Intuniv® XR Tablets for ADHD

Intuniv XR is a once-daily, extended-release form of guanfacine used for attention-deficit/hyperactivity disorder. It helps improve attention and reduce impulsivity in eligible patients. Border Free Health provides US shipping from Canada, and you can review options without insurance.

What Intuniv Is and How It Works

Attention Deficit and related symptoms are treated with non-stimulant options as well as stimulants. Intuniv® is guanfacine extended-release, a central alpha-2A adrenergic receptor agonist. It targets receptors in the prefrontal cortex, which may strengthen working memory and reduce distractibility. The treatment can be used alone or with a stimulant when a prescriber considers combination therapy appropriate. Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

Its mechanism reduces sympathetic nerve activity, which can lower heart rate and blood pressure. Sedation may occur, especially when starting or increasing the dose. Avoid alcohol and other sedatives because combined effects can increase drowsiness.

Who It’s For

This medicine is indicated for ADHD in children and adolescents 6 to 17 years of age. Some clinicians may consider careful use in adults when benefits outweigh risks, but labeling focuses on pediatric patients. When discussing options, questions about Hyperactivity Disorder and non-stimulant choices are common. People with a history of hypersensitivity to guanfacine should avoid it. Those with low blood pressure, heart block, bradycardia, or fainting tendencies need caution and monitoring. Pregnancy and lactation decisions require a prescriber’s guidance. Be cautious with activities needing alertness until individual response is clear. For clarity on off-label considerations, some patients might ask about Intuniv XR for adults, but decisions should remain individualized.

Dosage and Usage

This is a high-level overview; always follow your prescriber and the official label. The medicine is taken once daily, in the morning or evening, at the same time each day. Swallow tablets whole with water. Do not cut, crush, or chew. A high-fat meal can raise guanfacine exposure, so avoid taking doses with very fatty foods. Grapefruit and grapefruit juice can interact and may increase levels.

Titration is typically gradual. Prescribers may start low and increase stepwise to balance symptom control with tolerability. Do not stop abruptly; tapering helps reduce the risk of rebound effects. When switching from immediate-release guanfacine, note that the formulations are not milligram-for-milligram substitutes. For detailed schedules, refer to the Intuniv XR dosage guide in the official labeling.

Strengths and Forms

Extended-release tablets are supplied for once-daily administration. Common presentations include strengths ranging from 1 mg to 4 mg. Availability can vary by supplier and market.

Missed Dose and Timing

If a dose is missed, take the next dose at the usual time the following day. Do not double up. If two or more doses are missed, consult the prescriber; re-titration may be considered to limit side effects. Taking doses consistently, with similar meal patterns, can help minimize variability in effects.

Storage and Travel Basics

Store tablets at room temperature in a dry place away from excess heat and moisture. Keep the bottle tightly closed and out of reach of children and pets. For travel, keep the medication in its original labeled container and carry a copy of your prescription. Pack enough supply plus a small buffer, and place it in your carry-on. When crossing time zones, keep daily dosing intervals as consistent as possible. If questions arise, your clinician or pharmacist can advise. For transported items, Border Free Health supports temperature-controlled handling when required.

Benefits

This non-stimulant option may help reduce hyperactivity, improve attention, and support impulse control. Once-daily dosing can simplify routines. It can be used as monotherapy or as adjunctive therapy with a stimulant when a prescriber considers that approach appropriate. Nighttime dosing may be considered to limit daytime sleepiness, depending on individual response. For broader mental health topics, see Mental Health resources on our site.

Side Effects and Safety

People often search for Intuniv XR side effects to understand what to discuss with a prescriber. Common effects can include:

• Sleepiness or fatigue
• Dizziness or lightheadedness
• Headache
• Dry mouth
• Constipation or abdominal discomfort
• Nausea
• Decreased appetite

Serious effects are less common but can include low blood pressure, slow heart rate, fainting, and withdrawal symptoms with abrupt discontinuation. Seek urgent care for signs of allergic reaction like rash, swelling, or trouble breathing. Because this therapy can cause drowsiness, use caution with driving or operating machinery until you know how it affects you.

Drug Interactions and Cautions

Strong CYP3A4 inhibitors (such as certain azoles or macrolides) can increase guanfacine levels; inducers (such as some anticonvulsants) can lower them. Alcohol, benzodiazepines, opioids, and other sedatives can intensify drowsiness. Antihypertensives may add to blood-pressure lowering. Avoid grapefruit products. Combining stimulants and alpha-2 agonists is sometimes used clinically; discussions about Focalin XR and Intuniv together should be guided by a prescriber. People with significant cardiac disease, syncope history, or autonomic dysfunction may need careful monitoring.

What to Expect Over Time

Initial sleepiness or fatigue may occur as the body adjusts. Benefits often build gradually as dosing is optimized. Some patients notice improvements in routines and classroom or work tasks, while others may need dose adjustments or timing changes. Keeping a symptom and side effect log can help your healthcare professional tailor therapy. Adherence supports steady exposure and more predictable effects.

Compare With Alternatives

Many patients ask about non-stimulant and stimulant options. Guanficine ER vs Intuniv XR is a common comparison; they contain the same active ingredient, but brand and generic products can differ in appearance and inactive components. Other non-stimulant choices include clonidine ER or atomoxetine. Stimulants may be considered when appropriate. One option is Lisdexamfetamine; a prescriber can advise whether a stimulant, a non-stimulant, or a combination is suitable.

Pricing and Access

We aim to make Canadian pricing straightforward for U.S. patients. This service Ships from Canada to US with prescription verification. If you are comparing affordability, you can review Guanficine XR price and see how brand and generic options differ. Some patients also search to Buy guanfacine extended-release when comparing non-stimulant options. For current offers, visit our Promotions page. Secure checkout is supported with encrypted processes.

Availability and Substitutions

Supply can vary. If a specific brand or strength is not available, your prescriber may recommend a therapeutically appropriate alternative. In some cases, generic guanfacine ER may be considered. You can also browse items tagged with Canada to review country-of-origin details.

Patient Suitability and Cost-Saving Tips

This therapy may suit patients who cannot tolerate stimulants or who need adjunctive support. It may not be appropriate for those with significant bradycardia, hypotension, advanced heart block, or known hypersensitivity to guanfacine. Discuss liver or kidney issues with your clinician. For savings, consider multi-month supplies if your prescriber agrees, which can reduce refill frequency. Set refill reminders so you never run short. Keep your dosing time consistent, and store tablets properly to prevent waste. You can also compare brand and generic options to see which aligns with your budget and clinical plan.

Questions to Ask Your Clinician

• Is a non-stimulant appropriate for my ADHD symptoms and history?
• Should I take the tablet in the morning or evening based on my routine?
• How will we monitor blood pressure and heart rate during treatment?
• What signs mean I should contact the clinic between visits?
• Could a stimulant be added, or should this be used alone?
• How should tapering work if we decide to discontinue?
• Which lifestyle habits support attention and reduce side effects?

Authoritative Sources

DailyMed Label | Health Canada DPD | Takeda Product Information

Order Intuniv XR with prompt, express shipping and US delivery from Canada. This information is educational and not a substitute for professional medical advice; always follow your prescriber’s directions.