Myrbetriq® Extended-Release Tablets for Overactive Bladder

Myrbetriq® is a prescription beta-3 adrenergic agonist used for overactive bladder symptoms in adults. It helps reduce urgency, frequency, and urge incontinence by relaxing the bladder muscle. You can access this therapy with US delivery from Canada, including options for those paying without insurance.

What Myrbetriq Is and How It Works

Myrbetriq® contains mirabegron, which selectively stimulates beta-3 receptors in the bladder detrusor muscle. This action can increase bladder capacity and reduce involuntary contractions. It may be used alone or with an antimuscarinic when a clinician advises combination therapy.

Border Free Health connects U.S. patients with licensed Canadian partner pharmacies; prescriptions are verified with prescribers before dispensing.

Mirabegron ER tablets act on the bladder during the storage phase. Many people take this medicine once daily and swallow the tablet whole. It can be taken with or without food. Follow your prescriber’s directions and the official label for details.

For broader education on symptom patterns and causes, see our category guide for Overactive Bladder.

Who It’s For

This treatment is for adults with overactive bladder symptoms, including urgency, frequency, and urge leakage. It may be considered when behavioral strategies are not enough or when antimuscarinics are not tolerated. People with severe, uncontrolled hypertension should not use it. Those with significant bladder outlet obstruction, narrow-angle glaucoma risk, or certain heart rhythm concerns should discuss safety with a healthcare professional. If pregnant, trying to conceive, or breastfeeding, talk with your prescriber about risks and alternatives.

Some patients may use this medicine alongside lifestyle steps such as timed voiding and fluid adjustments. For condition context, review our page on Urinary Incontinence.

Dosage and Usage

The typical starting schedule for adults is once daily. Many start at a lower dose and may increase if tolerated and needed. Swallow tablets whole with water. Do not crush, split, or chew. You can take it with or without food at the same time each day.

If combining with an antimuscarinic, a prescriber may recommend a conservative plan and reassess tolerability. People with kidney or liver impairment often need careful dose selection. Always defer to the official label and your clinician’s guidance for individual adjustments and monitoring.

For additional background on practical use, see Dosage Forms.

Strengths and Forms

Extended-release tablets are commonly available in 25 mg and 50 mg. Availability may vary by supplier and country. Your prescriber will choose the dose that aligns with your health status and response. The extended-release design supports once-daily use.

Missed Dose and Timing

If you miss a dose, take it when you remember the same day. If it is nearly time for the next dose, skip the missed one and resume your regular schedule. Do not take two doses at once. Keeping a daily reminder can help maintain steady use.

Storage and Travel Basics

Store tablets at room temperature in a dry place. Keep the bottle tightly closed and out of children’s reach. Avoid bathrooms where humidity is high. When traveling, keep your medicine in its original labeled container, and carry a copy of your prescription. Pack it in your carry-on to reduce loss or temperature extremes. If you use a weekly pill organizer, ensure child-resistant storage at home.

Pharmacy handling follows standard quality procedures, with temperature-controlled handling when required by product type.

Benefits

This class can reduce urgency episodes, cut bathroom trips, and limit urge leakage. It may be an option for people who did not do well on antimuscarinics. Because it works by beta-3 activation, it may avoid some anticholinergic effects like dry mouth for many patients. It can also be combined with an antimuscarinic when a clinician judges that approach appropriate.

Side Effects and Safety

• Common: increased blood pressure, headache, nasopharyngitis, urinary tract infection
• Gastrointestinal: constipation, nausea, abdominal discomfort
• Cardiac: tachycardia or palpitations in some patients

Serious but less common reactions include angioedema, marked hypertension, and urinary retention. People at risk for retention, such as those with significant prostate enlargement or obstruction, should be monitored. Seek urgent care for swelling of the face, lips, tongue, or throat, or for severe allergic reactions. If you take insulin or sulfonylureas for diabetes, this medicine does not typically cause low blood sugar; however, overall health changes can affect how you feel. Contact a clinician if symptoms change suddenly.

For a deeper dive, read Side Effects To Know.

Drug Interactions and Cautions

Mirabegron can inhibit CYP2D6 and may raise levels of certain medicines, including metoprolol, desipramine, and flecainide. If you take a narrow therapeutic index drug metabolized by CYP2D6, your prescriber may monitor more closely. Mirabegron can also interact with P-glycoprotein substrates like digoxin; starting at a lower digoxin dose and checking levels can be considered by your clinician.

Use caution if you have hypertension. Do not use in severe, uncontrolled high blood pressure. Inform your clinician about liver or kidney issues, arrhythmias, or bladder outlet obstruction. Combining with antimuscarinics can increase the risk of urinary retention in some people. Always share a full medication list, including over-the-counter products and supplements.

What to Expect Over Time

Responses vary. Some people notice fewer urgent trips and improved control after consistent daily use. Others may need a dose change or an adjunct therapy recommended by their prescriber. Keep a symptom diary to track changes and triggers. If you do not see meaningful benefit after a reasonable trial, your clinician may consider alternatives or combination therapy. Adherence and routine follow-up help guide next steps.

Compare With Alternatives

Antimuscarinic therapies remain common options. Your clinician may consider a trial of Oxybutynin or Solifenacin Succinate if beta-3 therapy is not suitable or needs support. Choice depends on your health profile, other medicines, and tolerance to side effects. Review our broader Urology selection to explore more options with your prescriber.

Pricing and Access

Border Free Health lists transparent options and updates availability regularly. Check current Mirabegron price and compare quantities to plan your refill rhythm. We offer encrypted checkout and support for prescription verification. Ships from Canada to US for qualifying orders. See whether your benefit plan applies, or pay cash if you prefer.

If you are looking to switch or start, you can Order Myrbetriq from Canada through our platform once your prescription is on file. For seasonal offers, see our Promotions page. Always review savings details with your prescriber and insurer.

Availability and Substitutions

Stock can vary by strength and pack size. Generic options may be available in some markets under the name mirabegron. If your preferred item is unavailable, your prescriber may recommend a comparable antimuscarinic or combination approach. For country-of-origin specifics, view the attribute page for Canada. If you prefer a digital overview, see our learning piece on Treat OAB. You can also Buy mirabegron online through our site once your prescription is verified.

Patient Suitability and Cost-Saving Tips

This therapy may suit adults who experience urgency and frequency that affect daily routines. It can be useful when antimuscarinics cause side effects or do not provide adequate control. People with severe, uncontrolled hypertension should avoid it. Those with moderate to severe kidney or liver issues need individualized plans set by a prescriber.

To save on total costs, ask your clinician about a Myrbetriq 90-day supply to reduce pharmacy fees per fill. Set refill reminders so you do not miss doses. Combine therapy with bladder training and fluid timing if your clinician approves. Review formulary coverage and consider comparing quantities on the product page before you place your order.

Questions to Ask Your Clinician

• Right candidate: Is this the best first-line or add-on option for me?
• Dose plan: How should my dose be adjusted if I respond or have side effects?
• Combination: Would pairing with an antimuscarinic be helpful for my goals?
• Monitoring: What blood pressure checks or labs should I plan for?
• Interactions: Do my heart, mood, or seizure medicines require closer review?
• Expectations: What changes should I track in a bladder diary?

Authoritative Sources

• Astellas Pharma US
• FDA DailyMed: Mirabegron
• Health Canada Drug Product Database

Ready to proceed? Place your order today for US shipping from Canada with prompt, express shipping. This page is informational and not a substitute for medical advice; always follow your prescriber’s instructions and the official label.