioedema or a severe reaction. People with diabetes should monitor closely when starting or changing doses, as blood pressure shifts can affect how you feel with existing therapies.

Drug Interactions and Cautions

Tell your prescriber about all medicines, supplements, and herbal products you use. Interactions of note include:

• Potassium‑sparing diuretics or potassium supplements, which can raise potassium
• NSAIDs, which may affect kidney function and blunt antihypertensive effect
• Aliskiren in diabetes, which is generally avoided with ACE inhibitors
• Lithium, with potential for increased levels
• Strong CYP3A4 inhibitors or inducers that may affect amlodipine exposure
• High‑dose simvastatin, which may require dose limits with amlodipine
• Grapefruit products, which can raise amlodipine levels in some people

Use caution when combining with other agents that lower pressure, including alpha‑blockers or nitrates. Defer to the official label and your clinician’s instructions for personalized guidance.

What to Expect Over Time

Blood pressure response usually builds progressively with consistent daily use. Some people notice lightheadedness when standing at first; this often eases as your body adapts. Swelling at the ankles can occur with calcium channel blockers; your prescriber may adjust plans if it becomes troublesome. Keeping a home log, taking the tablet at the same time daily, and attending check‑ins can help your care team fine‑tune your regimen. Do not stop suddenly without medical advice.

Compare With Alternatives

Fixed‑dose combinations are one path to stronger control when single therapy is not sufficient. If a different approach is preferred, your prescriber may consider separate agents. Options we carry include Amlodipine 100 Tablets as a calcium channel blocker and Ramipril as an ACE inhibitor. Another calcium channel blocker option is nifedipine extended‑release, which some patients use in place of amlodipine when appropriate.

Pricing and Access

We source through licensed partners to support canadian pricing for U.S. patients. You can review current availability, see options for a cash price, and compare strengths before you add to cart. Checkout is encrypted, and we provide clear order status updates. For limited‑time offers, visit our Promotions page. Orders are fulfilled with US delivery from Canada after prescription verification.

Availability and Substitutions

Supply can vary by strength and manufacturer. If a requested pairing is unavailable, your prescriber may recommend an alternative dose combination or separate tablets to maintain continuity. We cannot guarantee restock dates, but we can notify you if an item returns to inventory.

Patient Suitability and Cost-Saving Tips

This therapy may suit adults who need two classes for blood pressure control and prefer one tablet each day. It is generally not suitable during pregnancy or for anyone with a prior ACE‑inhibitor–related angioedema. People with reduced kidney function, liver impairment, or significant aortic stenosis need tailored assessment.

To manage costs, consider multi‑month refills if your prescriber supports it, which can reduce per‑fill fees. Set refill reminders so you never run out, especially before travel. If you are paying out of pocket, compare available strengths that meet your clinical plan; sometimes a single higher‑strength tablet directed by your prescriber may be more economical than multiple lower‑strength tablets.

Questions to Ask Your Clinician

• Is a fixed‑dose combination appropriate for my current blood pressure goals?
• Which starting strength best matches my existing regimen?
• How should I monitor blood pressure at home after starting this tablet?
• What side effects should prompt a call or visit?
• Could ankle swelling be managed by timing, dosage, or an alternative?
• Do any of my current medicines raise my potassium or interact with amlodipine?
• If we need changes later, should we adjust one component or both?

Authoritative Sources

Servier Viacoram Product InformationHealth Canada DPD: ViacoramDailyMed: Amlodipine Tablets

Ready to get started? Place your order today for prompt, express shipping with US shipping from Canada. This information is educational and not a substitute for your clinician’s advice or the official label.