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Amiodarone

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Uses of Amiodarone

Amiodarone affects the rhythm of your heartbeats. It is used to help keep the heart beating normally in people with life-threatening heart rhythm disorders of the ventricles (the lower chambers of the heart that allow blood to flow out of the heart).

Amiodarone is used to treat ventricular tachycardia or ventricular fibrillation.

Amiodarone is for use only in treating life-threatening heart rhythm disorders.

Precautions and Warnings

Amiodarone can cause dangerous side effects on your heart, liver, lungs, or vision.

You should not take this medicine if you are allergic to amiodarone or iodine, or if you have heart block, a history of slow heartbeats that have caused you to faint, or if your heart cannot pump blood properly.

Call your doctor or get medical help at once if you have: chest pain, fast or pounding heartbeats, trouble breathing, vision problems, upper stomach pain, vomiting, dark urine, jaundice (yellowing of the skin or eyes), or if you cough up blood.

Tell your doctor if you have signs of a thyroid problem, such as weight changes, extreme tiredness, dry skin, thinning hair, feeling too hot or too cold, irregular menstrual periods, or swelling in your neck (goiter).

You should not use amiodarone if you have:

  • a serious heart condition called “AV block” (2nd or 3rd degree), unless you have a pacemaker;
  • a history of slow heartbeats that have caused you to faint; or
  • if your heart cannot pump blood properly.

Amiodarone can cause dangerous side effects on your heart, liver, lungs, or thyroid.

To make sure this medicine is safe for you, tell your doctor if you have ever had:

  • asthma or another lung disorder;
  • liver disease;
  • a thyroid disorder;
  • vision problems;
  • high or low blood pressure;
  • an electrolyte imbalance (such as low levels of potassium or magnesium in your blood); or
  • if you have a pacemaker or defibrillator implanted in your chest.

Taking amiodarone during pregnancy may harm an unborn baby, or cause thyroid problems or abnormal heartbeats in the baby after it is born. Amiodarone may also affect the child’s growth or development (speech, movement, academic skills) later in life. Tell your doctor if you are pregnant or if you become pregnant.

You should not breast-feed while taking this medicine, and for several months after stopping. Amiodarone takes a long time to clear from your body. Talk to your doctor about the best way to feed your baby during this time.

Dosage

The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For ventricular arrhythmias:

  • Adults—At first, 800 to 1600 milligrams (mg) per day taken in divided doses. Your doctor may adjust your dose as needed and tolerated.
  • Children—Use and dose must be determined by your doctor.

Side Effects:

More Common Side Effects:

  • Cough
  • dizziness, lightheadedness, or fainting
  • fever (slight)
  • numbness or tingling in the fingers or toes
  • painful breathing
  • sensitivity of the skin to sunlight
  • trembling or shaking of the hands
  • trouble with walking
  • unusual and uncontrolled movements of the body
  • weakness of the arms or legs

Less Common Side Effects:

  • Blue-gray coloring of the skin on the face, neck, and arms
  • blurred vision or blue-green halos seen around objects
  • coldness
  • dry eyes
  • dry, puffy skin
  • fast or irregular heartbeat
  • nervousness
  • pain and swelling in the scrotum
  • sensitivity of the eyes to light
  • sensitivity to heat
  • slow heartbeat
  • sweating
  • swelling of the feet or lower legs
  • trouble with sleeping
  • unusual tiredness
  • weight gain or loss

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