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Cardalis® Tablets for Dogs with Heart Failure
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What Cardalis Is and How It Works
Cardalis is a veterinary prescription tablet used for dogs with heart failure due to degenerative mitral valve disease. It combines benazepril, an ACE inhibitor, with spironolactone, a potassium-sparing diuretic. This page explains how the treatment works, how to use it safely, and how to access US delivery from Canada, including options for cardalis without insurance.
Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.
Cardalis® lowers the workload on the heart and helps reduce fluid buildup. Benazepril decreases harmful hormonal activity in congestive heart failure. Spironolactone counters sodium and water retention while helping maintain potassium levels. Together, the medicines support easier breathing and improved comfort for many canine patients under a veterinarian’s care.
If your dog is starting therapy, your prescriber may recommend baseline kidney function and electrolytes, then periodic rechecks. Monitoring helps guide safe use. Always follow the veterinary label and your clinician’s instructions for this medicine.
Who It’s For
This therapy is for dogs with congestive heart failure caused by atrioventricular valve disease, especially degenerative mitral valve disease. It may be used along with other cardiac medicines such as diuretics or inodilators when directed by a veterinarian. Many adult dogs with chronic coughing, exercise intolerance, or fluid retention may be considered if diagnosed with structural heart disease.
Use benazepril spironolactone tablets for dogs only under veterinary supervision. Avoid use in dogs with known hypersensitivity to either component. Dogs with severe kidney disease, high potassium, dehydration, or low blood pressure need careful assessment before starting. Breeding, pregnant, or nursing dogs generally should not receive this combination unless a prescriber determines benefits outweigh risks.
If your dog has Addison’s disease, significant dehydration, or is on potassium supplements, additional caution is needed due to potassium changes. Report fainting, profound lethargy, or sudden appetite loss promptly.
Dosage and Usage
Veterinarians prescribe a dose based on your dog’s weight and clinical status. Your clinician may direct once-daily dosing in most cases. Offer the tablet with food if stomach upset occurs. Provide fresh water at all times. If your prescriber adds a loop diuretic or other cardiac therapy, follow their schedule carefully.
Use benazepril spironolactone 2.5mg/20mg for dogs or another strength only as written on the label. Do not change the dose on your own. If your dog vomits a dose shortly after administration, contact the clinic for guidance. Keep a simple log of doses given, appetite, breathing comfort, and activity level to share during follow-ups.
Do not split or crush the tablet unless your veterinarian specifically instructs. Wash hands after handling. Keep the medicine away from children and other pets.
Strengths and Forms
This medicine is supplied as oral tablets in multiple strengths for body-weight–based dosing. Availability may vary.
- cardalis 2.5mg/20mg tablets
- 5mg/40mg tablets
- 10mg/80mg tablets
Your prescriber will choose the appropriate strength based on weight and response. Never substitute another strength without veterinary direction.
Missed Dose and Timing
If you miss a dose, give it when you remember unless it is almost time for the next one. If it is close to the next scheduled dose, skip the missed dose and resume the regular schedule. Do not double up. If your dog misses more than one dose, contact the clinic for advice on restarting safely. Keep daily routines consistent to help adherence.
Space doses evenly each day when possible. Use a reminder on your phone or a weekly pill organizer labeled for pets to simplify tracking.
Storage and Travel Basics
Store tablets in the original container, tightly closed, and protected from moisture. Keep at room temperature and out of reach of children and animals. Do not store in the bathroom where humidity fluctuates. Dispose of expired tablets according to local guidance; do not flush unless instructed.
When you travel with your dog, keep the medicine in your carry-on along with the prescription label. Pack enough tablets for the trip and a few extra in case plans change. If your journey involves large temperature swings, protect the package from heat. Use a small insulated pouch if your veterinarian advises. For any sensitive therapies, we use temperature-controlled handling when required.
Pen Handling and Sharps Disposal
Not applicable. This product is an oral tablet and does not require injection supplies or sharps disposal.
Benefits
This combination therapy targets two mechanisms that drive fluid retention and cardiac workload. By tempering the renin-angiotensin-aldosterone system, the treatment can help reduce cough related to pulmonary congestion and ease breathing effort. Many dogs show better energy levels and improved comfort when therapy is optimized by their prescriber. Once-daily dosing simplifies routines for caregivers.
The tablet form makes administration straightforward for most dogs. Your clinician may pair this medicine with other cardiac therapies to match your dog’s condition.
Side Effects and Safety
- Common: reduced appetite, vomiting, diarrhea
- Sometimes: lethargy, dehydration, increased thirst or urination
- Lab changes: elevated potassium, kidney value shifts
Serious reactions are uncommon but can occur. Signs such as collapse, severe weakness, swollen abdomen, or persistent vomiting need urgent veterinary attention. Dogs with kidney disease or those receiving potassium supplements require close monitoring. Combining with NSAIDs can increase kidney risk in susceptible dogs; your prescriber may limit or avoid this combination.
Always disclose all medicines, vitamins, and treats with added electrolytes. Using benazepril spironolactone tablets for dogs alongside other diuretics or ACE inhibitors can raise the chance of low blood pressure or electrolyte changes.
Drug Interactions and Cautions
Tell your veterinarian about all therapies your dog receives. Potential interactions include potassium supplements, other potassium-sparing diuretics, ACE inhibitors, ARBs, certain NSAIDs, and some heart medicines. Your prescriber may adjust therapy or increase monitoring if combinations are needed. Use caution in dogs with kidney disease, dehydration, or low blood pressure. Avoid use during pregnancy or nursing unless specifically recommended by the prescriber.
