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Stelara® Prefilled Syringe for Plaque Psoriasis and IBD
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Price range: $5,999.99 through $6,599.99
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Stelara prefilled syringes are prescription biologic injections used for immune-mediated conditions. They target specific inflammatory pathways to help reduce symptoms and maintain control. This page explains how the treatment works, who it may suit, and how you can manage ordering and storage with US shipping from Canada. You can also learn about costs if you pay without insurance.
What Stelara® Is and How It Works
Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing. Stelara® contains ustekinumab, a monoclonal antibody that binds interleukin-12 and interleukin-23. By blocking these cytokines, the therapy can reduce inflammation that drives plaque psoriasis, psoriatic arthritis, Crohn’s disease, and ulcerative colitis. It is administered as a subcutaneous injection and is used for induction or maintenance depending on the condition. Always follow the official prescribing information and your prescriber’s guidance.
Who It’s For
This medicine is approved for adults with moderate to severe plaque psoriasis and active psoriatic arthritis. It is also indicated for adults with moderate to severe Crohn’s disease or ulcerative colitis who meet label criteria. Some adolescents with plaque psoriasis may be candidates where approved; defer to the label for age specifics.
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People with active serious infections should not start the treatment. Those with chronic or recurrent infections, a history of tuberculosis, or underlying immunosuppression require careful evaluation. Tell your healthcare professional about prior or planned vaccines, especially live vaccines. Review all medicines you use, including biologics and immunomodulators.
Dosage and Usage
Dosing depends on the condition. For psoriasis and psoriatic arthritis, treatment often begins with two starting doses followed by maintenance every 12 weeks. For Crohn’s disease and ulcerative colitis, patients typically receive an IV induction under medical supervision, then transition to a subcutaneous maintenance schedule. Your prescriber will choose the schedule and strength appropriate to your weight and indication as described in the official label.
Give injections subcutaneously in the thigh, abdomen, or upper arm, rotating sites. Inspect the syringe; do not use if the liquid is discolored, frozen, or contains large particles. Allow the syringe to reach room temperature per the label before injecting. Do not shake. If you need training, ask your prescriber or pharmacist.
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Strengths and Forms
Prefilled syringes are commonly supplied in two strengths for maintenance use. Availability may vary by market and over time.
- 45 mg/0.5 mL prefilled syringe
- 90 mg/mL prefilled syringe
Packaging may include a single-dose prefilled syringe with a needle safety feature. Check the carton and leaflet for the specific presentation you receive.
Missed Dose and Timing
If you miss a maintenance dose, take it as soon as you remember unless it is close to your next scheduled injection. Then follow your regular schedule. Do not take two doses at once. If you are unsure how to realign your calendar, contact your prescriber for guidance consistent with the label.
Storage and Travel Basics
Store syringes refrigerated in the original carton to protect from light. Do not freeze. If needed for travel, the label provides guidance on limited time at room temperature; ask your pharmacist about the specific allowance. Keep out of reach of children. When traveling, carry this medicine in a cooler with gel packs and a copy of your prescription. Avoid leaving it in a hot car. Use temperature-controlled handling when required, and check the solution before use.
Pen Handling and Sharps Disposal
These are prefilled syringes, not pens, but safe injection and disposal are essential.
- Prepare area: wash hands, gather supplies, and clean the site.
- Inspect syringe: check label and liquid; do not shake.
- Inject subcutaneously: pinch skin if advised; follow training materials.
- Activate safety device: keep hands clear of the needle tip.
- Dispose correctly: place the used syringe in an FDA-cleared sharps container.
Do not recap needles. Follow local rules for sharps disposal. If you need a container, ask your pharmacy.
Benefits
This treatment targets IL-12/23, which may help reduce plaques, joint symptoms, and intestinal inflammation. In maintenance phases, injections are spaced weeks apart, which some patients find convenient. Subcutaneous administration at home, after training, may reduce clinic visits compared with certain infusion-only therapies.
Side Effects and Safety
- Common: nasopharyngitis, headache, fatigue, injection-site reactions
- Digestive: nausea, abdominal discomfort
- Skin: redness, mild itching at the injection site
Serious risks can include infections (bacterial, viral, fungal), reactivation of tuberculosis, and rare hypersensitivity reactions. Malignancy risk has been observed with immunomodulators; discuss your personal history with your prescriber. Seek urgent care for signs of serious infection, severe rash, shortness of breath, chest pain, confusion, or high fever. This medicine may affect vaccine responses; live vaccines are generally avoided during treatment per label guidance.
Drug Interactions and Cautions
Tell your clinician about all prescription, OTC, and herbal products you use. Combining with other biologics that impact the immune system can increase risks. Live vaccines are typically avoided during and for a period after therapy; inactivated vaccines may be considered. Screening for tuberculosis is recommended before initiation. Inform your prescriber if you have a history of cancer, chronic infections, or if you are pregnant or breastfeeding; decisions should follow official labelling and clinical judgment.
What to Expect Over Time
Responses can vary by condition and prior therapy. Some people notice gradual improvement in skin plaques or gastrointestinal symptoms during maintenance. It may take multiple doses to assess effect. Adherence to the schedule is important; setting reminders and aligning refill dates can help. If your maintenance plan uses Ustekinumab Prefilled Syringe 90 mg, your prescriber will determine the appropriate interval per the label.
