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Addyi® Tablets for Hypoactive Sexual Desire Disorder
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Addyi is a prescription tablet for low sexual desire in certain adults. It helps address reduced sexual interest that causes distress. This page explains how it works, who it’s for, and how to use it, with US delivery from Canada. You can check addyi cost without insurance and learn about access options.
What Addyi Is and How It Works
Addyi® contains flibanserin, a nonhormonal treatment for acquired, generalized hypoactive sexual desire disorder (HSDD) in premenopausal adults. It acts on serotonin and dopamine systems in the brain. These pathways may influence sexual interest and related distress.
Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.
Researchers believe this therapy modulates neurotransmitters to help restore balance. The effect is not immediate. Consistent bedtime dosing is important. Unlike on-demand options, flibanserin is taken daily.
For background on HSDD and related concerns, see our condition guide for Hypoactive Sexual Desire Disorder. Some people also explore vaginal therapies for menopause-related symptoms; learn more in Imvexxy Uses.
Who It’s For
This medicine is indicated for acquired, generalized HSDD in premenopausal adults. Symptoms should not be due to relationship stress, other medical conditions, or other medicines. An addyi prescription is not approved for postmenopausal adults or for men.
Avoid use if you have liver problems. Avoid use with strong or moderate CYP3A4 inhibitors. Alcohol use near dosing increases the risk of low blood pressure and fainting.
If depression or anxiety contributes to low desire, a clinician may address those conditions separately. For related reading, see Escitalopram Side Effects and Prozac Side Effects.
Dosage and Usage
Per the label, take the addyi pill at bedtime only. Taking it during waking hours increases the risk of dizziness, sleepiness, and accidental injury. Swallow tablets with water. Taking it with or without food is typically acceptable.
Do not drink alcohol within a few hours of bedtime dosing. If you have had three or more alcoholic drinks that evening, skip the dose. Do not drive or operate machinery until at least six hours after taking this medicine.
Your prescriber may reassess response after several weeks. If there is no meaningful improvement by eight weeks, the label advises discontinuation.
Strengths and Forms
This treatment is available as a flibanserin 100 mg tablet. Strength and packaging may vary by manufacturer and country of origin. Availability can change based on supply.
Missed Dose and Timing
If you miss a bedtime dose, skip it and take the next dose at the usual bedtime. Do not take it in the morning. Do not double up to make up a missed dose. Maintaining a regular schedule helps assess benefit and safety.
Storage and Travel Basics
Store tablets at room temperature in the original container. Keep the bottle closed to protect from moisture. Keep out of reach of children and pets. For travel, pack enough for the full trip plus a few extra doses. Carry your prescription label or a copy of your prescription for security checks. If you cross time zones, keep bedtime dosing in your destination’s local time.
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Benefits
This therapy may help increase sexual desire and reduce distress from low interest in premenopausal adults with HSDD. Daily bedtime dosing can simplify routines. Nonhormonal action may suit those who cannot use estrogen-based options. Consistent use allows your prescriber to evaluate response over time.
Side Effects and Safety
- Common effects: dizziness, sleepiness, nausea
- Other effects: fatigue, dry mouth, trouble sleeping
Serious risks include low blood pressure and fainting, especially with alcohol or CYP3A4 inhibitors, or if taken outside of bedtime. Do not drive or perform activities requiring alertness until at least six hours after dosing. Report concerning mood changes, severe dizziness, or fainting to a healthcare professional.
Some antidepressants can affect sexual function. If you use one, discuss potential adjustments with your prescriber. For background, read Escitalopram Side Effects.
Drug Interactions and Cautions
Avoid strong or moderate CYP3A4 inhibitors such as certain azole antifungals, macrolide antibiotics, and some HIV therapies. Avoid alcohol near dosing. Do not use if you have liver impairment. CYP3A4 inducers, including St. John’s wort, may reduce effectiveness. Grapefruit can increase drug levels; discuss dietary considerations with your prescriber.
Other medicines that lower blood pressure or cause sleepiness may increase risks. Provide a full medication list to your clinician. If you start or stop a medicine that affects flibanserin, your prescriber may change plans according to the label.
What to Expect Over Time
Response varies. Some people notice gradual changes in desire and distress over several weeks. Keep consistent bedtime dosing and track symptoms in a simple journal. If you do not see meaningful benefit by eight weeks, talk with your prescriber about next steps. Supportive counseling and addressing contributing factors may improve outcomes.
Compare With Alternatives
Another FDA-approved option for premenopausal HSDD is bremelanotide, an on-demand injectable used before anticipated sexual activity. It works differently and has its own safety profile. Your prescriber can help choose based on your health history and preferences.
When low desire overlaps with mood symptoms, treating an underlying condition may come first. In some cases, an antidepressant like Escitalopram may be considered for mood disorders; sexual side effects vary by agent. For context, see Prozac Side Effects.
