Zydelig

Zydelig is a cancer medicine used to treat certain types of blood cancers like chronic lymphocytic leukemia (CLL), follicular lymphoma (FL), and small lymphocytic lymphoma (SLL). It works by blocking a specific protein in cancer cells, which helps slow their growth and can lead to cancer cell death.

Benefits

• Targets cancer at the source by blocking the PI3K delta protein, which helps cancer cells survive.
• Can help shrink lymph nodes and improve blood counts in patients with leukemia or lymphoma.
• Taken as a tablet at home — no hospital visits needed for infusions.
• Offers an option for patients who didn’t respond to other treatments.
• Can be used together with other medications for better results in some cases.

Dosage

• The usual dose is 150 mg twice a day.
• Take tablets at the same time every day, with or without food.
• Swallow whole — do not chew, crush, or split the tablet.
• Your doctor may adjust your dose if you have side effects.

Warnings and Precautions

• May cause serious infections — let your doctor know if you have fever, chills, or cough.
• Can lead to liver problems — regular blood tests are important.
• Risk of severe diarrhea or bowel inflammation — report stomach pain or changes in bowel movements.
• Not safe during pregnancy or breastfeeding — use birth control during and after treatment.
• May cause lung inflammation — tell your doctor if you have trouble breathing.

Usage Instructions

• Take exactly as your doctor prescribed — don’t skip doses or stop suddenly.
• If you miss a dose, take it as soon as you remember unless it’s almost time for the next dose.
• Do not double up to make up for a missed dose.
• Keep up with regular medical visits and blood tests to monitor for side effects.

Storage Information

• Store at room temperature (20°C to 25°C), away from moisture and heat.
• Keep the tablets in their original container.
• Store out of reach of children.

Common Side Effects

Mild to moderate effects: diarrhea, tiredness, fever, nausea, cough, and stomach pain.
Serious (seek medical attention): signs of infection (fever, chills), liver issues (yellow skin, dark urine), lung problems (shortness of breath), or severe abdominal pain and persistent diarrhea.