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Kaletra® Oral Solution for HIV
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Kaletra Oral Solution is a prescription antiretroviral used with other HIV medicines. It combines lopinavir with ritonavir to help control HIV-1. You can request Kaletra Oral Solution without insurance, with US delivery from Canada.
What Kaletra Is and How It Works
Kaletra® contains two protease inhibitors. Lopinavir blocks the HIV-1 protease enzyme. Ritonavir slows the breakdown of lopinavir to raise active levels. Together, they help lower viral load as part of a complete regimen for HIV. Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.
Lopinavir Ritonavir Oral Solution is usually taken with other antiretrovirals. It does not cure HIV. It can help reduce the amount of virus in the blood when taken exactly as prescribed. Your clinician may adjust the overall regimen based on drug interactions and treatment history.
This treatment has a liquid form that supports patients who cannot swallow tablets. It may be considered for adults or children who need flexible dosing. It should be used only under the supervision of a healthcare professional familiar with HIV care.
Who It’s For
This medicine is indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection. It is appropriate for adults and pediatric patients who can take an oral liquid. It is often used when a patient needs a liquid option or weight-based dosing.
People with severe liver impairment may not be candidates. The oral solution contains alcohol and propylene glycol. It should not be used in neonates younger than 14 days of age or in preterm infants before reaching a corrected postnatal age of 14 days. Patients with a history of pancreatitis, significant liver disease, or heart conduction problems need careful evaluation.
Women using hormonal contraceptives may need a non-hormonal method. Several medicines are contraindicated with this therapy due to serious interaction risks.
Dosage and Usage
Kaletra Oral Solution 80/20 mg/mL is measured with an accurate oral dosing device. Typical adult dosing follows the approved schedules for lopinavir/ritonavir, taken with food to improve tolerability. Pediatric dosing is weight-based and follows label-directed tables. Your prescriber will determine a regimen based on age, weight, other medicines, and your overall plan.
Use a marked oral syringe for each dose. Do not use household spoons. Take doses consistently at the same times each day. If your clinician gives an once-daily schedule, follow it exactly. Do not change dose or frequency on your own. Avoid alcohol use with this medicine. Review the full prescribing information for details on dosing in special situations, such as pregnancy or co-administration with certain agents.
Because this solution contains alcohol and propylene glycol, your clinician may provide additional instructions for children or those with hepatic impairment. If your regimen includes other medicines, ask about spacing and food requirements for each component.
Strengths and Forms
- Oral solution: 80 mg lopinavir / 20 mg ritonavir per mL
- Common package: 160 mL bottle
Availability may vary. Your prescription will specify the form and quantity that fits your regimen.
Missed Dose and Timing
If you miss a dose, take it as soon as you remember. If it is almost time for the next dose, skip the missed dose and resume your regular schedule. Do not take extra to make up for a missed dose. If vomiting occurs shortly after a dose, follow your clinician’s advice based on the timing and your plan. Keeping a daily reminder or using a pillbox with an oral syringe can help maintain steady adherence.
Storage and Travel Basics
Kaletra oral liquid should be kept as directed on the label. Refrigerate before dispensing when instructed. After dispensing, it can usually be stored in a refrigerator, or at room temperature for a limited period as described in the official labeling. Do not freeze. Keep the bottle tightly closed and away from open flames due to the alcohol content. Store out of reach of children and pets.
For travel, keep the bottle in your carry-on bag with the pharmacy label attached. Bring a copy of your prescription and your clinician’s contact details. Use a leak-proof bag for the dosing syringe. When crossing borders or going through security, present the labeled medicine if asked. If you need additional guidance on testing or care planning around travel, you can review our resource on Types Of HIV Tests and discuss your itinerary with your prescriber.
Benefits
This treatment is a protease inhibitor–based option taken with other antiretrovirals. It supports viral load reduction when used as directed. The liquid format offers flexible dosing for patients who cannot swallow tablets. It allows weight-based dosing in pediatric care when appropriate. Taking it with food may improve stomach tolerability for some people.
Side Effects and Safety
- Gastrointestinal: diarrhea, nausea, vomiting, abdominal pain
- General: fatigue, headache, taste changes
- Metabolic: increased triglycerides or cholesterol
- Liver-related: elevated liver enzymes
- Skin: rash
Serious effects can include pancreatitis, severe liver problems, heart rhythm changes such as PR interval prolongation, and severe skin reactions. Immune reconstitution syndrome can occur when starting combination therapy. High blood sugar has been reported with protease inhibitors. Seek urgent care for signs such as severe abdominal pain, jaundice, fainting, or widespread rash. Report new or worsening symptoms promptly to your clinician.
Drug Interactions and Cautions
This medicine strongly inhibits CYP3A and has many interactions. Contraindicated or restricted partners include certain sedatives (for example, triazolam, oral midazolam), ergot derivatives, some antiarrhythmics, and specific statins like simvastatin or lovastatin. Strong inducers such as rifampin can lower levels and reduce effectiveness. St. John’s wort should be avoided. Interactions can occur with anticoagulants, anticonvulsants, and many other agents.
Hormonal birth control effectiveness may decrease; consider a reliable non-hormonal method. The oral solution contains alcohol and propylene glycol, so avoid disulfiram and use caution with metronidazole. People with liver disease need close monitoring. Review the full Prescribing Information or DailyMed listing for the complete interaction tables, and inform your healthcare professional about all medicines and supplements.
To learn more about another protease inhibitor used in certain cases, see our Aptivus Overview. For background on newer regimens, explore our Biktarvy Guide.
What to Expect Over Time
With consistent dosing and a full antiretroviral regimen, many patients see viral load reductions on follow-up labs. The timetable varies by individual and co-morbid conditions. Some side effects can appear early, then improve. Ongoing monitoring by your clinician helps assess response, check lab values, and manage interactions. Do not stop therapy without medical guidance, even if you feel well. Keep regular appointments and follow the plan set by your care team.
