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Acyclovir Tablets for Herpes Infections
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This antiviral helps manage herpes virus infections that affect the skin and nerves. It supports faster recovery when started early and can reduce future outbreaks with suppressive therapy. This page explains approved uses, dosing basics, safety, and how you can arrange US delivery from Canada with clear pricing, including options without insurance.
What Acyclovir Is and How It Works
Oral Acyclovir is an antiviral that targets herpes simplex and varicella zoster viruses. It becomes active inside infected cells and interferes with viral DNA replication. That action helps slow the virus, shorten symptom duration, and support healing. Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.
This medicine belongs to a group of Antivirals used for recurrent cold sores, genital herpes, shingles, and chickenpox. It does not eliminate the virus from the body. The treatment may lower the intensity of pain, burning, and tingling during episodes. For background on conditions it treats, see Herpes Simplex and this guide to care options, Herpes Treatment.
Who It’s For
This medicine is indicated for adults and eligible adolescents with herpes simplex infections, including genital and oral outbreaks, and for shingles caused by varicella zoster. It may also be used for chickenpox in certain cases, based on clinical judgment and guidelines. People with significant kidney disease, dehydration, or a history of neurologic reactions to antivirals should discuss risks with a clinician before starting therapy.
Those with known hypersensitivity to this drug or its components should avoid it. Pregnant or breastfeeding individuals should review the official label and consult a healthcare professional to weigh risks and benefits. People with frequent recurrences may be candidates for long-term suppression to reduce outbreak frequency.
Dosage and Usage
Use exactly as prescribed on your pharmacy label. Tablets are typically taken multiple times daily during active outbreaks. Suppressive therapy for frequent recurrences is often taken twice daily over an extended period. Starting treatment at the first sign of tingling, burning, or pain can help the course of symptoms. Swallow tablets with water and stay well hydrated unless your clinician advises otherwise.
For shingles, treatment is generally most helpful when started as early as possible after the rash begins. If using a topical product for cold sores, wash hands before and after each application and avoid contact with eyes. Do not share topical tubes to reduce the risk of spreading infections. When uncertain about instructions, refer to the official prescribing information or consult your clinician for clarification. For symptom education, see Herpes Symptoms.
Strengths and Forms
This treatment is available in several oral and topical presentations. Common tablet strengths include 200 mg, 400 mg, and 800 mg. A topical option is also available as a Zovirax Oint 5 formulation. Availability can vary by pharmacy and manufacturer.
Acyclovir 5% cream is typically used for cold sores on the lips or face when a clinician recommends a topical route. An oral suspension for patients who cannot swallow tablets may also be available through some pharmacies. Your prescription will specify the form and strength based on your diagnosis and health status.
Missed Dose and Timing
If you miss a dose, take it when you remember unless it is close to your next scheduled dose. If it is nearly time for the next dose, skip the missed dose and resume the regular schedule. Do not take two doses at once. For topical use, apply the next dose as soon as you remember and continue the usual timing. Consistency helps keep antiviral levels steady.
Storage and Travel Basics
Store tablets and creams at room temperature in a dry place, away from excess heat and moisture. Keep containers tightly closed and out of reach of children and pets. When traveling, keep your medicine in original labeled packaging and carry a copy of your prescription. Place the medication in your carry-on bag to avoid extreme temperatures. Our partners use temperature-controlled handling when required.
Do not freeze topical formulations, and avoid storing them in a hot car. Check expiration dates regularly and do not use products that are outdated or visibly damaged. For clinical context on conditions related to travel exposures, review Chickenpox vs Shingles.
Benefits
When started early, this antiviral can help shorten the duration of shingles or herpes outbreaks. Suppressive therapy may reduce the number of recurrences and lower the intensity of symptoms over time. Topical therapy can provide targeted support for cold sores. Consistent use can help limit spread by reducing active viral replication during episodes. It is not a cure, but it can support meaningful symptom control.
Side Effects and Safety
- Headache
- Nausea or vomiting
- Diarrhea or abdominal pain
- Dizziness or fatigue
- Topical burning, stinging, or itching at the application site
Serious reactions are uncommon but can include kidney problems, confusion or agitation, tremors, or allergic reactions with rash or swelling. People with reduced kidney function may need dose adjustments to reduce the risk of side effects. Stop the medicine and seek medical attention if you notice signs of a severe reaction, unusual drowsiness, markedly decreased urination, or persistent neurologic symptoms.
For eye-related concerns, such as corneal irritation or lesions, consult a specialist. Learn more about eye involvement at Ocular Herpes.
Drug Interactions and Cautions
Tell your clinician about all medicines and supplements you use. Interactions may occur with drugs that affect kidney function, such as certain diuretics or NSAIDs at high doses, and with agents like probenecid or cimetidine that can alter antiviral levels. Using this treatment with other nephrotoxic medicines may increase risk of kidney problems. Alcohol can worsen dehydration, which is not ideal during treatment.
Older adults and those with chronic kidney disease may be more sensitive to side effects. Stay hydrated unless you have a medical reason to limit fluids. Report persistent headache, confusion, hallucinations, or severe nausea. Review the label before combining with other topical agents on the same area.
