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Invokana® Tablets for Type 2 Diabetes
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This SGLT2 inhibitor helps adults with type 2 diabetes manage blood sugar. Invokana® is available for US delivery from Canada through BorderFreeHealth. If you compare Invokana price without insurance, this page explains strengths, usage, and safety in clear terms.
What Invokana Is and How It Works
Invokana® contains canagliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor. It helps lower blood glucose by reducing sugar reabsorption in the kidneys, so more glucose leaves the body through urine. This mechanism can also lead to increased urination and fluid loss, so staying hydrated matters.
Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.
By supporting urinary glucose excretion, this medicine may improve A1C when used with diet and activity. Some people may also see modest weight reduction. Based on labeled indications, the treatment can help reduce the risk of major cardiovascular events in certain adults with diabetes and established cardiovascular disease, and it can slow kidney disease progression in appropriate patients.
Learn more about the condition and related options in our Type 2 Diabetes hub. For background on this class, see Sglt2 Inhibitors.
Who It’s For
This therapy is indicated for adults with type 2 diabetes to improve glycemic control, along with diet and exercise. It may also be used to reduce cardiovascular risk in certain patients with established cardiovascular disease, and to help protect kidney function in those with diabetic kidney disease as described in the label.
It is not approved for type 1 diabetes or for treating diabetic ketoacidosis. People with severe kidney impairment, dialysis, or a history of serious hypersensitivity to canagliflozin should not use it. Use caution if you have conditions that increase amputation risk, recurrent genital infections, or low blood pressure. Review the full label and discuss your history with a clinician.
For a broader view of therapies, browse the concise Diabetes Drugs List.
Dosage and Usage
Take this medicine by mouth once daily, preferably before the first meal. Your prescriber may start with a lower tablet strength and increase if appropriate, based on goals and kidney function. Always follow the directions on your prescription label.
Drink fluids regularly unless your clinician advises otherwise. Stand up slowly to reduce dizziness from volume depletion. If you use insulin or a sulfonylurea with this treatment, your clinician may monitor for hypoglycemia. When uncertain, defer to the official prescribing information.
If you also manage Insulin Resistance, your care team may tailor a multi-medicine plan.
Strengths and Forms
- Canagliflozin 100mg tablets film-coated
- 300 mg tablets, film-coated
Availability can vary by supplier and package size.
Missed Dose and Timing
If you miss a dose, take it when you remember the same day. If it is almost time for the next dose, skip the missed dose and resume your regular schedule. Do not take two doses at once. Keeping a daily routine and setting reminders can help maintain consistency.
Storage and Travel Basics
Store tablets at room temperature in a dry place. Keep them in the original container, tightly closed, and away from moisture. Do not store in the bathroom. Keep out of reach of children and pets.
When traveling, bring your prescription label and enough tablets for the entire trip, plus a few extra days. Use a small pill organizer only if you can keep it secure and labeled. If your journey includes climate extremes, carry medicines in a hand bag to avoid excess heat or freezing. Our partners use temperature-controlled handling when required.
Pen Handling and Sharps Disposal
No pen or injector is used with this therapy. No sharps disposal is required.
Benefits
- Once-daily tablet for convenience
- Helps lower A1C alongside diet and activity
- May support modest weight reduction
- Shown to reduce certain cardiovascular risks in eligible adults
- Helps slow kidney disease progression in appropriate patients
Real-world results vary. Continue routine monitoring and follow your clinician’s plan.
Side Effects and Safety
- Increased urination or thirst
- Genital yeast infections
- Urinary tract infections
- Nausea or constipation
- Dizziness or low blood pressure, especially when dehydrated
Serious effects can occur. These include diabetic ketoacidosis (even if blood glucose is not very high), severe urinary or genital infections including rare necrotizing fasciitis of the perineum, acute kidney injury, hyperkalemia, bone fractures, and an increased risk of lower-limb amputation in some patients. Hypoglycemia can occur when used with insulin or sulfonylureas. Stop the medicine and seek care if you have signs of ketoacidosis, severe pain, fever, or infection. Review the Medication Guide and talk with your prescriber about your risks.