Regular lab checks for kidney function and potassium help support safe, ongoing therapy. Report noticeable behavior changes, appetite loss, or worsening cough promptly.
What to Expect Over Time
Many dogs show gradual improvement in breathing comfort, activity tolerance, and nighttime rest as the plan is optimized. Some dogs may continue to cough, especially with excitement, but the overall pattern may ease. Your clinician will adjust companion therapies like loop diuretics or inodilators if needed. Expect periodic rechecks, including weight, respiratory rate, and blood work.
Consistency with dosing, diet, and salt intake supports stability. Keep a simple diary of resting breathing rate and daily energy. Share this during follow-ups so your prescriber can tailor therapy safely.
Compare With Alternatives
Veterinarians may consider other cardiac approaches depending on diagnosis and tolerance. ACE inhibitor monotherapy or inodilators can be used in different situations. Educational reading on related options is available in Enalapril For Dogs and What Is Benazepril. For heartworm prevention that supports heart health in a different way, see Proheart 6 or Heartgard. These are not direct substitutes for the treatment here; your veterinarian will guide choices.
Pricing and Access
We offer cardalis canadian pricing with US shipping from Canada. You can view current options, verify your prescription, and choose a refill plan that fits your needs. If you are exploring savings, check our promotions page for any available offers. Checkout is secure with encrypted processing, and our team confirms veterinary details before fulfilment.
For condition-specific browsing, visit Heart Failure or explore broader options under Cardiovascular. You can also review clinic-friendly tips in Online Prescriptions and ACE inhibitor overviews like Captopril Uses. For origin details, see Canada.
Availability and Substitutions
Stock can vary by strength. If a preferred tablet is not available, your prescriber may select another strength or an alternative regimen suited to body weight and lab results. We cannot provide specific restock dates. Your veterinarian’s guidance should determine any change.
Patient Suitability and Cost-Saving Tips
Good candidates include dogs with confirmed degenerative mitral valve disease and signs of fluid retention or heart enlargement. Dogs with severe kidney impairment, high potassium, or pregnancy are generally not suitable. If your dog is on multiple medicines, your prescriber will balance benefits and risks carefully.
To save, discuss multi-month quantities if appropriate. Align refills with scheduled rechecks to reduce extra visits. Set refill reminders on your phone. Keep a consistent pharmacy profile so your prescriber’s directions are clear. Ask your clinic whether home monitoring of resting respiratory rate can reduce extra trips while still ensuring safety.
Questions to Ask Your Clinician
- Ideal dose and timing for my dog
- Which lab tests and how often
- How to recognize fluid buildup early
- When to add or adjust other therapies
- Diet and salt guidance for heart health
- What side effects need urgent care
Authoritative Sources
Learn more from official references:
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What conditions is this tablet used for in dogs?
Veterinarians prescribe this combination of an ACE inhibitor and a potassium-sparing diuretic for dogs with congestive heart failure due to degenerative mitral valve disease. It lowers neurohormonal activity and helps reduce fluid buildup. Your clinician may pair it with other therapies like loop diuretics or inodilators based on exam findings. Use only under veterinary supervision and follow the label directions closely for your dog’s safety.
How quickly might my dog show improvement?
Some dogs show gradual improvements in breathing comfort and activity as the plan is adjusted by the veterinarian. Timing varies with disease stage, other medicines, and monitoring of kidney function and electrolytes. Your clinician may recommend tracking resting respiratory rate and appetite daily. Share updates during rechecks so the plan can be tailored. Avoid changing any dose without veterinary guidance.
Can I give this with other heart medicines?
Many dogs with heart failure receive combination therapy. Your veterinarian may use a loop diuretic, an inodilator, or other agents along with this prescription. However, combinations can increase risks such as low blood pressure or electrolyte changes. Provide a full list of all medicines and supplements. Your clinician will decide on compatible options and monitoring needs for your dog.
What side effects should I watch for?
Common effects include decreased appetite, vomiting, diarrhea, and occasional lethargy. Lab monitoring may show changes in kidney values or potassium. Contact your veterinarian immediately for collapse, profound weakness, persistent vomiting, or swollen abdomen. Dogs with kidney problems or those taking NSAIDs, potassium supplements, or other diuretics may need closer oversight to reduce risks.
What if my dog misses a dose?
If you miss a dose, give it when remembered unless it is near the next scheduled time. If it is close, skip the missed dose and resume the usual schedule. Do not give two doses at once. If multiple doses are missed, ask your clinic how to restart safely. A pill organizer and phone reminders can help maintain a consistent routine for your dog.
How should I store the tablets?
Keep tablets in the original container, tightly closed, dry, and at room temperature. Store out of reach of children and animals. When traveling, keep the prescription-labeled container in your carry-on and pack enough for the full trip. Protect from heat and moisture. Dispose of expired tablets according to local guidance; your clinic or pharmacist can advise on safe disposal options.
Do I need a prescription for this medicine?
Yes. This is a veterinary prescription treatment. A veterinarian must diagnose the condition and determine whether it is appropriate for your dog. Prescriptions are verified with the clinic before dispensing. Regular follow-up visits and lab monitoring may be recommended to help maintain safety and effectiveness over time.
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