For menopause-related discomfort, nonhormonal and hormonal options exist. Explore women’s therapies in Womens Health.
Pricing and Access
We list current addyi price alongside Canadian sourcing details, with fulfilment by licensed partners. Ordering includes pharmacist oversight and verification. You can review offers on our Promotions page when available. We provide transparent information to help you compare value and expected access.
To emphasize cross-border value, orders typically ship via partners that operate across borders, and qualifying items are sent on routes that Ships from Canada to US. For origin details, see Canada. Your card is charged in a secure checkout environment.
Availability and Substitutions
Supply may vary. If the product is not available, a prescriber may recommend an alternative or a later fill when stock returns. Pharmacies dispense only with a valid prescription and according to local regulations.
Patient Suitability and Cost-Saving Tips
This therapy may suit premenopausal adults with acquired, generalized HSDD after an evaluation rules out other causes. It is not for postmenopausal adults, not for men, and not for those with liver impairment. Avoid alcohol near dosing and follow label restrictions.
To help manage costs, consider multi-month fills if appropriate. Set refill reminders to avoid missed doses. Compare options in Womens Health and read condition guidance to prepare for clinical conversations. Discuss insurance coverage, cash-pay approaches, and pharmacy options with your prescriber.
Questions to Ask Your Clinician
- Is my low desire consistent with acquired, generalized HSDD?
- Could another condition or medicine be contributing to symptoms?
- What benefits and risks matter most for me?
- How should I manage alcohol around bedtime dosing?
- What signs mean I should stop and contact you?
- When should we reassess response and next steps?
Authoritative Sources
Health Canada Drug Product Database
Availability of Related Information
Learn more about related therapies and conditions in our articles: Escitalopram Side Effects and broader women’s topics within Imvexxy Uses.
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What is Addyi used for?
Addyi is used to treat hypoactive sexual desire disorder (HSDD) in premenopausal women—low sexual desire that causes distress or relationship problems.
Can I take Addyi during the day?
No, Addyi should always be taken at bedtime to reduce the risk of fainting and low blood pressure.
Can I drink alcohol while taking Addyi?
No, alcohol should be completely avoided because it can cause dangerous side effects like severe low blood pressure and fainting.
How long does it take for Addyi to work?
Some women may start noticing improvements within a few weeks, but a full response may take up to 8 weeks. If there is no benefit after this time, speak with your doctor about stopping the medication.
Is Addyi a hormone?
No, Addyi is a non-hormonal medication that works by affecting brain chemicals involved in sexual desire.
How does flibanserin differ from on-demand options for HSDD?
Flibanserin is taken every night at bedtime. It works on central neurotransmitters involved in sexual interest. On-demand options like bremelanotide are used before anticipated sexual activity. They have different dosing and side effect profiles. Your prescriber will consider health history, preferences, and potential interactions when choosing between daily therapy and an as-needed approach.
Can I drink alcohol while using Addyi?
Alcohol near dosing can increase the risk of low blood pressure and fainting. The label advises bedtime-only dosing and careful counseling about alcohol. If you have consumed three or more alcoholic drinks that evening, skip the dose. Do not drive or operate machinery until at least six hours after taking the tablet. Discuss your alcohol use with your prescriber before starting therapy.
How long should I try this medicine before reassessing?
Your prescriber typically reassesses after several weeks of consistent bedtime dosing. If there is no meaningful improvement by eight weeks, the label recommends discontinuation. Keep a simple symptom journal and share it at follow-up. Do not change or stop therapy without speaking with your healthcare professional.
Who should avoid this treatment?
Do not use if you have liver impairment or if you take strong or moderate CYP3A4 inhibitors. It is not approved for men or for postmenopausal adults. Avoid alcohol near dosing due to risks of low blood pressure and fainting. Provide your clinician with a complete list of medicines and supplements before starting.
What are common side effects?
Common effects include dizziness, sleepiness, nausea, fatigue, dry mouth, and trouble sleeping. Serious risks involve low blood pressure and fainting, particularly with alcohol or interacting medicines. Avoid driving or operating machinery until at least six hours after dosing. Contact a healthcare professional if side effects are severe or persistent.
How should I store the tablets and handle travel?
Keep tablets in the original container at room temperature. Protect from moisture and keep out of reach of children and pets. For travel, bring enough for the entire trip plus a few extra doses. Carry a copy of your prescription. If crossing time zones, continue bedtime dosing using your destination’s local time.
Can other medicines affect sexual desire and this treatment’s use?
Yes. Some antidepressants and other medicines can affect libido or interact with flibanserin. Strong or moderate CYP3A4 inhibitors are not compatible. CYP3A4 inducers may reduce effectiveness. Share all medicines and supplements with your prescriber so they can assess benefits, risks, and potential adjustments.
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