Sertraline Tablets for Depression

Sertraline is a selective serotonin reuptake inhibitor used for mood and anxiety conditions. It treats depression, obsessive‑compulsive disorder, panic disorder, social anxiety, post‑traumatic stress disorder, and premenstrual dysphoric disorder. This page explains uses, safety, strengths, and how you can order, even if you plan to pay without insurance.

What Sertraline Is and How It Works

This SSRI increases serotonin levels in the brain, which can help improve mood, reduce anxiety, and lessen intrusive thoughts. It is the Zoloft generic and is widely used under clinical guidance. If you live in the U.S., access is supported with US shipping from Canada through our partner network. Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

It works by blocking serotonin reuptake at nerve synapses. Over time, this may help stabilize mood and reduce symptoms across several diagnoses. Effects are gradual and depend on the prescribed dose and consistent use.

Who It’s For

Healthcare professionals prescribe this medicine for adults with major depressive disorder and other approved conditions. It is also used for obsessive‑compulsive disorder, panic disorder, social anxiety disorder, post‑traumatic stress disorder, and premenstrual dysphoric disorder. Learn more about these conditions in our guides on Depression, Obsessive Compulsive Disorder, and Panic Disorder.

People with a history of bipolar disorder, seizures, angle‑closure glaucoma, significant liver impairment, or known hypersensitivity should discuss risks with a clinician. Avoid use with monoamine oxidase inhibitors or within the required washout periods. Children and adolescents require careful monitoring for mood changes.

Dosage and Usage

Take once daily at the same time, with or without food. Swallow tablets whole with water. Prescribers often start at a low dose and adjust in steps based on response and tolerability. For some conditions, a lower starting dose may be used to reduce early side effects. The prescribed amount should not exceed sertraline 200 mg per day according to labeling.

Increase schedules typically allow at least one week between adjustments. If stomach upset occurs, taking it after a meal may help. Consistency supports better symptom control. Do not change your dose or stop suddenly without medical guidance, as withdrawal symptoms can occur.

Strengths and Forms

Tablet forms are the most common presentation. Many partner pharmacies offer scored tablets for flexible dosing under a prescriber’s direction. Availability can vary by supplier and stock.

• Common tablet strengths include 25 mg, 50 mg, and 100 mg.
• Generics may differ in shape or imprint but contain the same active ingredient.
• Check the label for excipients if you have sensitivities to dyes or fillers.

If your prescriber recommends a specific manufacturer, let our team know during checkout. This helps match your existing therapy when possible.

Some patients use liquid formulations when tablets are not suitable. If you need a liquid option, speak with your prescriber about alternatives available through our Mental Health category.

Missed Dose and Timing

If you miss a dose, take it when you remember, unless it is close to your next scheduled dose. If it is near the next dose, skip the missed dose and continue as scheduled. Do not take extra tablets to make up for a missed dose. Keeping a daily reminder or using a pill organizer can reduce missed doses.

Storage and Travel Basics

Store tablets at room temperature in a dry place, away from excess heat and moisture. Keep them in the original, child‑resistant container with the prescription label. Do not use tablets that are chipped or degraded. When traveling, carry your medicine in your hand luggage and bring a copy of your prescription.

• Protect from moisture and direct light.
• Keep out of reach of children and pets.
• Use a travel pill case and keep the labeled bottle nearby for reference.
• When crossing time zones, take it at your usual local time the next day.

If your trip involves security screening, keep the pharmacy label visible. A written medication list can also help in case of emergencies.

Benefits

This treatment is taken once daily and used across several conditions, which simplifies routines for many patients. Tablets allow titration to an individualized dose. The medicine is available as a generic, which may offer lower cash costs compared with some branded options. Many people find it easier to continue care when they can refill consistently and understand expected effects.

