Myrbetriq (mirabegron) Extended-Release Tablets

Myrbetriq is a prescription mirabegron tablet used to help manage overactive bladder symptoms such as urgency and frequent urination. This page explains how the medicine works, what to know about dosing basics, and the main safety points to review with a clinician. BorderFreeHealth supports cash-pay access, including for people without insurance, with US shipping from Canada after prescription review.

It can help when symptoms disrupt sleep, work, or daily routines. The sections below focus on practical, label-aligned information.

What Myrbetriq Is and How It Works

This medicine contains mirabegron, a beta-3 adrenergic agonist (a bladder-relaxing medicine). It works by helping the detrusor (bladder muscle) hold more urine without contracting as often. In plain terms, it targets “gotta go now” signals that can drive urgent bathroom trips. It is different from many older bladder medicines that block acetylcholine (often called anticholinergics), which can be associated with dry mouth or constipation.

Medicines are dispensed through licensed Canadian partner pharmacies. Mirabegron may be used alone or, in some cases, alongside other approaches that support bladder control. For a deeper look at the mechanism and symptom patterns, the guide How It Treats OAB explains how urgency and frequency can develop and how drug classes differ.

Who It’s For

Mirabegron is commonly prescribed for adults with overactive bladder (OAB), especially when symptoms include urinary urgency, increased daytime frequency, and urge urinary incontinence (leakage with urgency). These symptoms can overlap with other urinary conditions, so evaluation matters before starting a long-term therapy. If you are browsing by condition, the Overactive Bladder hub and the Urinary Incontinence hub group related options and background topics.

This treatment is not appropriate for everyone. Prescribers typically review blood pressure history, kidney and liver function, and whether there is bladder outlet obstruction (a blockage that can make it hard to empty the bladder). It may not be a fit for people with severe or uncontrolled hypertension, and it may require extra caution if there is a history of urinary retention. For broader navigation across urinary therapies, the Urology Category can help organize what is available.

Dosage and Usage

For many adults, Myrbetriq is taken once daily as an extended-release tablet. Prescribers often start with a lower strength and reassess symptoms and tolerability before considering changes. A common starting point in adults is 25 mg once daily, and some patients may be increased to 50 mg once daily if appropriate. Kidney or liver impairment can affect dosing decisions, so lab history is often part of the prescribing discussion.

Tablets are meant to be swallowed whole, not crushed, chewed, or split, because that can change how the extended-release form delivers medication. The medicine can be taken with or without food, and it helps to take it at a consistent time each day. If a dose is missed, the label instructions and a pharmacist’s guidance are the safest reference points. For practical, non-personalized reminders about routines and common questions, see Dosing Explained Tips and Dosage Forms Strengths.

Strengths and Forms

This product is supplied as a Mirabegron ER tablet (extended-release). The extended-release design is intended to release medicine over the day rather than all at once. Availability can differ by pharmacy partner and current sourcing, so it helps to confirm the exact presentation during checkout and verification.

Myrbetriq extended-release tablets are commonly dispensed in 25 mg and 50 mg strengths. You may see these described as Mirabegron 25 mg tablets and Mirabegron 50 mg tablets, which refer to the same active ingredient. These are typically taken once daily, as directed by the prescriber.

Storage and Travel Basics

Store tablets at room temperature and keep them protected from moisture. Keeping the medication in its original container can help preserve stability and reduces mix-ups with look-alike tablets. Bathrooms can be humid, so a bedroom drawer or a dry cabinet is often a better spot. Always store medicines out of reach of children and pets, even when a bottle has a child-resistant cap.

When traveling, carry the medication in a labeled container and keep a copy of the prescription information if possible. Avoid leaving tablets in a hot car or in freezing conditions, since extreme temperatures can affect many medicines. If you use a pill organizer, consider refilling it away from steam or sinks to limit moisture exposure.

Quick tip: Set a recurring reminder tied to a daily routine, like brushing teeth.