Compare With Alternatives
Several other approved options address similar conditions. For plaque psoriasis and psoriatic arthritis, IL-17 or IL-23 inhibitors such as Cosentyx may be considered by prescribers based on history and response. For Crohn’s disease and ulcerative colitis, anti-TNF agents like Humira Prefilled Syringe are established alternatives. Your clinician will review benefits, safety, and administration schedules to select a therapy aligned with your needs.
Pricing and Access
Review Canadian pricing and compare options with US delivery from Canada. This page helps you see current availability, typical cash-pay considerations, and ways to coordinate refills with your prescriber. If you are exploring ways to lower out-of-pocket costs, check any manufacturer support programs listed on official sites. For seasonal or site-specific offers, see our Promotions.
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For self-pay orders, you can review total charges during checkout before confirming. Taxes, dispensing fees, and courier options appear at checkout. Pricing may vary by supply source, strength, and pack size. For broader context on self-pay costs, see our article on Drug Costs Without Insurance. We use encrypted checkout to protect your information.
Availability and Substitutions
Supply can vary. If this item is unavailable, your prescriber may recommend an alternative from the same or a different class based on your condition and prior response. Exact-match keyword: Stelara Prefilled Syringe savings
Learn more about your condition and related therapies in our condition hubs: Psoriasis, Psoriatic Arthritis, Crohn’s Disease, and Ulcerative Colitis. You can also explore the broader Immunology category or view our Country Of Origin Canada listings.
Patient Suitability and Cost-Saving Tips
This medicine may suit adults with moderate to severe disease who have failed or are intolerant to other therapies, as outlined in the label. It may not be appropriate for patients with active serious infections or those receiving certain live vaccines. Your prescriber may order tests before and during therapy to monitor safety.
To reduce total costs, consider multi-month supplies when appropriate, and set refill reminders tied to your injection calendar. Align follow-up appointments with scheduled doses to avoid lapses. Exact-match keyword: Stelara Prefilled Syringe online
For additional background on immune conditions, see our overview on Autoimmune Diseases. For skin-specific biologics education, our feature Exploring Cosentyx Uses may provide useful context to discuss with your clinician.
Questions to Ask Your Clinician
- Indication fit: how this therapy aligns with my diagnosis
- Safety checks: vaccines, TB screening, and infection history
- Dosing plan: induction, maintenance interval, and monitoring
- At-home use: injection training and site rotation tips
- Travel: storage steps and documentation for trips
- Alternatives: when to consider switching therapies
Authoritative Sources
| Reference | Link |
|---|---|
| US Prescribing Information (FDA/PI) | FDA Label Repository |
| Health Canada Drug Product Database | Health Canada DPD |
| Manufacturer Product Page | Janssen |
Ready to proceed with your prescription? Order through BorderFreeHealth with prompt, express shipping that Ships from Canada to US. This content is for general information only and does not replace the advice of your healthcare professional. Always follow your prescriber and the official label.
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Shipping Countries:
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How is the prefilled syringe different from the vial or IV infusion?
The prefilled syringe is designed for subcutaneous self-injection after training. It contains a single dose for maintenance treatment. Some conditions, like Crohn’s disease or ulcerative colitis, begin with an IV induction given under supervision, then you continue with subcutaneous maintenance using the syringe. Your clinician will decide which form you need based on the label and your clinical history.
Can I receive vaccines while using this medicine?
Live vaccines are generally avoided during and for a period after treatment with ustekinumab. Inactivated vaccines, such as the flu shot, may be considered. Timing and suitability depend on your individual risk factors and official labelling. Discuss your vaccination plan with your prescriber before starting and during therapy.
What should I do if I develop signs of infection?
Contact your healthcare professional promptly if you develop fever, cough, painful urination, persistent diarrhea, or other signs of infection. People on immunomodulators can have higher infection risk. Your clinician may pause treatment or investigate further. Seek emergency care for severe symptoms like shortness of breath, chest pain, or confusion.
How do I store syringes during travel?
Keep syringes in the original carton under refrigeration before travel. When traveling, use a cooler with gel packs and keep the medicine out of direct sunlight. Do not freeze. Carry your prescription and allow the syringe to warm as directed before injecting. If travel storage is challenging, ask your pharmacist about the label’s room-temperature allowance.
Are there special steps for injection site rotation?
Rotate sites among the abdomen, thigh, and upper arm to reduce local irritation. Avoid areas that are tender, bruised, scarred, or affected by psoriasis plaques. Clean the site with an alcohol swab, let it dry, and inject at the angle taught during training. If a site becomes painful or very red, contact your prescriber.
Will this medication interact with other biologics or immunosuppressants?
Combining multiple systemic immunomodulators can increase risks. Tell your prescriber about all biologics, JAK inhibitors, corticosteroids, and other agents you use. Your clinician will consider whether combinations are appropriate or whether to transition between therapies according to the label and your clinical situation.
How soon might I notice changes in symptoms?
Responses vary. Some people notice gradual changes over several weeks as maintenance dosing continues, while others may take longer. The key is consistent dosing and follow-up with your clinician to evaluate response and safety. Your prescriber will use label-based criteria to decide if the therapy should be continued or adjusted.
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