Vetoryl® Capsules for Cushing's in Dogs

Vetoryl® is a prescription trilostane medicine used to manage Cushing’s disease in dogs. It helps reduce excess cortisol, which can improve thirst, urination, appetite, and coat quality over time. We provide US delivery from Canada so you can request refills with transparent costs, even without insurance.

What Vetoryl Is and How It Works

Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

This therapy contains trilostane, which blocks an adrenal enzyme involved in cortisol production. By lowering cortisol, the treatment can help control the symptoms of hyperadrenocorticism in dogs. The effect is dose-dependent and requires veterinary monitoring to keep cortisol in a safe range.

This medicine is classified as trilostane capsules for dogs, and it is given with food. Your veterinarian tracks response with clinical checks and laboratory tests as recommended on the official label.

Who It’s For

This product is used for canine hyperadrenocorticism, often called Cushing’s disease. It is appropriate for many dogs with pituitary-dependent disease and may also be used in some cases of adrenal-dependent disease under specialist guidance. Dogs with uncontrolled kidney, liver, or heart disease may need additional evaluation before starting therapy.

Vetoryl for Cushing’s in dogs is not for human use. It should not be used during pregnancy or in breeding animals unless the prescriber decides the benefits outweigh risks. Discuss the full medical history and current medicines with your veterinarian before starting.

Dosage and Usage

Follow the dispensing label and your veterinarian’s instructions. Capsules are typically given once daily with food. Some dogs may do better with divided dosing, depending on monitoring results and clinical response. Do not change the dose or schedule without veterinary direction.

Timing matters. Give doses at the same time each day with a meal. Your veterinarian will determine when to check labs and how to interpret clinical signs such as thirst, urination, appetite, energy level, and panting. Routine monitoring is essential for ongoing safety.

If your veterinarian provides a new plan after testing, follow their guidance exactly. Keep a simple log of doses and observed changes. Bring this log to checkups to support informed decisions.

Strengths and Forms

The medicine is supplied as oral capsules in multiple strengths. Common options include 5 mg, 10 mg, 20 mg, 30 mg, 60 mg, and 120 mg. Availability may vary by pharmacy and inventory.

Some caregivers look specifically for Vetoryl 10mg capsules when a precise dose is needed. Your prescriber will select a strength or combination that fits your dog’s plan.

Missed Dose and Timing

If you miss a dose, give the next dose at the usual time with food. Do not double up to make up for a missed dose. If more than one dose is missed, contact the veterinary clinic for guidance. If your dog vomits shortly after dosing, ask your veterinarian whether to repeat or wait until the next scheduled dose.

Storage and Travel Basics

Store capsules at room temperature in the original child-resistant container. Keep the bottle tightly closed and away from moisture. Protect from light and keep out of reach of children and pets. Do not use after the expiration date on the label.

When you travel, carry the labeled container in your hand luggage. Pack enough for the trip plus a few extra days in case plans change. Bring a copy of the prescription or a clinic contact card if airport or hotel staff ask about the medicine. For mail orders, our partners use temperature-controlled handling when required. At home, follow your clinician’s storage advice.

Benefits

This treatment can help manage excessive thirst, frequent urination, increased appetite, panting, and changes in skin and coat associated with hyperadrenocorticism. Many caregivers find routine dosing with food straightforward. The therapy is available in multiple strengths, which helps prescribers tailor dosing. Ongoing monitoring aims to balance symptom control with safety.

Over time, your dog may show improved comfort and daily routines. Response varies, and veterinarians use both lab results and clinical signs to guide adjustments. Consistent dosing and scheduled rechecks support the best outcomes.

Caregivers sometimes search for Vetoryl capsules when they need a steady supply aligned with their veterinarian’s plan. You can request refills through our site when your prescriber authorizes them.

Side Effects and Safety

Common side effects can include reduced appetite, vomiting, diarrhea, lethargy, or mild weakness. These may be temporary, but persistent or severe issues need veterinary attention. Less common risks include oversuppression of adrenal hormones, which can resemble Addison’s disease and may cause severe lethargy, collapse, weakness, vomiting, or diarrhea. This requires urgent care.