Side Effects and Safety

• Common effects: nausea, diarrhea, indigestion, dry mouth
• Sleep changes: insomnia or drowsiness
• Nervous system: dizziness, tremor, headache
• Sexual effects: decreased libido or delayed orgasm
• Sweating or appetite changes

Serious risks can include serotonin syndrome, suicidal thoughts or behavior in young people, manic episodes in bipolar disorder, significant bleeding with NSAIDs or anticoagulants, hyponatremia, and severe allergic reactions. Seek urgent help for agitation, high fever, muscle stiffness, confusion, or rash with swelling. If you take insulin or sulfonylureas for diabetes, discuss hypoglycemia recognition and monitoring with your clinician.

Read the Medication Guide and follow your prescriber’s instructions. If side effects are concerning or persistent, contact a healthcare professional for advice.

Drug Interactions and Cautions

Do not use with MAOIs, linezolid, or intravenous methylene blue. Avoid pimozide. Use caution with other serotonergic agents such as triptans, tramadol, lithium, or St. John’s wort; this can raise serotonin syndrome risk. NSAIDs, aspirin, and anticoagulants can increase bleeding risk. Alcohol may worsen dizziness or sedation.

Many medicines affect liver enzymes and may change exposure. Tell your prescriber about all medicines and supplements you take, including over‑the‑counter products. If you are pregnant, planning pregnancy, or breastfeeding, discuss current guidance and alternatives. For more context on related therapies, see our article on Fluvoxamine for OCD.

What to Expect Over Time

Improvements often build gradually with steady use. Sleep, energy, or appetite changes may appear first, followed by mood or anxiety relief. Some people feel gastrointestinal upset when starting therapy; these effects may lessen as your body adjusts. If symptoms persist or worsen, consult your prescriber. Stopping suddenly can cause withdrawal symptoms; a supervised taper is typically recommended.

Routine follow‑ups help assess response and tolerability. Using a symptom diary can help you and your clinician track changes. Managing stress, sleep, and therapy attendance can complement medication treatment.

Compare With Alternatives

Branded Zoloft® contains the same active ingredient as this generic. Another SSRI option is Fluoxetine, which some prescribers choose based on history, side‑effect profile, or specific symptoms. For more context on comparative tolerability, see our guide on Zoloft Side Effects.

Pricing and Access

We support transparent choices so you can compare options before checkout. If you pay cash, you can review generic sertraline price ranges and select quantities that fit your plan. Many patients look for sertraline Canadian pricing with Ships from Canada to US fulfillment through our partners. See current availability in our Canada listing and explore related treatments in Mental Health.

Looking for seasonal coupons? Check our latest Promotions. For general mental health options, browse Social Anxiety resources and our overview of Medications for Depression. Checkout is encrypted for your security.

Availability and Substitutions

Stock can vary by strength and manufacturer. If your selection is unavailable, a prescriber may consider an equivalent alternative or another SSRI. Your clinician will determine if a substitution is appropriate for your diagnosis and treatment history.

Patient Suitability and Cost-Saving Tips

This therapy may suit adults with depressive or anxiety‑related disorders who can take an SSRI. It may not be suitable for people with recent MAOI use, uncontrolled seizures, or a known allergy to the active ingredient. Share your full medication list and medical history with your prescriber before starting.

• Multi‑month fills: Fewer refills may lower overall costs.
• Set reminders: Use apps or calendars to stay on schedule.
• Refill early: Request refills before you run low.
• Consistent pharmacy: Helps maintain the same manufacturer when possible.
• Travel prep: Pack enough supply and a written medication list.

Questions to Ask Your Clinician

• Which starting dose fits my diagnosis and history?
• How should we monitor mood, sleep, and anxiety changes?
• What side effects should prompt a call or visit?
• Could other medicines I take raise bleeding or serotonin risks?
• If I plan pregnancy or breastfeeding, what are the options?
• How long should I continue therapy once I feel better?
• What is the plan if this treatment does not meet goals?

Authoritative Sources

Ready to continue? You can buy sertraline online with US delivery from Canada and prompt, express shipping. This information is educational and not a substitute for professional medical advice. Always follow your prescriber’s directions and the official label.