What to Expect Over Time
With early treatment, symptoms often begin to ease after the first few days. Healing continues as viral activity decreases. For people on suppressive therapy, fewer outbreaks may occur with steady use, though individual results vary. Taking doses on schedule, starting therapy at the first sign of symptoms, and maintaining hydration can support better outcomes under your clinician’s guidance.
If outbreaks remain frequent or severe, your prescriber may reassess the plan. For cold sores and genital herpes information, see Cold Sores and Genital Herpes.
Compare With Alternatives
Some patients use valacyclovir, a related antiviral that converts to acyclovir in the body. It offers alternative dosing schedules that some find convenient. See Valacyclovir for details. A branded option is also available; review Valtrex with your prescriber. Topical formulations like Zovirax ointment can be paired with oral therapy when indicated for cold sores.
Pricing and Access
We aim to make care affordable by offering Canadian pricing with transparent fees. You can review Acyclovir price alongside available pack sizes before you add to cart. If you pay cash, we also display Acyclovir price without insurance to help you plan. This service Ships from Canada to US, and your order is fulfilled by licensed partner pharmacies following prescription verification.
Want updates on seasonal deals and education resources. See our current offers at Promotions. For shingles and other conditions supported by this therapy, browse Shingles for additional context on care.
Availability and Substitutions
Stock can vary by strength and form. If a requested option is unavailable, your prescriber may recommend an alternative strength, a topical formulation, or a related antiviral. Pharmacists can coordinate with your clinician to adjust to a comparable therapy when appropriate. We do not promise restock dates, but alternatives are often suitable.
Patient Suitability and Cost-Saving Tips
This antiviral may suit adults with episodic or frequent herpes outbreaks, or those with shingles who can start early. It may be less suitable if you have severe kidney disease without dose adjustments, a history of allergic reactions to similar medicines, or uncontrolled dehydration. Always share your full medication list with your clinician, including supplements.
To save on costs, consider a multi-month supply when appropriate, since fewer refills can lower fees over time. Set refill reminders so you do not run out before planned trips or foreseeable triggers. If paying cash, you can review Acyclovir cash price and compare available manufacturers. Ask your prescriber whether a topical add-on could reduce local symptoms during the first days of an episode.
Questions to Ask Your Clinician
- Right timing to start therapy for my symptoms
- Whether episodic or suppressive treatment fits my history
- How kidney function affects dose and monitoring
- Ways to reduce triggers and lower recurrence risk
- Safe use with my current medicines and supplements
- Whether a topical option should be added for cold sores
- What to do if I miss multiple doses during an outbreak
Authoritative Sources
FDA DailyMed: Acyclovir Prescribing Information
Health Canada Drug Product Database
GSK (Zovirax brand information)
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Does Acyclovir cure herpes
No. Acyclovir manages infections caused by herpes viruses, but it does not eradicate them from the body. When started early during an outbreak, it can shorten symptom duration and help lesions heal. Suppressive therapy may reduce the number of recurrences over time. Safe sex practices and avoiding direct contact with active lesions can further lower the risk of transmission. Discuss goals of care and realistic expectations with your clinician.
How quickly does Acyclovir start to work
Many people notice symptom relief within a few days, especially when therapy begins at the first sign of tingling, burning, or pain. Response varies by person, outbreak severity, and timing. Consistent dosing as prescribed and hydration can support better outcomes. If symptoms persist or worsen, contact a healthcare professional to review your regimen and rule out complications.
Can I drink alcohol while taking Acyclovir
Alcohol does not directly interact with Acyclovir, but it can worsen dehydration and may increase the chance of headache or dizziness for some people. Staying well hydrated is recommended during antiviral therapy unless a clinician advises fluid restriction. If alcohol triggers outbreaks or interferes with adherence, consider limiting intake while you are on treatment.
Is Acyclovir safe during pregnancy or breastfeeding
Safety depends on individual factors. Acyclovir has been used during pregnancy and breastfeeding under clinical supervision, but decisions should be individualized. Your prescriber will consider the timing of therapy, outbreak severity, and available alternatives. Always review the official label and discuss potential risks and benefits before starting or continuing this medicine during pregnancy or lactation.
What if I have kidney disease
People with reduced kidney function may require dosing adjustments and closer monitoring. Tell your clinician about your latest kidney tests and all medicines you take, including over-the-counter products and supplements. Staying hydrated is important unless you are on a fluid restriction. Seek medical attention if you notice markedly decreased urination, swelling, or persistent confusion while on therapy.
Is topical Acyclovir the same as oral therapy
Topical products are intended for cold sores on the skin and provide localized support. Oral therapy circulates systemically and is used for broader indications, including genital herpes and shingles. Your clinician will choose the form based on the site and severity of infection, your medical history, and practical factors like adherence. Do not use topical products in the eye or inside the mouth unless directed.
Can children use Acyclovir
Pediatric use depends on age, weight, and the specific diagnosis. Clinicians may prescribe it for some conditions, such as certain cases of chickenpox or herpes infections, following established guidelines. Dosing is individualized, and caregivers should follow the label exactly. Store all medicines out of reach of children, and consult a pediatric clinician for dosing and safety questions.
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