Sprycel® Tablets for Chronic Myeloid Leukemia

Sprycel is a prescription cancer medicine used for certain leukemias. It helps block abnormal signals that drive cancer cell growth. This page explains how it works, who it may suit, and how to use it with US shipping from Canada. Many patients also compare options without insurance to understand cash-pay choices.

What Sprycel Is and How It Works

Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

Sprycel® contains dasatinib, a tyrosine kinase inhibitor. It targets BCR-ABL and other kinases that support cancer cell survival. By blocking these signals, the treatment may slow or stop cancer cell growth. It is approved for Philadelphia chromosome–positive chronic myeloid leukemia and for Philadelphia chromosome–positive acute lymphoblastic leukemia in select settings. See more on the science in our article Dasatinib Mechanism.

This medicine is part of a class often used when intolerance or resistance to a prior tyrosine kinase inhibitor occurs. It can be started in newly diagnosed chronic-phase disease or used after prior therapy failures, according to labeling. Your clinician will determine the appropriate course based on phase, prior response, and lab findings.

Who It’s For

This treatment is indicated for adults with Philadelphia chromosome–positive chronic myeloid leukemia. It also has uses in Philadelphia chromosome–positive acute lymphoblastic leukemia under specific circumstances. Learn more about the condition in our category page Chronic Myeloid Leukemia and broader oncology options in Cancer.

People with a known severe allergy to any component should not take it. Those with a history of significant bleeding, uncontrolled heart rhythm issues, or pulmonary arterial hypertension require careful evaluation. Patients with low blood counts, liver problems, or fluid retention risks need close monitoring. Pregnant patients should avoid this therapy; effective contraception is recommended during treatment and for a period after.

Dosage and Usage

This medicine is typically taken once daily. Your clinician sets the dose and schedule based on disease phase, treatment history, and lab values. Swallow tablets whole with a glass of water. Do not crush, split, or chew the tablets.

It may be taken with or without food. Avoid grapefruit or grapefruit juice as they can affect exposure. If you use antacids, take them several hours apart from your tablet to reduce interaction risk. Proton pump inhibitors are generally not advised with this therapy; discuss alternatives with your clinician. Follow the official label and your clinician’s guidance for all instructions.

Routine blood work is common. Your care team may adjust dosing if lab results, side effects, or interactions arise. Keep a medication list and share it with all healthcare professionals involved in your care.

Strengths and Forms

Tablets are available in multiple strengths to support individualized care. Common presentations include 20 mg, 50 mg, 70 mg, 80 mg, 100 mg, and 140 mg tablets. The Sprycel 100 mg tablet is one option among these dose forms. Availability can vary by dispensing partner and stock. Your prescribed strength will be dispensed as written by your clinician.

Missed Dose and Timing

If you miss a dose, take it when you remember unless it is almost time for the next dose. Do not double up to make up for a missed tablet. If vomiting occurs after a dose, do not take an extra tablet. Resume your usual schedule and contact your clinician for personalized advice if repeated issues occur.

Storage and Travel Basics

Store tablets at room temperature in the original container, away from moisture and light. Keep the bottle tightly closed. Place it out of reach of children and pets. Do not use tablets that are damaged or expired.

When traveling, carry the labeled bottle and a copy of your prescription in your hand luggage. Keep a medication list and your clinician’s contact details with you. Security screening does not harm tablets. If you face long travel or variable climates, keep the bottle protected from excessive heat or humidity. Our partners use temperature-controlled handling when required during transit.

Benefits

As a BCR-ABL tyrosine kinase inhibitor, this therapy may help control disease activity in appropriate patients. Once-daily oral dosing avoids infusion visits. The class offers an option when intolerance or resistance to another tyrosine kinase inhibitor has occurred. Ongoing lab monitoring helps your clinician assess response and safety over time.