Compare With Alternatives
Several approved antiretrovirals may be considered based on your history and resistance profile. A single-tablet option such as Delstrigo may suit stable adults without specific contraindications. If you can swallow tablets and your clinician prefers a pill form of the same active ingredients, Kaletra 200 50mg can be discussed. Each regimen has unique interaction and tolerability considerations. Your prescriber will match therapy to your needs and lab data.
Pricing and Access
We offer Canadian pricing with transparent checkout. If you are comparing options, you can review Kaletra Oral Solution price on the product page. Self-pay patients often ask about Kaletra Oral Solution cash price; amounts vary by supply and manufacturer sourcing. You can see current options before placing an order.
We provide US shipping from Canada for prescription orders and maintain encrypted checkout to protect your information. If you are looking for seasonal offers, visit our Promotions page. You can also explore condition pages like HIV and product families such as Antivirals. Sourcing details are listed on Canada Origin items.
Availability and Substitutions
Supply can change due to manufacturer cycles. If the oral solution is unavailable, a prescriber may recommend a comparable alternative based on your treatment plan. Your pharmacy team will contact your clinician for any substitution discussions. We do not quote restock dates, but we can notify you when an item returns to inventory.
Patient Suitability and Cost-Saving Tips
This treatment may be a fit for patients who need a liquid, who require weight-based dosing, or who have difficulty swallowing tablets. It may not suit people with severe hepatic impairment, young neonates, or those taking contraindicated medicines. Review your full medication list and medical history with your prescriber to confirm suitability.
To lower out-of-pocket spend, consider:
- Multi-month fills: fewer refills can reduce fees over time
- Aligned refills: synchronize with other approved medicines
- Set reminders: calendar alerts help maintain adherence
- Travel-ready plan: order early before long trips
- Talk to your prescriber: confirm the most efficient bottle size
If you want broader background on symptoms and care, see our article on HIV AIDS Symptoms. For public health updates and testing awareness, explore HIV Testing Day.
Questions to Ask Your Clinician
- Is this oral solution appropriate for my HIV regimen?
- How should I measure doses and take it with meals?
- Which medicines or supplements must I avoid?
- What lab monitoring will you order and how often?
- What signs mean I should call you right away?
- If I cannot tolerate the liquid, what are my alternatives?
- How should I plan around travel and refill timing?
Authoritative Sources
Ready to proceed? You can place your order today for prompt, express shipping with temperature-controlled handling when required. This page is educational and does not replace your clinician’s advice.
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Shipping Countries:
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- Worldwide (excludes some countries***)
How is the oral solution different from the tablets?
Both forms contain lopinavir and ritonavir. The liquid supports flexible dosing and can help when a person cannot swallow tablets or needs weight-based dosing. The solution has alcohol and propylene glycol, which affects storage, interactions, and pediatric use. Tablets do not contain alcohol. Your clinician will choose based on age, weight, interaction risks, and how you take medicines. If you can swallow pills and prefer fewer measuring steps, tablets may be considered instead.
Can children use this medicine safely?
Pediatric use is common with careful weight-based dosing by the prescriber. The oral solution contains alcohol and propylene glycol, so it is not for neonates younger than 14 days or preterm infants before corrected postnatal age of 14 days. Dosing, monitoring, and food instructions should follow the official label. Parents should use a calibrated oral syringe and keep the bottle out of children’s reach. Discuss growth, labs, and any side effects at each visit.
What foods or drinks should I avoid?
Take doses with food as directed to help tolerability. Because the solution contains alcohol and propylene glycol, avoid taking it with alcoholic drinks. Grapefruit and certain herbal supplements, such as St. John’s wort, can affect drug levels and should be avoided. If your regimen includes other medicines with specific food instructions, follow each product’s label. When in doubt, ask your healthcare professional to review your entire plan, including supplements and over-the-counter items.
What are the most common side effects?
The most reported effects include diarrhea, nausea, vomiting, abdominal discomfort, and headache. Some people notice changes in taste. Lab tests may show increased cholesterol or triglycerides, or elevated liver enzymes. Many effects are manageable and may improve with time. Serious reactions can occur, such as pancreatitis or liver problems. Report persistent or severe symptoms promptly and seek urgent care for severe abdominal pain, jaundice, fainting, or widespread rash.
How should I store the bottle at home?
Follow the label. Refrigerate as directed before dispensing. After dispensing, the solution can typically be kept in a refrigerator or at room temperature for a limited period per the official labeling; do not freeze. Keep the cap tightly closed and away from flames because it contains alcohol. Store out of reach of children and pets. If you travel, keep it in your carry-on, bring the prescription label, and pack a dosing syringe in a leak-proof bag.
Are there important drug interactions?
Yes. This medicine inhibits CYP3A and interacts with many drugs. Contraindicated partners include oral midazolam, triazolam, ergot derivatives, some antiarrhythmics, and specific statins like simvastatin or lovastatin. Rifampin and St. John’s wort can reduce levels. Interactions also occur with anticoagulants, anticonvulsants, and others. Hormonal contraceptives may be less effective. Provide your prescriber with a complete list of prescription drugs, OTC products, and supplements so they can verify safety.
What if I miss a dose or vomit after taking it?
If you miss a dose, take it when remembered unless it is close to the next scheduled time. Do not double up. If vomiting occurs soon after a dose, contact your prescriber for specific guidance, because advice can depend on the timing and your regimen. Keeping reminders and taking the medicine with food as directed can help reduce missed doses and stomach upset. Never change the dosing schedule on your own; always check the official label or your clinician’s instructions.
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