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Uloric Side Effects, Dosing

Post written by BFH Staff Writer on August 5, 2022
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Uloric, a common brand for Febuxostat, is a once-in-a-day medication that helps prevent the development of gout flares. Uloric stops xanthine oxidase, an enzyme responsible for producing uric acid. With that, it aids in lowering uric acid levels in the body to prevent the formation of chronic gout and kidney stones.

Make sure you have disclosed any medical issues to your healthcare provider before starting your medication with Uloric. This is crucial if you have underlying health conditions like:

  • Liver or kidney problems
  • History of cardiovascular disease
  • Pregnancy or planning a pregnancy
  • Breastfeeding or planning to breastfeed

Meanwhile, the following are the most common side effects of Uloric:

  • Joint pain
  • Nausea
  • Skin rash
  • Dizziness

Other serious side effects of Uloric include:

  • Mycardial infarction or any cardiovascular events
  • Weakness
  • Numbness in extremities
  • Shortness of breath

Uloric Dosing

Uloric should be taken in doses of 40 mg or 80 mg once daily. Additionally, the suggested standard dosage of Uloric is 40 mg once per day.

On the other hand, the recommended dose of Uloric is 80 mg once day for patients who do not reach a serum uric acid (sUA) less than 6 mg/dL after two weeks.

No change of dosage is required for patients with mild to severe hepatic impairment

What is Uloric Used For?

Uloric, a generic brand name of Febuxostat, is a prescription medicine that prevents xanthine oxidase (XO) to lower blood uric acid levels in adults with gout. Uric acid comes from substances called purines. Most purines either come from within your body or from food and drinks.

Alternative Drugs

Here are some of the alternative drug options for Uloric:

  • Allopurinol – It is used to treat high uric acid levels caused by gout, kidney stones, and cancer treatment, but it should not be used to treat asymptomatic high uric acid levels. If a rash develops while taking Allopurinol, the medication must be stopped immediately and urgent medical attention should be sought.
  • Zyloprim – It is used to treat gout, kidney stones, and prevent an uric acid from increasing especially among patients undergoing chemotherapy for cancer.

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