Side Effects and Safety

• Headache
• Diarrhea or nausea
• Fatigue
• Skin rash
• Muscle or joint pain
• Fluid retention, including swelling
• Abdominal discomfort

Serious risks can include low blood counts, significant bleeding, pleural effusion, pulmonary arterial hypertension, heart rhythm changes including QT prolongation, and liver problems. Call emergency services for signs of severe reactions like chest pain, sudden shortness of breath, severe dizziness, or signs of a serious allergic reaction. Your clinician will monitor blood counts and may request additional tests, such as chest imaging or electrocardiograms, if needed.

Drug Interactions and Cautions

Strong CYP3A4 inhibitors (for example, ketoconazole or clarithromycin) can raise levels of this medicine. Strong CYP3A4 inducers (such as rifampin or certain anticonvulsants) can lower levels and reduce effectiveness. Avoid grapefruit products. Discuss all acid-reducing therapies; antacids may be separated by several hours, and some acid suppressors may be unsuitable.

Use caution with blood thinners and antiplatelet agents due to bleeding risk. Tell your clinician about herbal supplements, including St. John’s wort. People who are pregnant or may become pregnant should not take this medicine; it may harm a developing fetus. Breastfeeding is not recommended during treatment and for a period after the last dose per labeling.

What to Expect Over Time

Your clinician will monitor blood counts and may measure BCR-ABL levels to assess response. Some effects, such as mild gastrointestinal symptoms or fatigue, may appear early and can improve with supportive care. Fluid retention can occur at any time and requires prompt evaluation. Stay consistent with daily dosing, keep all appointments, and report new symptoms. Do not stop treatment without guidance, as abrupt changes can affect disease control.

Compare With Alternatives

Other approved tyrosine kinase inhibitors are available for similar indications. Your clinician may consider Nilotinib or Bosulif based on your history, tolerability, and lab results. For context on related options, see our article Treats CML and this overview Uses Overview. Your care plan should always align with the official labels and your clinician’s advice.

Pricing and Access

We work to make Canadian pricing straightforward and transparent. Compare options, review the Sprycel price, and see how a Dasatinib price may differ by strength and quantity. You can check availability for US delivery from Canada and view current options before placing an order. For added security, our site uses encrypted checkout.

Looking for savings? Visit Promotions for current offers when available. You can review cash-pay details and confirm requirements before you proceed. Please note that final out-of-pocket amounts vary by prescribed quantity, dispensing partner, and your selections.

Availability and Substitutions

Supply can vary. If an item is temporarily unavailable, a prescriber may recommend an alternative in the same class that fits your history and lab profile. If you are comparing discounts, you can also search for a Sprycel coupon as part of your planning, though availability changes over time. We also publish educational resources to help you discuss substitutions with your care team.

Patient Suitability and Cost-Saving Tips

This medicine may suit adults with Philadelphia chromosome–positive chronic myeloid leukemia or Philadelphia chromosome–positive acute lymphoblastic leukemia when a tyrosine kinase inhibitor is indicated. People with uncontrolled heart rhythm disorders, active significant bleeding, or pulmonary arterial hypertension need special consideration. Those with low blood counts or liver issues will need close monitoring.

To manage costs, consider multi-month quantities if appropriate, which may reduce per-unit pricing. Set refill reminders so you do not miss doses. Explore generic options when your clinician agrees; some patients consider Nilotinib Uses content to understand class differences. If your clinician discusses dasatinib specifically, you can review Dasatinib Mechanism again and compare options like Dasatinib from Canada within our catalog.

Questions to Ask Your Clinician

• Treatment goals: what response markers will be monitored
• Safety plan: how to watch for bleeding or fluid buildup
• Interaction risks: managing acid reducers and other medicines
• Monitoring: how often labs and any ECGs are needed
• Duration: when to reassess and consider treatment changes
• Supportive care: plans for nausea, fatigue, or rash

Authoritative Sources

Ready to proceed? You can place your order for these tablets with Ships from Canada to US and prompt, express shipping. This content is educational and does not replace the advice of your clinician.