Drug Interactions and Cautions
Tell your clinician about all medicines and supplements you use. Diuretics may increase dehydration risk. Some enzyme inducers, such as rifampin or phenytoin, can reduce exposure to canagliflozin. Digoxin levels may increase with concurrent use. Monitor if you take blood pressure medicines that can affect kidney function. Avoid taking this therapy during active ketoacidosis. Discuss foot care if you have peripheral vascular disease, neuropathy, or prior ulcers.
What to Expect Over Time
Glucose changes may build gradually with consistent daily use. Your clinician may track A1C, kidney function, and electrolytes, and assess symptoms like lightheadedness or increased urination. Staying hydrated, eating balanced meals, and maintaining activity can support your plan. Most people continue therapy long term if it remains safe and effective for their goals.
Compare With Alternatives
This treatment belongs to the SGLT2 inhibitor class. Other options in the class include empagliflozin and dapagliflozin; see our quick overview in Jardiance Vs Farxiga. If your prescriber prefers a different mechanism, a DPP-4 inhibitor may be considered. We offer Sitagliptin and Sitagliptin Malate, which work by enhancing incretin activity rather than promoting urinary glucose excretion.
Pricing and Access
Canadian pharmacy networks often provide competitive rates. Check current Invokana price and compare with Canagliflozin price to see which option suits your budget and plan. We show transparent details so you can decide and then share choices with your prescriber. For seasonal deals, see our Promotions page.
Ordering through BorderFreeHealth supports US delivery from Canada with clear checkout. We use secure encryption and verify prescriptions before dispensing. To browse related items, visit Diabetes Care and explore country-of-origin filters such as Canada for more context.
Availability and Substitutions
Supply can vary. If a specific strength or pack size is not available, your prescriber may recommend a clinically appropriate alternative. When suitable, generics may be an option; examples include Canagliflozin 300mg tablets. Final product selection depends on your prescription and clinical needs.
Patient Suitability and Cost-Saving Tips
Good candidates are adults with type 2 diabetes who need additional glucose control despite diet and exercise, and who have adequate kidney function for this class. Those with recurrent complicated infections, active foot ulcers, or severe dehydration risk may need different strategies. If you track Invokana cost out of pocket, consider these practical steps:
- Multi-month fills: Ask your prescriber about 60- or 90-day supplies
- Refill reminders: Set alerts to avoid missed doses and rush orders
- Plan for labs: Coordinate checkups to align with refill timing
- Compare options: Review brand and generic availability with your clinician
- Lifestyle support: Pair therapy with nutrition and activity guidance
Exploring adjunct therapies and supportive resources can help. Visit our Weight Management section if your clinician includes weight goals in your plan, and see timely education such as National Diabetes Month updates.
Questions to Ask Your Clinician
- Is this SGLT2 therapy appropriate for my kidney function and goals?
- How should I track glucose, blood pressure, and hydration while using it?
- Which signs of infection, ketoacidosis, or dehydration need urgent care?
- Could a DPP-4 inhibitor or another class be a better fit for me?
- How will other medicines I take affect benefits or risks?
- What foot care steps should I follow to lower amputation risk?
- When should we reassess therapy and lab work?
Authoritative Sources
FDA DailyMed Prescribing Information
Janssen Official Prescribing Information
Health Canada Drug Product Database
Ready to proceed? You can start your order for US delivery from Canada with prompt, express shipping. This information is educational and not a substitute for professional medical advice. Always follow your clinician’s guidance.
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What is Invokana used for?
Invokana (canagliflozin) is an oral medication used to manage blood sugar levels in adults with type 2 diabetes. It belongs to the class of drugs known as sodium-glucose cotransporter 2 (SGLT2) inhibitors. In addition to improving glycemic control, Invokana has been shown to provide cardiovascular and kidney protective benefits in high-risk patients. It is not recommended for the treatment of type 1 diabetes or diabetic ketoacidosis.