Side Effects and Safety

Many people take mirabegron without major problems, but side effects can occur. Commonly reported issues include increased blood pressure, headache, cold-like symptoms, and urinary tract infection (UTI) symptoms. Because this therapy can raise blood pressure in some individuals, monitoring may be recommended, especially when starting or changing the dose. If there is a history of hypertension, that context is important to share with the prescriber.

The pharmacy confirms prescriptions with prescribers before dispensing. Serious reactions are uncommon but require urgent attention if they happen. These can include allergic swelling (angioedema), fast or irregular heartbeat symptoms, or urinary retention (inability to empty the bladder), especially in people who already have obstruction or take other bladder medicines. Myrbetriq should be stopped and evaluated promptly if severe allergic symptoms occur. For a structured review of what is typical versus urgent, see Side Effects Overview.

Why it matters: Early recognition of urinary retention can prevent kidney strain and infection complications.

Drug Interactions and Cautions

Mirabegron can affect how certain medicines are metabolized because it inhibits CYP2D6 (an enzyme used to process many drugs). That interaction can raise levels of some medications, including selected antidepressants, antipsychotics, beta blockers such as metoprolol, and certain antiarrhythmics. This does not always mean combinations are unsafe, but it can change monitoring needs or dose choices for the other drug.

It can also interact with digoxin, where careful dose selection and monitoring may be recommended when starting or stopping mirabegron. It is important to share a complete medication list with the prescriber and pharmacist, including over-the-counter cold medicines, stimulants, and herbal products that may affect blood pressure or heart rate. If there is kidney disease, liver disease, or a history of urinary retention, the clinician may adjust therapy plans or choose a different option.

Compare With Alternatives

Overactive bladder care often includes behavioral strategies (timed voiding, fluid timing, pelvic floor therapy) and, when needed, prescription options. Myrbetriq is in a different class than antimuscarinic bladder medications, which may be chosen when a beta-3 agonist is not suitable or when symptom control is incomplete. Antimuscarinics can include oxybutynin, tolterodine, solifenacin, and fesoterodine, among others. Each class has its own side-effect pattern and cautions.

Comparisons usually focus on tolerability, coexisting conditions, and interaction risk rather than a single “best” choice. For example, antimuscarinics may be more likely to cause dry mouth or constipation, while mirabegron may be more relevant to blood pressure monitoring. When reviewing options with a prescriber, it helps to discuss previous trials, side effects that were limiting, and any cardiac history. Related product listings include Oxybutynin Tablets and Vesicare Tablets as examples of other prescription therapies used for similar symptom goals.

Pricing and Access

Myrbetriq cost without insurance can vary based on strength, quantity, and the dispensing pharmacy’s sourcing at the time of fill. Many people look for a Mirabegron tablet option because the active ingredient is mirabegron, and in some settings a generic alternative may be available. A useful background read is Generic Options Explained, which outlines common terminology and what can differ between products.

Access is offered as a cash-pay option for cross-border fills. If you are comparing expected out-of-pocket amounts, Cost Guide Overview summarizes common drivers of variation, such as dose strength and refill cadence. The site may also list Current Promotions when available. To proceed on the site, add the selected strength to your cart and choose prompt, express shipping if it’s offered.

Authoritative Sources

For the most reliable, up-to-date safety details, use official labeling and regulator-backed references. These sources are helpful when confirming interaction cautions, contraindications, and special population considerations such as kidney or liver impairment. They can also clarify what was studied in clinical trials and what monitoring is recommended.

Neutral references to start with include the FDA’s database listing for approved medicines, a patient-friendly monograph from the U.S. National Library of Medicine, and Health Canada’s Drug Product Database for Canadian product listings:

• FDA Drugs@FDA Database
• MedlinePlus Mirabegron Information
• Health Canada Drug Product Database

This content is for informational purposes only and is not a substitute for professional medical advice.