Leukemia is a cancer that targets the blood and bone marrow. Patients with such conditions require specialized treatments to manage their progression. One such medication, Tasigna, has shown significant efficacy in treating specific types of leukemia, offering hope and improved outcomes for many patients.
Let’s learn more about Tasigna, including its uses, cost, generic name, and important considerations like interactions with coffee.
What is Tasigna?
Tasigna (generic name: nilotinib) is a medication used to treat Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML) in adults. It belongs to a class of drugs known as tyrosine kinase inhibitors, which block abnormal protein that signals cancer cells to multiply. It helps stop the spread of cancer cells.
Uses of Tasigna
Tasigna uses for:
- Treatment of Ph+ CML in the chronic phase: It is used in patients who are newly diagnosed or who did not respond well to other treatments.
- Treatment of Ph+ CML in the accelerated phase: It is also used when the disease has progressed from the chronic phase but is not yet in the blast phase.
Tasigna Dosage
The recommended dosage of Tasigna varies depending on the phase of chronic myeloid leukemia and the patient’s overall health. Typically, the dosage is:
- For newly diagnosed Ph+ CML in chronic phase: 300 mg taken twice daily.
- For chronic and accelerated phase Ph+ CML that has resistance or intolerance to prior therapy: 400 mg taken twice daily.
Tasigna should not be taken with an empty stomach. Be sure to take the medication at least one hour before or two hours after a meal. Swallow the capsules whole with water without breaking, chewing, or opening them.
Tasigna and Coffee
One important consideration for patients taking Tasigna is its interaction with certain foods and beverages. Specifically, Tasigna and coffee can interact, as coffee can affect the absorption of the medication. Patients are advised to avoid coffee and other caffeinated drinks close to their dosing times to ensure the medication’s effectiveness.
Tasigna Cost
The price for Tasigna oral capsules (150 mg) is approximately $5,285 for a 28-capsule supply, though this can vary depending on the pharmacy. These quoted prices are for customers paying in cash and are not applicable to those with insurance plans, making it a substantial financial consideration for many patients. Patients should discuss with their healthcare provider or pharmacist about potential cost-saving options, such as generic alternatives or financial assistance programs.
Tasigna Generic Name and Availability
Tasigna generic name is nilotinib. On January 5, 2024, a significant milestone was achieved when the U.S. Food and Drug Administration (FDA) approved a generic version of Tasigna.
Takeaways
Tasigna is a vital medication for treating certain types of leukemia, offering hope for patients with Ph+ CML. Understanding its full prescribing information, including proper dosage, potential interactions like those with coffee, and the cost, is essential for effective treatment.
By staying informed and proactive about their treatment, patients can better manage their condition and work towards achieving the best possible outcomes with Tasigna.
Frequently Asked Questions (FAQs)
What should I do if I miss a dose?
If you miss a dose of Tasigna, take it as soon as you remember unless it is within 12 hours of your next dose. Do not take two doses at the same time to make up for the missed dose. You may skip the dose you missed and then continue with your regular dosing schedule.
Can I take other medications while on Tasigna?
It is important to be aware that certain medications may interact with Tasigna, potentially affecting its effectiveness or increasing the chances of experiencing adverse effects. Before initiating Tasigna treatment, always make sure to disclose to your healthcare provider all other drugs, supplements, or herbal medications you have.
What should I discuss with my healthcare provider before starting Tasigna?
Before starting Tasigna, discuss your medical history with your healthcare provider, especially if you have a history of heart problems, liver disease, or any other significant health conditions. Also, inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.