How does Invokana help control blood sugar?
Invokana blocks the SGLT2 protein in the kidneys, which typically reabsorbs glucose into the bloodstream. By inhibiting this protein, more glucose is excreted through urine, lowering blood sugar levels. This mechanism is independent of insulin, making it useful in various stages of diabetes. Additionally, it may promote modest weight loss and lower blood pressure in some patients.
How should I take Invokana?
Invokana is typically taken once daily before the first meal of the day. It should be swallowed whole with water. Dosage may vary based on kidney function, other medications, and individual response, so following your doctor’s instructions is essential. Your doctor may adjust the dose based on your blood sugar levels and kidney performance.
What precautions should I take while on Invokana?
Invokana may increase the risk of urinary tract infections, genital yeast infections, and dehydration, especially in older adults. There is also a rare but serious risk of diabetic ketoacidosis (DKA), even in people with normal blood sugar levels. It may cause a drop in blood pressure, so individuals taking blood pressure medications should be monitored closely. Patients with kidney disease may require dose adjustments or may not be eligible for treatment.
What are the common side effects of Invokana?
Common side effects include increased urination, thirst, and risk of genital fungal infections. Other possible effects are fatigue, low blood pressure, and changes in kidney function. In rare cases, it may lead to bone fractures or serious urinary tract infections. Report any unusual symptoms such as abdominal pain, nausea, or confusion promptly to your healthcare provider.
How does this SGLT2 medicine lower blood sugar?
It blocks the SGLT2 transporter in the kidneys, which reduces glucose reabsorption and increases glucose excretion in urine. This helps lower blood sugar when used with diet and activity. Because the effect increases urination, hydration is important. Your prescriber may monitor kidney function, blood pressure, and A1C to ensure the treatment remains appropriate over time.
Who should avoid starting this treatment?
People with severe kidney disease, those on dialysis, or anyone with a known serious allergy to canagliflozin should not use it. It is not for type 1 diabetes or for treating diabetic ketoacidosis. Caution is advised in patients with low blood pressure, frequent genital or urinary infections, foot ulcers, or peripheral vascular disease. Discuss your full medical history with your clinician before starting.
Can it cause low blood sugar by itself?
On its own, this class has a low risk of hypoglycemia. However, the risk increases when combined with insulin or sulfonylureas. Your clinician may recommend closer glucose monitoring and may adjust other parts of your plan if needed. Watch for symptoms like shakiness, sweating, or confusion, and follow your prescribed rescue steps if they occur.
What side effects should I watch for?
Common effects include urination more often, thirst, genital yeast infections, and sometimes urinary tract infections, nausea, or constipation. Serious but less common risks include ketoacidosis, severe urinary or genital infections (including rare necrotizing fasciitis of the perineum), acute kidney injury, hyperkalemia, fractures, and increased risk of lower-limb amputation in some patients. Seek medical care if you have severe pain, fever, or signs of infection.
How should I take it each day?
Take one tablet by mouth once daily, preferably before the first meal. Try to take it at the same time each day. If you miss a dose, take it when you remember the same day, or skip if it is close to the next scheduled dose. Do not double up. Follow the directions on your prescription label and speak with your healthcare professional about any questions.
What happens if my kidneys are not working well?
Effectiveness and safety depend on kidney function. If your kidney function is reduced, your clinician will consider whether this therapy is appropriate. People with severely impaired kidney function or on dialysis should not use it. Periodic lab tests help determine if benefits continue to outweigh risks. Always follow the official label and your prescriber’s guidance.
Can I use this during surgery or acute illness?
During serious illness, surgery, or times of reduced food or fluid intake, your clinician may advise steps to reduce the risk of ketoacidosis or dehydration. This can include temporarily stopping certain medicines in this class before a procedure. Make a plan with your healthcare professional in advance, and follow their instructions based on the current label and your health status.
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