• Reduced appetite or picky eating
• Vomiting or loose stools
• Lethargy or decreased activity
• Electrolyte changes on lab tests
• Rarely, adrenal complications requiring immediate care

If your dog shows concerning signs, contact your veterinarian promptly. Seek emergency help for collapse, severe weakness, or persistent vomiting. Report all adverse events to your prescriber.

Drug Interactions and Cautions

Tell your veterinarian about all medicines, supplements, and diets your dog uses. Caution is advised with potassium-sparing diuretics, ACE inhibitors, mitotane, ketoconazole, and other therapies that can affect adrenal function or electrolytes. Your clinician may adjust monitoring schedules if combinations are necessary.

Dogs with significant liver, kidney, or cardiac disease may need closer follow-up. Always follow the official label for testing intervals and clinical checks.

What to Expect Over Time

Prescribers aim for steady control of cortisol. Many dogs show gradual improvement in thirst and urination first, with coat and skin changes evolving more slowly. Your veterinarian uses exams and blood tests to guide dosing. Do not expect changes overnight; consistency and monitoring are key. If response seems incomplete or side effects occur, your clinician may reassess timing, strength, or overall plan.

Routine follow-ups are part of responsible care. Bring notes on appetite, water intake, urination frequency, activity, and behaviors like panting. These observations help your clinician optimize therapy.

Compare With Alternatives

Other approved options for canine Cushing’s include mitotane, which works differently and requires careful monitoring. Selegiline may be considered in select pituitary cases. Your prescriber will choose based on diagnosis, comorbidities, and your dog’s history. For endocrine therapy in other conditions, see Zycortal for adrenal insufficiency management and Cerenia for nausea related to various canine illnesses. For additional context, explore our Cushings Syndrome page.

Pricing and Access

Many caregivers compare options to understand the Vetoryl price and typical out-of-pocket amounts. We show current availability so you can discuss choices with your prescriber before placing a request. You can review Canadian pricing details and request refills when your veterinarian authorizes them. We support US shipping from Canada with clear checkout steps and status updates by email.

Looking for savings? See our periodic offers on the Promotions page. For broader options, browse Pet Medications or review country options under Canada. Price transparency helps you plan with your clinician.

Availability and Substitutions

Supply can vary by strength. If a strength is temporarily unavailable, your veterinarian may suggest a different combination or an alternative therapy. We cannot guarantee dates for restocking. Your prescriber should direct any substitutions to keep dosing clinically appropriate.

Patient Suitability and Cost-Saving Tips

Good candidates are dogs with a confirmed diagnosis and an established monitoring plan. Dogs with advanced organ disease, pregnant or breeding animals, or those on interacting medicines need individualized risk‑benefit discussions. Always follow label-based testing schedules.

To manage costs, consider multi-month refills when your veterinarian deems the dose stable. Align rechecks with refill timing to reduce separate trips. Use reminders on your phone to avoid missed doses. Keep a simple log of appetite, thirst, activity, and stools; better data can reduce unnecessary repeat visits. If your prescriber approves, synchronize prescriptions for other long-term medicines to combine fulfilment.

Questions to Ask Your Clinician

• Diagnosis details: pituitary-dependent or adrenal-dependent disease?
• Starting plan: dose with food, and what time each day?
• Monitoring: which tests and how often at first?
• Safety: signs of oversuppression that need urgent care?
• Interactions: any medicines, supplements, or diets to avoid?
• Adjustments: when might split dosing be considered?
• Long-term goals: which symptoms should improve first?

Authoritative Sources

Dechra Veterinary Products

FDA CVM FOI Summary

Health Canada Drug Product Database

Learn More About Pet Care

For supportive information, see Gabapentin For Dogs for pain and seizure guidance, and Insulin For Dogs for managing diabetes. If infections are present, your vet may discuss options such as Doxycycline For Dogs And Cats or Clavamox For Cats And Dogs when clinically appropriate.

Checkout is encrypted, and a prescription is required and verified before dispensing.

Ready to proceed? You can buy Vetoryl with prompt, express shipping after your veterinarian approves your request. This page is informational and does not replace veterinary advice.